prikaz prve stranice dokumenta Impact of the SARS-CoV-2 pandemic on the health of individuals with intoxication-type metabolic diseases-Data from the E-IMD consortium
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Impact of the SARS-CoV-2 pandemic on the health of individuals with intoxication-type metabolic diseases-Data from the E-IMD consortium
Journal of Inherited Metabolic Disease, 46 (2022), 2; 220-231. https://doi.org/10.1002/jimd.12572
Mütze, Ulrike; Gleich, Florian; Barić, Ivo; Baumgartner, Mathias; Burlina, Alberto; Chapman, Kimberly A.; Chien, Yin‐Hsiu; Cortès‐Saladelafont, Elisenda; De Laet, Corinne; Dobbelaere, Dries; Eysken, Francois; Gautschi, Matthias; Santer, Rene; Häberle, Johannes; Joaquín, Clara; Karall, Daniela; Lindner, Martin; Lund, Allan M.; Mühlhausen, Chris; Murphy, Elaine; Roland, Dominique; Ruiz Gomez, Angeles; Skouma, Anastasia; Grünert, Sarah C.; Wagenmakers, Margreet; Garbade, Sven F.; Kölker, Stefan; Boy, Nikolas Više autora...

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Mütze, U., Gleich, F., Barić, I., Baumgartner, M., Burlina, A., Chapman, K. A. ... Boy, N. (2022). Impact of the SARS-CoV-2 pandemic on the health of individuals with intoxication-type metabolic diseases-Data from the E-IMD consortium. Journal of Inherited Metabolic Disease, 46. (2), 220-231. doi: 10.1002/jimd.12572

Mütze, Ulrike, et al. "Impact of the SARS-CoV-2 pandemic on the health of individuals with intoxication-type metabolic diseases-Data from the E-IMD consortium." Journal of Inherited Metabolic Disease, vol. 46, br. 2, 2022, str. 220-231. https://doi.org/10.1002/jimd.12572

Mütze, Ulrike, Florian Gleich, Ivo Barić, Mathias Baumgartner, Alberto Burlina, Kimberly A. Chapman, Yin‐Hsiu Chien, et al. "Impact of the SARS-CoV-2 pandemic on the health of individuals with intoxication-type metabolic diseases-Data from the E-IMD consortium." Journal of Inherited Metabolic Disease 46, br. 2 (2022): 220-231. https://doi.org/10.1002/jimd.12572

Mütze, U., et al. (2022) 'Impact of the SARS-CoV-2 pandemic on the health of individuals with intoxication-type metabolic diseases-Data from the E-IMD consortium', Journal of Inherited Metabolic Disease, 46(2), str. 220-231. doi: 10.1002/jimd.12572

Mütze U, Gleich F, Barić I, Baumgartner M, Burlina A, Chapman KA, i sur.. Impact of the SARS-CoV-2 pandemic on the health of individuals with intoxication-type metabolic diseases-Data from the E-IMD consortium. Journal of Inherited Metabolic Disease [Internet]. 14.11.2022. [pristupljeno 27.04.2024.];46(2):220-231. doi: 10.1002/jimd.12572

U. Mütze, et al., "Impact of the SARS-CoV-2 pandemic on the health of individuals with intoxication-type metabolic diseases-Data from the E-IMD consortium", Journal of Inherited Metabolic Disease, vol. 46, br. 2, str. 220-231, Studeni 2022. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:433397. [Citirano: 27.04.2024.]

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Naslov (engleski)Impact of the SARS-CoV-2 pandemic on the health of individuals with intoxication-type metabolic diseases-Data from the E-IMD consortium
AutorUlrike Mütze
AutorFlorian Gleich
AutorIvo Barić
AutorMathias Baumgartner
AutorAlberto Burlina
AutorKimberly A. Chapman
AutorYin‐Hsiu Chien
AutorElisenda Cortès‐Saladelafont
AutorCorinne De Laet
AutorDries Dobbelaere
AutorFrancois Eysken
AutorMatthias Gautschi
AutorRene Santer
AutorJohannes Häberle
AutorClara Joaquín
AutorDaniela Karall
AutorMartin Lindner
AutorAllan M. Lund
AutorChris Mühlhausen
AutorElaine Murphy
AutorDominique Roland
AutorAngeles Ruiz Gomez
AutorAnastasia Skouma
AutorSarah C. Grünert
AutorMargreet Wagenmakers
AutorSven F. Garbade
AutorStefan Kölker
AutorNikolas Boy
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA PEDIJATRIJU)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Pedijatrija
Sažetak (engleski)
The SARS-CoV-2 pandemic challenges healthcare systems worldwide. Within inherited metabolic disorders (IMDs) the vulnerable subgroup of intoxication-type IMDs such as organic acidurias (OA) and urea cycle disorders (UCD) show risk for infection-induced morbidity and mortality. This study (observation period February 2020 to December 2021) evaluates impact on medical health care as well as disease course and outcome of SARS-CoV-2 infections in patients with intoxication-type IMDs managed by participants of the European Registry and Network for intoxication type metabolic diseases Consortium (E-IMD). Survey's respondents managing 792 patients (n = 479 pediatric; n = 313 adult) with intoxication-type IMDs (n = 454 OA; n = 338 UCD) in 14 countries reported on 59 (OA: n = 36; UCD: n = 23), SARS-CoV-2 infections (7.4%). Medical services were increasingly requested (95%), mostly alleviated by remote technologies (86%). Problems with medical supply were scarce (5%). Regular follow-up visits were reduced in 41% (range 10%-50%). Most infected individuals (49/59; 83%) showed mild clinical symptoms, while 10 patients (17%; n = 6 OA including four transplanted MMA patients; n = 4 UCD) were hospitalized (metabolic decompensation in 30%). ICU treatment was not reported. Hospitalization rate did not differ for diagnosis or age group (p = 0.778). Survival rate was 100%. Full recovery was reported for 100% in outpatient care and 90% of hospitalized individuals. SARS-CoV-2 impacts health care of individuals with intoxication-type IMDs worldwide. Most infected individuals, however, showed mild symptoms and did not require hospitalization. SARS-CoV-2-induced metabolic decompensations were usually mild without increased risk for ICU treatment. Overall prognosis of infected individuals is very promising and IMD-specific or COVID-19-related complications have not been observed.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaJournal of Inherited Metabolic Disease
Brojčani podacivol. 46, br. 2, str. 220-231
p-ISSN0141-8955
e-ISSN1573-2665
DOIhttps://doi.org/10.1002/jimd.12572
URN:NBNurn:nbn:hr:105:433397
Datum objave publikacije2022-11-14
URL dokumentahttps://onlinelibrary.wiley.com/doi/10.1002/jimd.12572
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje-Nekomercijalno-Bez prerada 4.0 međunarodna (CC BY-NC-ND 4.0)
Datum i vrijeme pohrane2023-08-21 09:16:13