Lower limb salvage surgery: modular endoprosthesis in bone tumour treatment

Znanstveni rad - Izvorni znanstveni rad

• Autor: Dubravko Orlić
• Autor: Miroslav Smerdelj
• Autor: Robert Kolundžić
• Autor: Marko Bergovec
• Autorova ustanova: Sveučilište u Zagrebu; Medicinski fakultet
• Znanstveno / umjetničko područje, polje i grana: BIOMEDICINA I ZDRAVSTVO; Kliničke medicinske znanosti

Sažetak (engleski)

We retrospectively analysed 90 patients who underwent "en bloc" resection and modular endoprosthesis reconstruction in the lower limbs between 1987-2003. After proximal femur resection, reconstruction was performed with a modular endoprosthesis by Howmedica (KFTR, designed by Kotz) and modular revision endoprosthesis by W. Link or Lima-Lto (Revision system, designed by Wagner). The knee joint was reconstructed with a modular endoprosthesis (Howmedica, KFTR designed by Kotz) after distal femur or proximal tibia resection. Malignant bone tumours were present in 58 patients (64.5%), benign tumours in 16 (17.8%), metastases in 8 (8.9%), tumour-like lesions in 4 (4.4 %) and non-tumour-related destruction of the femur in 4 patients (4.4%). High-grade tumours were found in the majority of malignant bone tumours (70.7%). Treatment complications, which occurred in 26 patients, were: local recurrence of the tumour, deep infection, acetabular destruction following hemiarthroplasty, recurrent dislocations of endoprosthesis, periprosthetic fracture and hardware problems. In total, 23 patients (25.6%) died due to tumours. Endoprostheses should be considered as a treatment of choice for bone tumours in the hip and knee joint region. Advances in limb salvage surgery are, and will long continue to be, a great challenge for orthopaedic oncologists of the 21st century.

• Ključne riječi (engleski): Artificial Limbs; Bone Nails; Bone Neoplasms - rehabilitation - surgery; Limb Salvage - adverse effects - instrumentation - methods; Adolescent; Adult; Aged; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Bone Cements - therapeutic use; Child; Female; Fractures, Spontaneous - therapy; Humans; Male; Middle Aged; Prosthesis Design; Prosthesis Failure; Retrospective Studies
• Jezik: engleski
• Vrsta publikacije: Znanstveni rad - Izvorni znanstveni rad
• Status objave: Objavljen
• Vrsta recenzije: Recenziran
• Verzija publikacije: Završna verzija rukopisa prihvaćena za objavljivanje (postprint)
• Naslov časopisa: International Orthopaedics
• Brojčani podaci: vol. 30, br. 6, str. 458-464
• p-ISSN: 0341-2695
• DOI: https://doi.org/10.1007/s00264-006-0193-9
• URN:NBN: urn:nbn:hr:105:746059
• Datum objave publikacije: 2006-12
• URL dokumenta: https://doi.org/10.1007/s00264-006-0193-9
• Vrsta resursa: Tekst
• Prava pristupa: Otvoreni pristup
• Datum i vrijeme pohrane: 2024-03-27 19:56:24