prikaz prve stranice dokumenta "Compensated hyperosmolarity" of cerebrospinal fluid and the development of hydrocephalus
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"Compensated hyperosmolarity" of cerebrospinal fluid and the development of hydrocephalus
Neuroscience, 248 (2013); 278-289. https://doi.org/10.1016/j.neuroscience.2013.06.022
Klarica, Marijan; Miše, Branko; Vladić, Anton; Radoš, Milan; Orešković, Darko

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Klarica, M., Miše, B., Vladić, A., Radoš, M. i Orešković, D. (2013). "Compensated hyperosmolarity" of cerebrospinal fluid and the development of hydrocephalus. Neuroscience, 248., 278-289. doi: 10.1016/j.neuroscience.2013.06.022

Klarica, Marijan, et al. ""Compensated hyperosmolarity" of cerebrospinal fluid and the development of hydrocephalus." Neuroscience, vol. 248, 2013, str. 278-289. https://doi.org/10.1016/j.neuroscience.2013.06.022

Klarica, Marijan, Branko Miše, Anton Vladić, Milan Radoš i Darko Orešković. ""Compensated hyperosmolarity" of cerebrospinal fluid and the development of hydrocephalus." Neuroscience 248 (2013): 278-289. https://doi.org/10.1016/j.neuroscience.2013.06.022

Klarica, M., et al. (2013) '"Compensated hyperosmolarity" of cerebrospinal fluid and the development of hydrocephalus', Neuroscience, 248, str. 278-289. doi: 10.1016/j.neuroscience.2013.06.022

Klarica M, Miše B, Vladić A, Radoš M, Orešković D. "Compensated hyperosmolarity" of cerebrospinal fluid and the development of hydrocephalus. Neuroscience [Internet]. 24.06.2013. [pristupljeno 10.04.2024.];248:278-289. doi: 10.1016/j.neuroscience.2013.06.022

M. Klarica, B. Miše, A. Vladić, M. Radoš i D. Orešković, ""Compensated hyperosmolarity" of cerebrospinal fluid and the development of hydrocephalus", Neuroscience, vol. 248, str. 278-289, Lipanj 2013. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:329752. [Citirano: 10.04.2024.]

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Podaci o radu
Naslov (engleski)"Compensated hyperosmolarity" of cerebrospinal fluid and the development of hydrocephalus
AutorMarijan Klarica
AutorBranko Miše
AutorAnton Vladić
AutorMilan Radoš
AutorDarko Orešković
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Temeljne medicinske znanosti
Sažetak (engleski)
Acute osmolar loading of cerebrospinal fluid within one lateral ventricle of dogs was examined as a cause of water extraction from the bloodstream and an increase in intracranial pressure. We have shown that a certain amount of 3H2O from the bloodstream enters osmotically loaded cerebrospinal fluid significantly faster, hence causing a significant increase in intracranial pressure. The noted phenomenon in which intracranial pressure still significantly increases, but in which the hyperosmolarity of the cerebrospinal fluid is no longer present, was named "compensated hyperosmolarity". In the case of the sub-chronic application of hyperosmolar solutions into cat ventricles, we observed an increase in cerebrospinal fluid volume and a more pronounced development of hydrocephalus in the area of application, but without significant increase in intracranial pressure and without blockage of cerebrospinal fluid pathways. These results support the newly proposed hypothesis of cerebrospinal fluid hydrodynamics and the ability to develop new strategies for the treatment of cerebrospinal fluid-related diseases. ----- KEYWORDS: CM, CP, CSF, HRP, ICP, ISF, LLV, RLV, SAS, SD, cerebrospinal fluid, cerebrospinal fluid hydrodynamics, cerebrospinal fluid hyperosmolarity, choroid plexus, cisterna magna, horseradish peroxidase, hydrocephalus, interstitial fluid, intracranial pressure, left lateral ventricle, right lateral ventricle, standard deviation, subarachnoid space
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeZavršna verzija rukopisa prihvaćena za objavljivanje (postprint)
Naslov časopisaNeuroscience
Brojčani podacivol. 248, str. 278-289
p-ISSN0306-4522
DOIhttps://doi.org/10.1016/j.neuroscience.2013.06.022
URN:NBNurn:nbn:hr:105:329752
Datum objave publikacije2013-06-24
URL dokumentahttps://doi.org/10.1016/j.neuroscience.2013.06.022
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2024-03-27 19:51:11