prikaz prve stranice dokumenta In vitro killing of multidrug/extensively drug-resistant Pseudomonas aeruginosa by fosfomycin alone or in combination with antipseudomonal antibiotics
Rad dostupan nakon 2024-06-01
Znanstveni rad - Izvorni znanstveni rad
In vitro killing of multidrug/extensively drug-resistant Pseudomonas aeruginosa by fosfomycin alone or in combination with antipseudomonal antibiotics
Journal of Chemotherapy, 35 (2022), 3; 219-230. https://doi.org/10.1080/1120009X.2022.2108247
Slade-Vitković, Mia; Bedenić, Branka; Bielen, Luka; Batarilo, Ivanka; Kibel, Sara; Maravić-Vlahoviček, Gordana

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Slade Vitković, M., Bedenić, B., Bielen, L., Batarilo, I., Kibel, S. i Maravić Vlahoviček, G. (2022). In vitro killing of multidrug/extensively drug-resistant Pseudomonas aeruginosa by fosfomycin alone or in combination with antipseudomonal antibiotics. Journal of Chemotherapy, 35. (3), 219-230. doi: 10.1080/1120009X.2022.2108247

Slade Vitković, Mia, et al. "In vitro killing of multidrug/extensively drug-resistant Pseudomonas aeruginosa by fosfomycin alone or in combination with antipseudomonal antibiotics." Journal of Chemotherapy, vol. 35, br. 3, 2022, str. 219-230. https://doi.org/10.1080/1120009X.2022.2108247

Slade Vitković, Mia, Branka Bedenić, Luka Bielen, Ivanka Batarilo, Sara Kibel i Gordana Maravić Vlahoviček. "In vitro killing of multidrug/extensively drug-resistant Pseudomonas aeruginosa by fosfomycin alone or in combination with antipseudomonal antibiotics." Journal of Chemotherapy 35, br. 3 (2022): 219-230. https://doi.org/10.1080/1120009X.2022.2108247

Slade Vitković, M., et al. (2022) 'In vitro killing of multidrug/extensively drug-resistant Pseudomonas aeruginosa by fosfomycin alone or in combination with antipseudomonal antibiotics', Journal of Chemotherapy, 35(3), str. 219-230. doi: 10.1080/1120009X.2022.2108247

Slade Vitković M, Bedenić B, Bielen L, Batarilo I, Kibel S, Maravić Vlahoviček G. In vitro killing of multidrug/extensively drug-resistant Pseudomonas aeruginosa by fosfomycin alone or in combination with antipseudomonal antibiotics. Journal of Chemotherapy [Internet]. 09.08.2022. [pristupljeno 15.04.2024.];35(3):219-230. doi: 10.1080/1120009X.2022.2108247

M. Slade Vitković, B. Bedenić, L. Bielen, I. Batarilo, S. Kibel i G. Maravić Vlahoviček, "In vitro killing of multidrug/extensively drug-resistant Pseudomonas aeruginosa by fosfomycin alone or in combination with antipseudomonal antibiotics", Journal of Chemotherapy, vol. 35, br. 3, str. 219-230, Kolovoz 2022. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:219949. [Citirano: 15.04.2024.]

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Naslov (engleski)In vitro killing of multidrug/extensively drug-resistant Pseudomonas aeruginosa by fosfomycin alone or in combination with antipseudomonal antibiotics
AutorMia Slade-Vitković
AutorBranka Bedenić
AutorLuka Bielen
AutorIvanka Batarilo
AutorSara Kibel
AutorGordana Maravić-Vlahoviček
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA MEDICINSKU MIKROBIOLOGIJU I PARAZITOLOGIJU)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Medicinska mikrobiologija
Sažetak (engleski)
Pseudomonas aeruginosa is a leading cause of nosocomial infections. Given the constant rise in resistance, adequate therapy is increasingly demanding. Fosfomycin recently became an appealing treatment option of bacterial infections due to multidrug-resistant bacteria (MDR). So far, fosfomycin synergy with other antibiotics has been assessed in studies, but only a limited number focused on MDR P. aeruginosa and on the effect of these combinations on the duration of the postantibiotic effect (PAE). We investigated synergy of fosfomycin with an array of antipseudomonal antibiotics using gradient diffusion strip cross method and time-kill method, and their effect on the duration of PAE against 51 variously resistant P. aeruginosa isolates. The highest rate of synergy was observed for combination with ceftazidime (23.4%) and gentamicin (19.1%). The PAE of antibiotic combinations was superior to that of the drugs alone. Our findings indicate that fosfomycin combination therapy may be a valuable treatment alternative.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeZavršna verzija rukopisa prihvaćena za objavljivanje (postprint)
Naslov časopisaJournal of Chemotherapy
Brojčani podacivol. 35, br. 3, str. 219-230
p-ISSN1120-009X
e-ISSN1973-9478
DOIhttps://doi.org/10.1080/1120009X.2022.2108247
URN:NBNurn:nbn:hr:105:219949
Datum objave publikacije2022-08-09
URL dokumentahttps://www.tandfonline.com/doi/full/10.1080/1120009X.2022.2108247
Vrsta resursaTekst
Prava pristupaPristup ograničen embargom
Datum isteka embarga: 2024-06-01
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2023-08-28 08:13:27