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Gender Difference in the Effects of COVID-19 Pandemic on Mechanical Reperfusion and 30-Day Mortality for STEMI: Results of the ISACS-STEMI COVID-19 Registry
Journal of Clinical Medicine, 12 (2023), 3; 896. https://doi.org/10.3390/jcm12030896
De Luca, Giuseppe; Manzo-Silberman, Stephane; Algowhary, Magdy; Uguz, Berat; Oliveira, Dinaldo C.; Ganyukov, Vladimir; Busljetik, Oliver; Cercek, Miha; Okkels, Lisette; Loh, Poay Huan; Calmac, Lucian; Ferrer, Gerard Roura i; Quadros, Alexandre; Milewski, Marek; Scotto di Uccio, Fortunato; von Birgelen, Clemens; Versaci, Francesco; Ten Berg, Jurrien; Casella, Gianni; Wong Sung Lung, Aaron; Kala, Petr; Díez Gil, José Luis; Carrillo, Xavier; Dirksen, Maurits; Becerra, Victor; Lee, Michael Kang-yin; Juzar, Dafsah Arifa; de Moura Joaquim, Rodrigo; Paladino, Roberto; Miličić, Davor; Davlouros, Periklis; Bakraceski, Nikola; Zilio, Filippo; Donazzan, Luca; Kraaijeveld, Adriaan; Galasso, Gennaro; Arpad, Lux; Marinucci, Lucia; Guiducci, Vincenzo; Menichelli, Maurizio; Scoccia, Alessandra; Yamac, Aylin Hatice; Ugur Mert, Kadir; Flores Rios, Xacobe; Kovarnik, Tomas; Kidawa, Michal; Moreu, Josè; Flavien, Vincent; Fabris, Enrico; Martínez-Luengas, Iñigo Lozano; Boccalatte, Marco; Ojeda, Francisco Bosa; Arellano-Serrano, Carlos; Caiazzo, Gianluca; Cirrincione, Giuseppe; Kao, Hsien-Li; Forés, Juan Sanchis; Vignali, Luigi; Pereira, Helder; Ordoñez, Santiago; Arat Özkan, Alev; Scheller, Bruno; Lehtola, Heidi; Teles, Rui; Mantis, Christos; Antti, Ylitalo; Brum Silveira, João António; Zoni, Cesar Rodrigo; Bessonov, Ivan; Uccello, Giuseppe; Kochiadakis, George; Alexopulos, Dimitrios; Uribe, Carlos E.; Kanakakis, John; Faurie, Benjamin; Gabrielli, Gabriele; Barrios, Alejandro Gutierrez; Bachini, Juan Pablo; Rocha, Alex; Tam, Frankie C. C.; Rodriguez, Alfredo; Lukito, Antonia Anna; Saint-Joy, Veauthyelau; Pessah, Gustavo; Tuccillo, Andrea; Ielasi, Alfonso; Cortese, Giuliana; Parodi, Guido; Bouraghda, Mohamed Abed; Moura, Marcia; Kedhi, Elvin; Lamelas, Pablo; Suryapranata, Harry; Nardin, Matteo; Verdoia, Monica Više autora...

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De Luca, G., Manzo Silberman, S., Algowhary, M., Uguz, B., Oliveira, D. C., Ganyukov, V. ... Verdoia, M. (2023). Gender Difference in the Effects of COVID-19 Pandemic on Mechanical Reperfusion and 30-Day Mortality for STEMI: Results of the ISACS-STEMI COVID-19 Registry. Journal of Clinical Medicine, 12. (3). doi: 10.3390/jcm12030896

De Luca, Giuseppe, et al. "Gender Difference in the Effects of COVID-19 Pandemic on Mechanical Reperfusion and 30-Day Mortality for STEMI: Results of the ISACS-STEMI COVID-19 Registry." Journal of Clinical Medicine, vol. 12, br. 3, 2023. https://doi.org/10.3390/jcm12030896

De Luca, Giuseppe, Stephane Manzo Silberman, Magdy Algowhary, Berat Uguz, Dinaldo C. Oliveira, Vladimir Ganyukov, Oliver Busljetik, et al. "Gender Difference in the Effects of COVID-19 Pandemic on Mechanical Reperfusion and 30-Day Mortality for STEMI: Results of the ISACS-STEMI COVID-19 Registry." Journal of Clinical Medicine 12, br. 3 (2023). https://doi.org/10.3390/jcm12030896

De Luca, G., et al. (2023) 'Gender Difference in the Effects of COVID-19 Pandemic on Mechanical Reperfusion and 30-Day Mortality for STEMI: Results of the ISACS-STEMI COVID-19 Registry', Journal of Clinical Medicine, 12(3). doi: 10.3390/jcm12030896

De Luca G, Manzo Silberman S, Algowhary M, Uguz B, Oliveira DC, Ganyukov V, i sur.. Gender Difference in the Effects of COVID-19 Pandemic on Mechanical Reperfusion and 30-Day Mortality for STEMI: Results of the ISACS-STEMI COVID-19 Registry. Journal of Clinical Medicine [Internet]. 23.01.2023. [pristupljeno 11.04.2024.];12(3). doi: 10.3390/jcm12030896

G. De Luca, et al., "Gender Difference in the Effects of COVID-19 Pandemic on Mechanical Reperfusion and 30-Day Mortality for STEMI: Results of the ISACS-STEMI COVID-19 Registry", Journal of Clinical Medicine, vol. 12, br. 3, Siječanj 2023. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:321340. [Citirano: 11.04.2024.]

