prikaz prve stranice dokumenta The Role of Gene Expression in Stress Urinary Incontinence: An Integrative Review of Evidence
  Preuzmi
PDF 928.16 KB
Znanstveni rad - Pregledni rad
The Role of Gene Expression in Stress Urinary Incontinence: An Integrative Review of Evidence
Medicina, 59 (2023), 4; 700. https://doi.org/10.3390/medicina59040700
Miličić, Iva; Mikuš, Mislav; Vrbanić, Adam; Kalafatić, Držislav

Citirajte ovaj rad

Miličić, I., Mikuš, M., Vrbanić, A. i Kalafatić, D. (2023). The Role of Gene Expression in Stress Urinary Incontinence: An Integrative Review of Evidence. Medicina, 59. (4). doi: 10.3390/medicina59040700

Miličić, Iva, et al. "The Role of Gene Expression in Stress Urinary Incontinence: An Integrative Review of Evidence." Medicina, vol. 59, br. 4, 2023. https://doi.org/10.3390/medicina59040700

Miličić, Iva, Mislav Mikuš, Adam Vrbanić i Držislav Kalafatić. "The Role of Gene Expression in Stress Urinary Incontinence: An Integrative Review of Evidence." Medicina 59, br. 4 (2023). https://doi.org/10.3390/medicina59040700

Miličić, I., et al. (2023) 'The Role of Gene Expression in Stress Urinary Incontinence: An Integrative Review of Evidence', Medicina, 59(4). doi: 10.3390/medicina59040700

Miličić I, Mikuš M, Vrbanić A, Kalafatić D. The Role of Gene Expression in Stress Urinary Incontinence: An Integrative Review of Evidence. Medicina [Internet]. 03.04.2023. [pristupljeno 11.04.2024.];59(4). doi: 10.3390/medicina59040700

I. Miličić, M. Mikuš, A. Vrbanić i D. Kalafatić, "The Role of Gene Expression in Stress Urinary Incontinence: An Integrative Review of Evidence", Medicina, vol. 59, br. 4, Travanj 2023. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:928335. [Citirano: 11.04.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:105:928335
Prijavite se u repozitorij kako biste mogli spremiti objekt u svoju listu.
Podaci o radu
Naslov (engleski)The Role of Gene Expression in Stress Urinary Incontinence: An Integrative Review of Evidence
AutorIva Miličić
AutorMislav Mikuš
AutorAdam Vrbanić
AutorDržislav Kalafatić
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA GINEKOLOGIJU I OPSTETRICIJU)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Ginekologija i opstetricija
Sažetak (engleski)
Stress urinary incontinence (SUI) is defined as unintentional urine leakage occurring as a consequence of increased intraabdominal pressure due to absent or weak musculus detrusor contractility. It affects postmenopausal women more often than premenopausal and is associated with quality of life (QoL) deterioration. The complex SUI etiology is generally perceived as multifactorial; however, the overall impact of environmental and genetic influences is deficiently understood. In this research report, we have disclosed the upregulation of 15 genes and the downregulation of 2 genes in the genetic etiology of SUI according to the accessible scientific literature. The analytical methods used for the analysis of gene expression in the studies investigated were immunohistochemistry, immunofluorescence staining, PCR, and Western blot. In order to facilitate the interpretation of the results, we have used GeneMania, a potent software which describes genetic expression, co-expression, co-localization, and protein domain similarity. The importance of this review on the genetic pathophysiology of SUI lies in determining susceptibility for targeted genetic therapy, detecting clinical biomarkers, and other possible therapeutic advances. The prevention of SUI with the timely recognition of genetic factors may be important for avoiding invasive operative urogynecological methods.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Pregledni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaMedicina
Brojčani podacivol. 59, br. 4, 700
e-ISSN1648-9144
DOIhttps://doi.org/10.3390/medicina59040700
URN:NBNurn:nbn:hr:105:928335
Datum objave publikacije2023-04-03
URL dokumentahttps://www.mdpi.com/1648-9144/59/4/700
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2023-11-13 08:54:23