prikaz prve stranice dokumenta Expression of growth hormone receptor, plakoglobin and NEDD9 protein in association with tumour progression and metastasis in human breast cancer
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Expression of growth hormone receptor, plakoglobin and NEDD9 protein in association with tumour progression and metastasis in human breast cancer
Tumor Biology, 35 (2014), 7; 6425-6434. https://doi.org/10.1007/s13277-014-1827-y
Štajduhar, Emil; Sedić, Mirela; Leniček, Tanja; Radulović, Petra; Kerenji, Aleksandar; Krušlin, Božo; Pavelić, Krešimir; Kraljević Pavelić, Sandra

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Štajduhar, E., Sedić, M., Leniček, T., Radulović, P., Kerenji, A., Krušlin, B. ... Kraljević Pavelić, S. (2014). Expression of growth hormone receptor, plakoglobin and NEDD9 protein in association with tumour progression and metastasis in human breast cancer. Tumor Biology, 35. (7), 6425-6434. doi: 10.1007/s13277-014-1827-y

Štajduhar, Emil, et al. "Expression of growth hormone receptor, plakoglobin and NEDD9 protein in association with tumour progression and metastasis in human breast cancer." Tumor Biology, vol. 35, br. 7, 2014, str. 6425-6434. https://doi.org/10.1007/s13277-014-1827-y

Štajduhar, Emil, Mirela Sedić, Tanja Leniček, Petra Radulović, Aleksandar Kerenji, Božo Krušlin, Krešimir Pavelić i Sandra Kraljević Pavelić. "Expression of growth hormone receptor, plakoglobin and NEDD9 protein in association with tumour progression and metastasis in human breast cancer." Tumor Biology 35, br. 7 (2014): 6425-6434. https://doi.org/10.1007/s13277-014-1827-y

Štajduhar, E., et al. (2014) 'Expression of growth hormone receptor, plakoglobin and NEDD9 protein in association with tumour progression and metastasis in human breast cancer', Tumor Biology, 35(7), str. 6425-6434. doi: 10.1007/s13277-014-1827-y

Štajduhar E, Sedić M, Leniček T, Radulović P, Kerenji A, Krušlin B, i sur.. Expression of growth hormone receptor, plakoglobin and NEDD9 protein in association with tumour progression and metastasis in human breast cancer. Tumor Biology [Internet]. 07.2014. [pristupljeno 10.11.2024.];35(7):6425-6434. doi: 10.1007/s13277-014-1827-y

E. Štajduhar, et al., "Expression of growth hormone receptor, plakoglobin and NEDD9 protein in association with tumour progression and metastasis in human breast cancer", Tumor Biology, vol. 35, br. 7, str. 6425-6434, Srpanj 2014. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:856670. [Citirano: 10.11.2024.]

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Naslov (engleski)Expression of growth hormone receptor, plakoglobin and NEDD9 protein in association with tumour progression and metastasis in human breast cancer
AutorEmil Štajduhar
AutorMirela Sedić
AutorTanja Leniček
AutorPetra Radulović
AutorAleksandar Kerenji
AutorBožo Krušlin
AutorKrešimir Pavelić
AutorSandra Kraljević Pavelić
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Sažetak (engleski)
Breast cancer is the most frequently diagnosed cancer and the leading cause of cancer-related deaths among female population worldwide. Metastases are the common cause of morbidity and mortality in breast cancer and can remain latent for several years after surgical removal of the primary tumour. Thus, the identification and functional characterisation of molecular factors that promote oncogenic signalling in mammary tumour development and progression could provide new entry points for designing targeted therapeutic strategies for metastatic breast cancer. In the present study, we investigated the expression of proteins involved in cell signalling (growth hormone receptor (GHR) and NEDD9) and cell-cell adhesion (plakoglobin) in epithelial and stromal compartments of primary ductal invasive breast carcinomas and their axillary lymph node metastases versus non-metastatic tumours. Obtained data revealed remarkable increase in the expression levels of GHR and NEDD9 proteins in both epithelial and stromal components of axillary lymph node metastases in comparison with those of non-metastatic tumours, suggesting that the expression of these two proteins may provide biomarkers for tumour aggressiveness.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeZavršna verzija rukopisa prihvaćena za objavljivanje (postprint)
Naslov časopisaTumor Biology
Brojčani podacivol. 35, br. 7, str. 6425-6434
p-ISSN1010-4283
DOIhttps://doi.org/10.1007/s13277-014-1827-y
URN:NBNurn:nbn:hr:105:856670
Datum objave publikacije2014-07
URL dokumentahttps://doi.org/10.1007/s13277-014-1827-y
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
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Datum i vrijeme pohrane2024-03-28 08:14:04