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Naslov (engleski)Gender Difference in the Effects of COVID-19 Pandemic on Mechanical Reperfusion and 30-Day Mortality for STEMI: Results of the ISACS-STEMI COVID-19 Registry
AutorGiuseppe De Luca
AutorStephane Manzo-Silberman
AutorMagdy Algowhary
AutorBerat Uguz
AutorDinaldo C. Oliveira
AutorVladimir Ganyukov
AutorOliver Busljetik
AutorMiha Cercek
AutorLisette Okkels
AutorPoay Huan Loh
AutorLucian Calmac
AutorGerard Roura i Ferrer
AutorAlexandre Quadros
AutorMarek Milewski
AutorFortunato Scotto di Uccio
AutorClemens von Birgelen
AutorFrancesco Versaci
AutorJurrien Ten Berg
AutorGianni Casella
AutorAaron Wong Sung Lung
AutorPetr Kala
AutorJosé Luis Díez Gil
AutorXavier Carrillo
AutorMaurits Dirksen
AutorVictor Becerra
AutorMichael Kang-yin Lee
AutorDafsah Arifa Juzar
AutorRodrigo de Moura Joaquim
AutorRoberto Paladino
AutorDavor Miličić
AutorPeriklis Davlouros
AutorNikola Bakraceski
AutorFilippo Zilio
AutorLuca Donazzan
AutorAdriaan Kraaijeveld
AutorGennaro Galasso
AutorLux Arpad
AutorLucia Marinucci
AutorVincenzo Guiducci
AutorMaurizio Menichelli
AutorAlessandra Scoccia
AutorAylin Hatice Yamac
AutorKadir Ugur Mert
AutorXacobe Flores Rios
AutorTomas Kovarnik
AutorMichal Kidawa
AutorJosè Moreu
AutorVincent Flavien
AutorEnrico Fabris
AutorIñigo Lozano Martínez-Luengas
AutorMarco Boccalatte
AutorFrancisco Bosa Ojeda
AutorCarlos Arellano-Serrano
AutorGianluca Caiazzo
AutorGiuseppe Cirrincione
AutorHsien-Li Kao
AutorJuan Sanchis Forés
AutorLuigi Vignali
AutorHelder Pereira
AutorSantiago Ordoñez
AutorAlev Arat Özkan
AutorBruno Scheller
AutorHeidi Lehtola
AutorRui Teles
AutorChristos Mantis
AutorYlitalo Antti
AutorJoão António Brum Silveira
AutorCesar Rodrigo Zoni
AutorIvan Bessonov
AutorGiuseppe Uccello
AutorGeorge Kochiadakis
AutorDimitrios Alexopulos
AutorCarlos E. Uribe
AutorJohn Kanakakis
AutorBenjamin Faurie
AutorGabriele Gabrielli
AutorAlejandro Gutierrez Barrios
AutorJuan Pablo Bachini
AutorAlex Rocha
AutorFrankie C. C. Tam
AutorAlfredo Rodriguez
AutorAntonia Anna Lukito
AutorVeauthyelau Saint-Joy
AutorGustavo Pessah
AutorAndrea Tuccillo
AutorAlfonso Ielasi
AutorGiuliana Cortese
AutorGuido Parodi
AutorMohamed Abed Bouraghda
AutorMarcia Moura
AutorElvin Kedhi
AutorPablo Lamelas
AutorHarry Suryapranata
AutorMatteo Nardin
AutorMonica Verdoia
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA INTERNU MEDICINU)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Interna medicina
Sažetak (engleski)
Background: Several reports have demonstrated the impact of the COVID-19 pandemic on the management and outcome of patients with ST-segment elevation myocardial infarction (STEMI). The aim of the current analysis is to investigate the potential gender difference in the effects of the COVID-19 pandemic on mechanical reperfusion and 30-day mortality for STEMI patients within the ISACS-STEMI COVID-19 Registry. Methods: This retrospective multicenter registry was performed in high-volume primary percutaneous coronary intervention (PPCI) centers on four continents and included STEMI patients undergoing PPCIs in March-June 2019 and 2020. Patients were divided according to gender. The main outcomes were the incidence and timing of the PPCI, (ischemia time ≥ 12 h and door-to-balloon ≥ 30 min) and in-hospital or 30-day mortality. Results: We included 16683 STEMI patients undergoing PPCIs in 109 centers. In 2020 during the pandemic, there was a significant reduction in PPCIs compared to 2019 (IRR 0.843 (95% CI: 0.825-0.861, p < 0.0001). We did not find a significant gender difference in the effects of the COVID-19 pandemic on the numbers of STEMI patients, which were similarly reduced from 2019 to 2020 in both groups, or in the mortality rates. Compared to prepandemia, 30-day mortality was significantly higher during the pandemic period among female (12.1% vs. 8.7%; adjusted HR [95% CI] = 1.66 [1.31-2.11], p < 0.001) but not male patients (5.8% vs. 6.7%; adjusted HR [95% CI] = 1.14 [0.96-1.34], p = 0.12). Conclusions: The COVID-19 pandemic had a significant impact on the treatment of patients with STEMI, with a 16% reduction in PPCI procedures similarly observed in both genders. Furthermore, we observed significantly increased in-hospital and 30-day mortality rates during the pandemic only among females. Trial registration number: NCT 04412655.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaJournal of Clinical Medicine
Brojčani podacivol. 12, br. 3, 896
e-ISSN2077-0383
DOIhttps://doi.org/10.3390/jcm12030896
URN:NBNurn:nbn:hr:105:321340
Datum objave publikacije2023-01-23
URL dokumentahttps://www.mdpi.com/2077-0383/12/3/896
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje-Nekomercijalno-Bez prerada 3.0 (CC BY-NC-ND 3.0)
Datum i vrijeme pohrane2024-01-16 08:57:54