prikaz prve stranice dokumenta Leptomeningeal and intramedullary metastases of glioblastoma multiforme in a patient reoperated during adjuvant radiochemotherapy
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Leptomeningeal and intramedullary metastases of glioblastoma multiforme in a patient reoperated during adjuvant radiochemotherapy
World Journal of Surgical Oncology, 11 (2013), 1; 55. https://doi.org/10.1186/1477-7819-11-55
Grah, Josip Joachim; Katalinić, Darko; Štern-Padovan, Ranka; Paladino, Josip; Šantek, Fedor; Juretić, Antonio; Žarković, Kamelija; Pleština, Stjepko; Šupe, Marijana

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Grah, J. J., Katalinić, D., Štern Padovan, R., Paladino, J., Šantek, F., Juretić, A. ... Šupe, M. (2013). Leptomeningeal and intramedullary metastases of glioblastoma multiforme in a patient reoperated during adjuvant radiochemotherapy. World Journal of Surgical Oncology, 11. (1), 55. doi: 10.1186/1477-7819-11-55

Grah, Josip Joachim, et al. "Leptomeningeal and intramedullary metastases of glioblastoma multiforme in a patient reoperated during adjuvant radiochemotherapy." World Journal of Surgical Oncology, vol. 11, br. 1, 2013, str. 55. https://doi.org/10.1186/1477-7819-11-55

Grah, Josip Joachim, Darko Katalinić, Ranka Štern Padovan, Josip Paladino, Fedor Šantek, Antonio Juretić, Kamelija Žarković, Stjepko Pleština i Marijana Šupe. "Leptomeningeal and intramedullary metastases of glioblastoma multiforme in a patient reoperated during adjuvant radiochemotherapy." World Journal of Surgical Oncology 11, br. 1 (2013): 55. https://doi.org/10.1186/1477-7819-11-55

Grah, J. J., et al. (2013) 'Leptomeningeal and intramedullary metastases of glioblastoma multiforme in a patient reoperated during adjuvant radiochemotherapy', World Journal of Surgical Oncology, 11(1), str. 55. doi: 10.1186/1477-7819-11-55

Grah JJ, Katalinić D, Štern Padovan R, Paladino J, Šantek F, Juretić A, i sur.. Leptomeningeal and intramedullary metastases of glioblastoma multiforme in a patient reoperated during adjuvant radiochemotherapy. World Journal of Surgical Oncology [Internet]. 03.2013. [pristupljeno 12.04.2024.];11(1):55. doi: 10.1186/1477-7819-11-55

J. J. Grah, et al., "Leptomeningeal and intramedullary metastases of glioblastoma multiforme in a patient reoperated during adjuvant radiochemotherapy", World Journal of Surgical Oncology, vol. 11, br. 1, str. 55, Ožujak 2013. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:348121. [Citirano: 12.04.2024.]

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Naslov (engleski)Leptomeningeal and intramedullary metastases of glioblastoma multiforme in a patient reoperated during adjuvant radiochemotherapy
AutorJosip Joachim Grah
AutorDarko Katalinić
AutorRanka Štern-Padovan
AutorJosip Paladino
AutorFedor Šantek
AutorAntonio Juretić
AutorKamelija Žarković
AutorStjepko Pleština
AutorMarijana Šupe
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Sažetak (engleski)
Despite huge advances in medicine, glioblastoma multiforme (GBM) remains a highly lethal, fast-growing tumour that cannot be cured by currently available therapies. However, extracranial and extraneural dissemination of GBM is extremely rare, but is being recognised in different imaging studies. To date, the cause of the GBM metastatic spread still remains under discussion. It probably develops at the time of intracranial progression following a surgical procedure. According to other hypothesis, the metastases are a consequence of spontaneous tumour transdural extension or haematogenous dissemination. We present a case of a 59-year-old woman with symptomatic leptomeningeal and intramedullary metastases of GBM who has been previously surgically treated with primary subtotal resection and underwent a repeated surgery during adjuvant radiotherapy and chemotherapy with temozolomide. Today, the main goal of surgery and chemoradiotherapy is to prevent neurologic deterioration and improve health-related quality of life. With this paper, we want to present this rare entity and emphasise the importance of a multidisciplinary approach, a key function in the management of brain tumour patients. The prognosis is still very poor although prolongation of survival can be obtained. Finally, although rare, our case strongly suggests that clinicians should be familiar with the possibility of the extracranial spread of GBM because as treatment improvements provide better control of the primary tumour and improving survival, metastatic disease will be increasingly encountered.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Prikaz slučaja
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaWorld Journal of Surgical Oncology
Brojčani podacivol. 11, br. 1, str. 55
p-ISSN1477-7819
DOIhttps://doi.org/10.1186/1477-7819-11-55
URN:NBNurn:nbn:hr:105:348121
Datum objave publikacije2013-03
URL dokumentahttps://doi.org/10.1186/1477-7819-11-55
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2024-03-27 19:59:16