prikaz prve stranice dokumenta Autonomic dysfunction in clinically isolated syndrome suggestive of multiple sclerosis
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Autonomic dysfunction in clinically isolated syndrome suggestive of multiple sclerosis
Clinical Neurophysiology, 127 (2016), 1; 864-869. https://doi.org/10.1016/j.clinph.2015.06.010
Crnošija, Luka; Adamec, Ivan; Lovrić, Mila; Junaković, Anamari; Krbot Skorić, Magdalena; Lušić, Ivo; Habek, Mario

Citirajte ovaj rad

Crnošija, L., Adamec, I., Lovrić, M., Junaković, A., Krbot Skorić, M., Lušić, I. i Habek, M. (2016). Autonomic dysfunction in clinically isolated syndrome suggestive of multiple sclerosis. Clinical Neurophysiology, 127. (1), 864-869. doi: 10.1016/j.clinph.2015.06.010

Crnošija, Luka, et al. "Autonomic dysfunction in clinically isolated syndrome suggestive of multiple sclerosis." Clinical Neurophysiology, vol. 127, br. 1, 2016, str. 864-869. https://doi.org/10.1016/j.clinph.2015.06.010

Crnošija, Luka, Ivan Adamec, Mila Lovrić, Anamari Junaković, Magdalena Krbot Skorić, Ivo Lušić i Mario Habek. "Autonomic dysfunction in clinically isolated syndrome suggestive of multiple sclerosis." Clinical Neurophysiology 127, br. 1 (2016): 864-869. https://doi.org/10.1016/j.clinph.2015.06.010

Crnošija, L., et al. (2016) 'Autonomic dysfunction in clinically isolated syndrome suggestive of multiple sclerosis', Clinical Neurophysiology, 127(1), str. 864-869. doi: 10.1016/j.clinph.2015.06.010

Crnošija L, Adamec I, Lovrić M, Junaković A, Krbot Skorić M, Lušić I, i sur.. Autonomic dysfunction in clinically isolated syndrome suggestive of multiple sclerosis. Clinical Neurophysiology [Internet]. 01.2016. [pristupljeno 11.04.2024.];127(1):864-869. doi: 10.1016/j.clinph.2015.06.010

L. Crnošija, et al., "Autonomic dysfunction in clinically isolated syndrome suggestive of multiple sclerosis", Clinical Neurophysiology, vol. 127, br. 1, str. 864-869, Siječanj 2016. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:626285. [Citirano: 11.04.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:105:626285
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Podaci o radu
Naslov (engleski)Autonomic dysfunction in clinically isolated syndrome suggestive of multiple sclerosis
AutorLuka Crnošija
AutorIvan Adamec
AutorMila Lovrić
AutorAnamari Junaković
AutorMagdalena Krbot Skorić
AutorIvo Lušić
AutorMario Habek
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Sažetak (engleski)
OBJECTIVES: The aim of this study was to determine the extent of autonomic dysfunction in patients with clinically isolated syndrome (CIS) by using a standardized battery of autonomic tests in the form of the Composite Autonomic Scoring Scale (CASS). ----- METHODS: This was a prospective, cross sectional study which included 24 consecutive patients who were diagnosed with CIS and 17 healthy controls. In all participants, heart rate and blood pressure responses to the Valsalva maneuver, heart rate response to deep breathing and blood pressure response to passive tilt were performed. In 16 patients, Quantitative Sudomotor Axon Reflex Test (QSART) and catecholamine measurement was performed. ----- RESULTS: The proportion of CIS patients with pathological adrenergic index was statistically significantly higher compared to healthy controls (12 vs 2, p=0.018), while there was no difference in cardiovagal index between groups. Five patients had a sudomotor index of 1 (in 4 there was hypohydrosis <50% and in 1 persistent foot hyperhidrosis). When combining adrenergic, cardiovagal and sudomotor index into CASS, 8 patients (50%) had evidence of autonomic dysfunction, 7 mild and one moderate. ----- CONCLUSION: Sympathetic nervous system is frequently affected in CIS patients. ----- SIGNIFICANCE: CASS is able to detect autonomic nervous system dysfunction in CIS patients.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeZavršna verzija rukopisa prihvaćena za objavljivanje (postprint)
Naslov časopisaClinical Neurophysiology
Brojčani podacivol. 127, br. 1, str. 864-869
p-ISSN1388-2457
DOIhttps://doi.org/10.1016/j.clinph.2015.06.010
URN:NBNurn:nbn:hr:105:626285
Datum objave publikacije2016-01
URL dokumentahttps://doi.org/10.1016/j.clinph.2015.06.010
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2024-03-28 08:54:32