prikaz prve stranice dokumenta Pseudophakic Cystoid Macular Oedema (PCME) Prevention in Patients with Non-Proliferative Diabetic Retinopathy (NPDR)—Randomized Controlled Trial
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Pseudophakic Cystoid Macular Oedema (PCME) Prevention in Patients with Non-Proliferative Diabetic Retinopathy (NPDR)—Randomized Controlled Trial
Medicina, 58 (2022), 11; 1667. https://doi.org/10.3390/medicina58111667
Jukić, Anđela; Kasalica Žužul, Rajka; Pavan, Josip; Lovrić, Mila; Kozmar, Ana; Plavec, Davor; Kuzman, Tomislav; Kalauz, Miro; Jukić, Tomislav

Citirajte ovaj rad

Jukić, A., Kasalica Žužul, R., Pavan, J., Lovrić, M., Kozmar, A., Plavec, D. ... Jukić, T. (2022). Pseudophakic Cystoid Macular Oedema (PCME) Prevention in Patients with Non-Proliferative Diabetic Retinopathy (NPDR)—Randomized Controlled Trial. Medicina, 58. (11). doi: 10.3390/medicina58111667

Jukić, Anđela, et al. "Pseudophakic Cystoid Macular Oedema (PCME) Prevention in Patients with Non-Proliferative Diabetic Retinopathy (NPDR)—Randomized Controlled Trial." Medicina, vol. 58, br. 11, 2022. https://doi.org/10.3390/medicina58111667

Jukić, Anđela, Rajka Kasalica Žužul, Josip Pavan, Mila Lovrić, Ana Kozmar, Davor Plavec, Tomislav Kuzman, Miro Kalauz i Tomislav Jukić. "Pseudophakic Cystoid Macular Oedema (PCME) Prevention in Patients with Non-Proliferative Diabetic Retinopathy (NPDR)—Randomized Controlled Trial." Medicina 58, br. 11 (2022). https://doi.org/10.3390/medicina58111667

Jukić, A., et al. (2022) 'Pseudophakic Cystoid Macular Oedema (PCME) Prevention in Patients with Non-Proliferative Diabetic Retinopathy (NPDR)—Randomized Controlled Trial', Medicina, 58(11). doi: 10.3390/medicina58111667

Jukić A, Kasalica Žužul R, Pavan J, Lovrić M, Kozmar A, Plavec D, i sur.. Pseudophakic Cystoid Macular Oedema (PCME) Prevention in Patients with Non-Proliferative Diabetic Retinopathy (NPDR)—Randomized Controlled Trial. Medicina [Internet]. 17.11.2022. [pristupljeno 24.04.2024.];58(11). doi: 10.3390/medicina58111667

A. Jukić, et al., "Pseudophakic Cystoid Macular Oedema (PCME) Prevention in Patients with Non-Proliferative Diabetic Retinopathy (NPDR)—Randomized Controlled Trial", Medicina, vol. 58, br. 11, Studeni 2022. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:924644. [Citirano: 24.04.2024.]

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Podaci o radu
Naslov (engleski)Pseudophakic Cystoid Macular Oedema (PCME) Prevention in Patients with Non-Proliferative Diabetic Retinopathy (NPDR)—Randomized Controlled Trial
AutorAnđela Jukić
AutorRajka Kasalica Žužul
AutorJosip Pavan
AutorMila Lovrić
AutorAna Kozmar
AutorDavor Plavec
AutorTomislav Kuzman
AutorMiro Kalauz
AutorTomislav Jukić
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA OFTALMOLOGIJU I OPTOMETRIJU)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Oftalmologija
Sažetak (engleski)
Background and Objectives: The purpose of this study was to compare the effect of topical bromfenac and dexamethasone on the intraocular concentration of interleukin 6 (IL-6) and incidence of pseudophakic cystoid macular oedema (PCME) after cataract surgery in patients with non-proliferative diabetic retinopathy (NPDR). Materials and Methods: Ninety eyes of patients with mild-to-moderate NPDR that underwent phacoemulsification cataract surgery were divided into three groups. A detailed description of the clinical study protocol is described later in paper. In short, Group 1 received topical bromfenac (0.9 mg/mL), Group 2 dexamethasone (1 mg/mL), and Group 3 placebo, both preoperatively and postoperatively. Additionally, all patients received combined topical steroid and antibiotic drops (dexamethasone, neomycin and polymyxin B) 3 weeks postoperatively. On the day of the surgery, aqueous humour samples (0.1–0.2 mL) were obtained and IL-6 concentrations were analysed. Central foveal subfield thickness (CFT) measured using spectral-domain optical coherence tomography (SD-OCT) was analysed preoperatively and postoperatively. Results: There was no significant difference in IL-6 concentrations between groups. Postoperative CFT was significantly lower in the dexamethasone group compared to the placebo group. In addition, the correlation between IL-6 and CFT was statistically significant in the dexamethasone group. No patient developed PCME in any of the three groups. No adverse events were reported during the study. Conclusion: Topical bromfenac and dexamethasone have no significant effect on intraocular IL-6 concentration in patients with NPDR. Topical bromfenac is not more effective than topical dexamethasone in reducing postoperative CFT in patients with NPDR.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaMedicina
Brojčani podacivol. 58, br. 11, 1667
e-ISSN1648-9144
DOIhttps://doi.org/10.3390/medicina58111667
URN:NBNurn:nbn:hr:105:924644
Datum objave publikacije2022-11-17
URL dokumentahttps://www.mdpi.com/1648-9144/58/11/1667
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2023-06-19 08:29:54