prikaz prve stranice dokumenta A Novel Three-Dimensional Approach Towards Evaluating Endomyocardial Biopsies for Follow-Up After Heart Transplantation: X-Ray Phase Contrast Imaging and Its Agreement With Classical Histopathology
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A Novel Three-Dimensional Approach Towards Evaluating Endomyocardial Biopsies for Follow-Up After Heart Transplantation: X-Ray Phase Contrast Imaging and Its Agreement With Classical Histopathology
Transplant International, 36 (2023); 11046. https://doi.org/10.3389/ti.2023.11046
Planinc, Ivo; Ilić, Ivana; Dejea, Hector; Garcia-Canadilla, Patricia; Gašparović, Hrvoje; Jurin, Hrvoje; Miličić, Davor; Skorić, Boško; Stampanoni, Marco; Bijnens, Bart; Bonnin, Anne; Čikes, Maja

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Planinc, I., Ilić, I., Dejea, H., Garcia Canadilla, P., Gašparović, H., Jurin, H. ... Čikes, M. (2023). A Novel Three-Dimensional Approach Towards Evaluating Endomyocardial Biopsies for Follow-Up After Heart Transplantation: X-Ray Phase Contrast Imaging and Its Agreement With Classical Histopathology. Transplant International, 36.. doi: 10.3389/ti.2023.11046

Planinc, Ivo, et al. "A Novel Three-Dimensional Approach Towards Evaluating Endomyocardial Biopsies for Follow-Up After Heart Transplantation: X-Ray Phase Contrast Imaging and Its Agreement With Classical Histopathology." Transplant International, vol. 36, 2023. https://doi.org/10.3389/ti.2023.11046

Planinc, Ivo, Ivana Ilić, Hector Dejea, Patricia Garcia Canadilla, Hrvoje Gašparović, Hrvoje Jurin, Davor Miličić, et al. "A Novel Three-Dimensional Approach Towards Evaluating Endomyocardial Biopsies for Follow-Up After Heart Transplantation: X-Ray Phase Contrast Imaging and Its Agreement With Classical Histopathology." Transplant International 36 (2023). https://doi.org/10.3389/ti.2023.11046

Planinc, I., et al. (2023) 'A Novel Three-Dimensional Approach Towards Evaluating Endomyocardial Biopsies for Follow-Up After Heart Transplantation: X-Ray Phase Contrast Imaging and Its Agreement With Classical Histopathology', Transplant International, 36. doi: 10.3389/ti.2023.11046

Planinc I, Ilić I, Dejea H, Garcia Canadilla P, Gašparović H, Jurin H, i sur.. A Novel Three-Dimensional Approach Towards Evaluating Endomyocardial Biopsies for Follow-Up After Heart Transplantation: X-Ray Phase Contrast Imaging and Its Agreement With Classical Histopathology. Transplant International [Internet]. 24.01.2023. [pristupljeno 19.04.2024.];36. doi: 10.3389/ti.2023.11046

I. Planinc, et al., "A Novel Three-Dimensional Approach Towards Evaluating Endomyocardial Biopsies for Follow-Up After Heart Transplantation: X-Ray Phase Contrast Imaging and Its Agreement With Classical Histopathology", Transplant International, vol. 36, Siječanj 2023. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:874985. [Citirano: 19.04.2024.]

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Naslov (engleski)A Novel Three-Dimensional Approach Towards Evaluating Endomyocardial Biopsies for Follow-Up After Heart Transplantation: X-Ray Phase Contrast Imaging and Its Agreement With Classical Histopathology
AutorIvo Planinc
AutorIvana Ilić
AutorHector Dejea
AutorPatricia Garcia-Canadilla
AutorHrvoje Gašparović
AutorHrvoje Jurin
AutorDavor Miličić
AutorBoško Skorić
AutorMarco Stampanoni
AutorBart Bijnens
AutorAnne Bonnin
AutorMaja Čikes
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA INTERNU MEDICINU)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Interna medicina
Sažetak (engleski)
Endomyocardial biopsies are the gold standard for surveillance of graft rejection following heart transplantation, and are assessed by classical histopathology using a limited number of previously stained slices from several biopsies. Synchrotron propagation-based X-ray phase contrast imaging is a non-destructive method to image biological samples without tissue preparation, enabling virtual 2D and 3D histopathology. We aimed to show the feasibility of this method to assess acute cellular rejection and its agreement to classical histopathology. Right ventricular biopsies were sampled from 23 heart transplantation recipients (20 males, mean age 54±14 years) as part of standard follow-up. The clinical diagnosis of potential rejection was made using classical histopathology. One additional study sample was harvested and imaged by X-ray phase contrast imaging, producing 3D datasets with 0.65 μm pixel size, and up to 4,320 images per sample. An experienced pathologist graded both histopathological and X-ray phase contrast images in a blinded fashion. The agreement between methods was assessed by weighted kappa, showing substantial agreement (kappa up to 0.80, p < 0.01) between X-ray phase contrast imaging and classical histopathology. X-ray phase contrast imaging does not require tissue processing, allows thorough analysis of a full myocardial sample and allows identification of acute cellular rejection.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaTransplant International
Brojčani podacivol. 36, 11046
e-ISSN1432-2277
DOIhttps://doi.org/10.3389/ti.2023.11046
URN:NBNurn:nbn:hr:105:874985
Datum objave publikacije2023-01-24
ProjektŠifra: IP-2020-02-5572
Naziv (hrvatski): Nova paradigma utvrđivanja odbacivanja presatka srca: dijagnostika fazno-kontrastnim oslikavanjem X-zrakama proizvedenim sinkrotronom
Naziv (engleski): New Paradigm in Graft Rejection Detection in Heart Transplantation Recipients: Diagnostic Utility of Synchrotron X-ray Phase Contrast Imaging
Kratica: GRAFT-XPCI
Voditelj: Maja Čikeš
Pravna nadležnost: Hrvatska
Financijer: HRZZ
Linija financiranja: Nema
URL dokumentahttps://www.frontierspartnerships.org/articles/10.3389/ti.2023.11046/full
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2024-01-16 09:12:29