prikaz prve stranice dokumenta Association between Serum Free Fatty Acids and Clinical and Laboratory Parameters in Acute Heart Failure Patients
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Association between Serum Free Fatty Acids and Clinical and Laboratory Parameters in Acute Heart Failure Patients
Biomedicines, 11 (2023), 12; 3197. https://doi.org/10.3390/biomedicines11123197
Klobučar, Iva; Hinteregger, Helga; Lechleitner, Margarete; Trbušić, Matias; Pregartner, Gudrun; Berghold, Andrea; Sattler, Wolfgang; Frank, Saša; Degoricija, Vesna

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Klobučar, I., Hinteregger, H., Lechleitner, M., Trbušić, M., Pregartner, G., Berghold, A. ... Degoricija, V. (2023). Association between Serum Free Fatty Acids and Clinical and Laboratory Parameters in Acute Heart Failure Patients. Biomedicines, 11. (12). doi: 10.3390/biomedicines11123197

Klobučar, Iva, et al. "Association between Serum Free Fatty Acids and Clinical and Laboratory Parameters in Acute Heart Failure Patients." Biomedicines, vol. 11, br. 12, 2023. https://doi.org/10.3390/biomedicines11123197

Klobučar, Iva, Helga Hinteregger, Margarete Lechleitner, Matias Trbušić, Gudrun Pregartner, Andrea Berghold, Wolfgang Sattler, Saša Frank i Vesna Degoricija. "Association between Serum Free Fatty Acids and Clinical and Laboratory Parameters in Acute Heart Failure Patients." Biomedicines 11, br. 12 (2023). https://doi.org/10.3390/biomedicines11123197

Klobučar, I., et al. (2023) 'Association between Serum Free Fatty Acids and Clinical and Laboratory Parameters in Acute Heart Failure Patients', Biomedicines, 11(12). doi: 10.3390/biomedicines11123197

Klobučar I, Hinteregger H, Lechleitner M, Trbušić M, Pregartner G, Berghold A, i sur.. Association between Serum Free Fatty Acids and Clinical and Laboratory Parameters in Acute Heart Failure Patients. Biomedicines [Internet]. 01.12.2023. [pristupljeno 09.11.2024.];11(12). doi: 10.3390/biomedicines11123197

I. Klobučar, et al., "Association between Serum Free Fatty Acids and Clinical and Laboratory Parameters in Acute Heart Failure Patients", Biomedicines, vol. 11, br. 12, Prosinac 2023. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:499956. [Citirano: 09.11.2024.]

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Podaci o radu
Naslov (engleski)Association between Serum Free Fatty Acids and Clinical and Laboratory Parameters in Acute Heart Failure Patients
AutorIva Klobučar
AutorHelga Hinteregger
AutorMargarete Lechleitner
AutorMatias Trbušić
AutorGudrun Pregartner
AutorAndrea Berghold
AutorWolfgang Sattler
AutorSaša Frank
AutorVesna Degoricija
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA INTERNU MEDICINU)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Sažetak (engleski)
Very little is known about the association between individual serum free fatty acids (FFAs) and clinical and laboratory parameters (indicators of heart failure severity) in acute heart failure (AHF) patients. Here, the baseline serum levels of FFAs, 16:0 (palmitic acid), 16:1 (palmitoleic acid), 18:0 (stearic acid), 18:1 (oleic acid), 18:2 (linoleic acid), 18:3 (alpha-linolenic acid or gamma-linolenic acid), 20:4 (arachidonic acid), 20:5 (eicosapentaenoic acid), and 22:6 (docosahexaenoic acid), were determined in 304 AHF patients (94.7% belonged to New York Heart Association functional class IV) using gas chromatography. Spearman correlation coefficients were used to examine the associations between the individual and total (the sum of all FFAs) FFAs and clinical and laboratory parameters. After applying a Bonferroni correction to correct for multiple testing, the total FFAs, as well as the individual FFAs (except FFAs 18:0, 20:5, and 22:6), were found to be significantly positively correlated with serum albumin. Only a few additional associations were found: FFA 16:0 was significantly negatively correlated with systolic pulmonary artery pressure, FFA 18:3 was significantly negatively correlated with C-reactive protein and body mass index, and FFA 20:4 was significantly negatively correlated with blood urea nitrogen. Based on our results, we conclude that in patients with severe AHF, individual and total serum FFAs are slightly associated with established laboratory and clinical parameters, which are indicators of heart failure severity.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaBiomedicines
Brojčani podacivol. 11, br. 12, 3197
e-ISSN2227-9059
DOIhttps://doi.org/10.3390/biomedicines11123197
URN:NBNurn:nbn:hr:105:499956
Datum objave publikacije2023-12-01
URL dokumentahttps://www.mdpi.com/2227-9059/11/12/3197
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2024-03-04 09:53:03