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Healthcare-Associated Bloodstream Infections Due to Multidrug-Resistant Acinetobacter baumannii in COVID-19 Intensive Care Unit: A Single-Center Retrospective Study
Microorganisms, 11 (2023), 3; 774. https://doi.org/10.3390/microorganisms11030774
Dobrović, Karolina; Škrobo, Tea; Selec, Katarina; Jelić, Marko; Čivljak, Rok; Peršec, Jasminka; Sakan, Sanja; Bušić, Nikolina; Mihelčić, Antonija; Hleb, Sonja; Tambić Andrašević, Arjana

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Dobrović, K., Škrobo, T., Selec, K., Jelić, M., Čivljak, R., Peršec, J. ... Tambić Andrašević, A. (2023). Healthcare-Associated Bloodstream Infections Due to Multidrug-Resistant Acinetobacter baumannii in COVID-19 Intensive Care Unit: A Single-Center Retrospective Study. Microorganisms, 11. (3). doi: 10.3390/microorganisms11030774

Dobrović, Karolina, et al. "Healthcare-Associated Bloodstream Infections Due to Multidrug-Resistant Acinetobacter baumannii in COVID-19 Intensive Care Unit: A Single-Center Retrospective Study." Microorganisms, vol. 11, br. 3, 2023. https://doi.org/10.3390/microorganisms11030774

Dobrović, Karolina, Tea Škrobo, Katarina Selec, Marko Jelić, Rok Čivljak, Jasminka Peršec, Sanja Sakan, et al. "Healthcare-Associated Bloodstream Infections Due to Multidrug-Resistant Acinetobacter baumannii in COVID-19 Intensive Care Unit: A Single-Center Retrospective Study." Microorganisms 11, br. 3 (2023). https://doi.org/10.3390/microorganisms11030774

Dobrović, K., et al. (2023) 'Healthcare-Associated Bloodstream Infections Due to Multidrug-Resistant Acinetobacter baumannii in COVID-19 Intensive Care Unit: A Single-Center Retrospective Study', Microorganisms, 11(3). doi: 10.3390/microorganisms11030774

Dobrović K, Škrobo T, Selec K, Jelić M, Čivljak R, Peršec J, i sur.. Healthcare-Associated Bloodstream Infections Due to Multidrug-Resistant Acinetobacter baumannii in COVID-19 Intensive Care Unit: A Single-Center Retrospective Study. Microorganisms [Internet]. 17.03.2023. [pristupljeno 22.11.2024.];11(3). doi: 10.3390/microorganisms11030774

K. Dobrović, et al., "Healthcare-Associated Bloodstream Infections Due to Multidrug-Resistant Acinetobacter baumannii in COVID-19 Intensive Care Unit: A Single-Center Retrospective Study", Microorganisms, vol. 11, br. 3, Ožujak 2023. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:292293. [Citirano: 22.11.2024.]

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Naslov (engleski)Healthcare-Associated Bloodstream Infections Due to Multidrug-Resistant Acinetobacter baumannii in COVID-19 Intensive Care Unit: A Single-Center Retrospective Study
AutorKarolina Dobrović
AutorTea Škrobo
AutorKatarina Selec
AutorMarko Jelić
AutorRok Čivljak
AutorJasminka Peršec
AutorSanja Sakan
AutorNikolina Bušić
AutorAntonija Mihelčić
AutorSonja Hleb
AutorArjana Tambić Andrašević
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA INFEKTOLOGIJU)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Infektologija
Sažetak (engleski)
Healthcare-associated infections are an emerging cause of morbidity and mortality in COVID-19 intensive care units (ICUs) worldwide, especially those caused by multidrug-resistant (MDR) pathogens. The objectives of this study were to assess the incidence of bloodstream infections (BSIs) among critically ill COVID-19 patients and to analyze the characteristics of healthcare-associated BSIs due to MDR Acinetobacter baumannii in an COVID-19 ICU. A single-center retrospective study was conducted at a tertiary hospital during a 5-month period. The detection of carbapenemase genes was performed by PCR and genetic relatedness by pulsed-field gel electrophoresis (PFGE) and multilocus-sequence typing. A total of 193 episodes were registered in 176 COVID-19 ICU patients, with an incidence of 25/1000 patient-days at risk. A. baumannii was the most common etiological agent (40.3%), with a resistance to carbapenems of 100%. The blaOXA-23 gene was detected in ST2 isolates while the blaOXA-24 was ST636-specific. PFGE revealed a homogeneous genetic background of the isolates. The clonal spread of OXA-23-positive A. baumannii is responsible for the high prevalence of MDR A. baumannii BSIs in our COVID-19 ICU. Further surveillance of resistance trends and mechanisms is needed along with changes in behavior to improve the implementation of infection control and the rational use of antibiotics.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaMicroorganisms
Brojčani podacivol. 11, br. 3, 774
e-ISSN2076-2607
DOIhttps://doi.org/10.3390/microorganisms11030774
URN:NBNurn:nbn:hr:105:292293
Datum objave publikacije2023-03-17
URL dokumentahttps://www.mdpi.com/2076-2607/11/3/774
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2024-01-08 09:50:47