prikaz prve stranice dokumenta Prognostic significance of glomerular and tubulointerstitial morphometry in idiopathic membranous nephropathy
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Prognostic significance of glomerular and tubulointerstitial morphometry in idiopathic membranous nephropathy
Pathology, Research and Practice, 208 (2012), 11; 662-667. https://doi.org/10.1016/j.prp.2012.08.004
Horvatić, Ivica; Galešić Ljubanović, Danica; Bulimbašić, Stela; Knotek, Mladen; Prkačin, Ingrid; Tišljar, Miroslav; Galešić, Krešimir

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Horvatić, I., Galešić Ljubanović, D., Bulimbašić, S., Knotek, M., Prkačin, I., Tišljar, M. i Galešić, K. (2012). Prognostic significance of glomerular and tubulointerstitial morphometry in idiopathic membranous nephropathy. Pathology, Research and Practice, 208. (11), 662-667. doi: 10.1016/j.prp.2012.08.004

Horvatić, Ivica, et al. "Prognostic significance of glomerular and tubulointerstitial morphometry in idiopathic membranous nephropathy." Pathology, Research and Practice, vol. 208, br. 11, 2012, str. 662-667. https://doi.org/10.1016/j.prp.2012.08.004

Horvatić, Ivica, Danica Galešić Ljubanović, Stela Bulimbašić, Mladen Knotek, Ingrid Prkačin, Miroslav Tišljar i Krešimir Galešić. "Prognostic significance of glomerular and tubulointerstitial morphometry in idiopathic membranous nephropathy." Pathology, Research and Practice 208, br. 11 (2012): 662-667. https://doi.org/10.1016/j.prp.2012.08.004

Horvatić, I., et al. (2012) 'Prognostic significance of glomerular and tubulointerstitial morphometry in idiopathic membranous nephropathy', Pathology, Research and Practice, 208(11), str. 662-667. doi: 10.1016/j.prp.2012.08.004

Horvatić I, Galešić Ljubanović D, Bulimbašić S, Knotek M, Prkačin I, Tišljar M, i sur.. Prognostic significance of glomerular and tubulointerstitial morphometry in idiopathic membranous nephropathy. Pathology, Research and Practice [Internet]. 15.11.2012. [pristupljeno 11.04.2024.];208(11):662-667. doi: 10.1016/j.prp.2012.08.004

I. Horvatić, et al., "Prognostic significance of glomerular and tubulointerstitial morphometry in idiopathic membranous nephropathy", Pathology, Research and Practice, vol. 208, br. 11, str. 662-667, Studeni 2012. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:547632. [Citirano: 11.04.2024.]

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Podaci o radu
Naslov (engleski)Prognostic significance of glomerular and tubulointerstitial morphometry in idiopathic membranous nephropathy
AutorIvica Horvatić
AutorDanica Galešić Ljubanović
AutorStela Bulimbašić
AutorMladen Knotek
AutorIngrid Prkačin
AutorMiroslav Tišljar
AutorKrešimir Galešić
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Sažetak (engleski)
The purpose of our study was to investigate the prognostic value of clinical and pathological, in particular glomerular and tubulointerstitial morphometric variables in idiopathic membranous nephropathy (IMN). We prospectively followed 60 Caucasian patients diagnosed with idiopathic membranous nephropathy for at least 2 years or until primary outcome (≥50% permanent decrease in estimated glomerular filtration rate or death). Glomerular and tubulointerstitial morphometric variables at the time of renal biopsy were analyzed with respect to this outcome. Univariate analysis revealed that significant negative prognostic factors for this outcome were higher cholesterol and smaller albumin concentrations, higher creatinine and maximal 24-h proteinuria, higher grade of nephroangiosclerosis, higher glomerular basement membrane thickness and glomerulopathy index, higher interstitial fibrosis and tubular atrophy percentage and higher injury score. In multivariate analysis, only the maximal 24-h proteinuria and interstitial fibrosis and tubular atrophy percentage were independent predictors of this outcome. The results suggest that morphometric analysis, mainly quantitative measurement of interstitial fibrosis and tubular atrophy percentage, injury score, glomerular basement membrane thickness and glomerulopathy index could be used as an additional method for risk stratification of patients with idiopathic membranous nephropathy.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeZavršna verzija rukopisa prihvaćena za objavljivanje (postprint)
Naslov časopisaPathology, Research and Practice
Brojčani podacivol. 208, br. 11, str. 662-667
p-ISSN0344-0338
DOIhttps://doi.org/10.1016/j.prp.2012.08.004
URN:NBNurn:nbn:hr:105:547632
Datum objave publikacije2012-11-15
URL dokumentahttps://doi.org/10.1016/j.prp.2012.08.004
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2024-03-27 19:41:30