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Multidrug-Resistant Bacteria in a COVID-19 Hospital in Zagreb
Pathogens, 12 (2023), 1; 117. https://doi.org/10.3390/pathogens12010117
Bedenić, Branka; Bratić, Vesna; Mihaljević, Slobodan; Lukić, Anita; Vidović, Karlo; Reiner, Krešimir; Schöenthaler, Silvia; Barišić, Ivan; Zarfel, Gernot; Grisold, Andrea

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Bedenić, B., Bratić, V., Mihaljević, S., Lukić, A., Vidović, K., Reiner, K. ... Grisold, A. (2023). Multidrug-Resistant Bacteria in a COVID-19 Hospital in Zagreb. Pathogens, 12. (1). doi: 10.3390/pathogens12010117

Bedenić, Branka, et al. "Multidrug-Resistant Bacteria in a COVID-19 Hospital in Zagreb." Pathogens, vol. 12, br. 1, 2023. https://doi.org/10.3390/pathogens12010117

Bedenić, Branka, Vesna Bratić, Slobodan Mihaljević, Anita Lukić, Karlo Vidović, Krešimir Reiner, Silvia Schöenthaler, Ivan Barišić, Gernot Zarfel i Andrea Grisold. "Multidrug-Resistant Bacteria in a COVID-19 Hospital in Zagreb." Pathogens 12, br. 1 (2023). https://doi.org/10.3390/pathogens12010117

Bedenić, B., et al. (2023) 'Multidrug-Resistant Bacteria in a COVID-19 Hospital in Zagreb', Pathogens, 12(1). doi: 10.3390/pathogens12010117

Bedenić B, Bratić V, Mihaljević S, Lukić A, Vidović K, Reiner K, i sur.. Multidrug-Resistant Bacteria in a COVID-19 Hospital in Zagreb. Pathogens [Internet]. 10.01.2023. [pristupljeno 19.12.2024.];12(1). doi: 10.3390/pathogens12010117

B. Bedenić, et al., "Multidrug-Resistant Bacteria in a COVID-19 Hospital in Zagreb", Pathogens, vol. 12, br. 1, Siječanj 2023. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:817919. [Citirano: 19.12.2024.]

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Podaci o radu
Naslov (engleski)Multidrug-Resistant Bacteria in a COVID-19 Hospital in Zagreb
AutorBranka Bedenić
AutorVesna Bratić
AutorSlobodan Mihaljević
AutorAnita Lukić
AutorKarlo Vidović
AutorKrešimir Reiner
AutorSilvia Schöenthaler
AutorIvan Barišić
AutorGernot Zarfel
AutorAndrea Grisold
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA MEDICINSKU MIKROBIOLOGIJU I PARAZITOLOGIJU)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Anesteziologija i reanimatologija
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Medicinska mikrobiologija
Sažetak (engleski)
During November to December 2020, a high rate of COVID-19-associated pneumonia with bacterial superinfections due to multidrug-resistant (MDR) pathogens was recorded in a COVID-19 hospital in Zagreb. This study analyzed the causative agents of bacterial superinfections among patients with serious forms of COVID-19. In total, 118 patients were hospitalized in the intensive care unit (ICU) of the COVID-19 hospital. Forty-six out of 118 patients (39%) developed serious bacterial infection (VAP or BSI or both) during their stay in ICU. The total mortality rate was 83/118 (70%). The mortality rate due to bacterial infection or a combination of ARDS with bacterial superinfection was 33% (40/118). Six patients had MDR organisms and 34 had XDR (extensively drug-resistant). The dominant species was Acinetobacter baumannii with all isolates (34) being carbapenem-resistant (CRAB) and positive for carbapenem-hydrolyzing oxacillinases (CHDL). One Escherichia coli causing pneumonia harboured the blaCTX-M-15 gene. It appears that the dominant resistance determinants of causative agents depend on the local epidemiology in the particular COVID center. Acinetobacter baumannii seems to easily spread in overcrowded ICUs. Croatia belongs to the 15 countries in the world with the highest mortality rate among COVID-19 patients, which could be in part attributable to the high prevalence of bacterial infections in local ICUs.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaPathogens
Brojčani podacivol. 12, br. 1, 117
e-ISSN2076-0817
DOIhttps://doi.org/10.3390/pathogens12010117
URN:NBNurn:nbn:hr:105:817919
Datum objave publikacije2023-01-10
URL dokumentahttps://www.mdpi.com/2076-0817/12/1/117
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2024-01-23 09:26:48