prikaz prve stranice dokumenta Survival prediction of high-risk outborn neonates with congenital diaphragmatic hernia from capillary blood gases
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Survival prediction of high-risk outborn neonates with congenital diaphragmatic hernia from capillary blood gases
BMC Pediatrics, 16 (2016); 114. https://doi.org/10.1186/s12887-016-0658-y
Grizelj, Ruža; Bojanić, Katarina; Pritišanac, Ena; Luetić, Tomislav; Vuković, Jurica; Weingarten, Toby N.; Schroeder, Darrell R.; Sprung, Juraj

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Grizelj, R., Bojanić, K., Pritišanac, E., Luetić, T., Vuković, J., Weingarten, T. N. ... Sprung, J. (2016). Survival prediction of high-risk outborn neonates with congenital diaphragmatic hernia from capillary blood gases. BMC Pediatrics, 16., 114. doi: 10.1186/s12887-016-0658-y

Grizelj, Ruža, et al. "Survival prediction of high-risk outborn neonates with congenital diaphragmatic hernia from capillary blood gases." BMC Pediatrics, vol. 16, 2016, str. 114. https://doi.org/10.1186/s12887-016-0658-y

Grizelj, Ruža, Katarina Bojanić, Ena Pritišanac, Tomislav Luetić, Jurica Vuković, Toby N. Weingarten, Darrell R. Schroeder i Juraj Sprung. "Survival prediction of high-risk outborn neonates with congenital diaphragmatic hernia from capillary blood gases." BMC Pediatrics 16 (2016): 114. https://doi.org/10.1186/s12887-016-0658-y

Grizelj, R., et al. (2016) 'Survival prediction of high-risk outborn neonates with congenital diaphragmatic hernia from capillary blood gases', BMC Pediatrics, 16, str. 114. doi: 10.1186/s12887-016-0658-y

Grizelj R, Bojanić K, Pritišanac E, Luetić T, Vuković J, Weingarten TN, i sur.. Survival prediction of high-risk outborn neonates with congenital diaphragmatic hernia from capillary blood gases. BMC Pediatrics [Internet]. 29.07.2016. [pristupljeno 14.04.2024.];16:114. doi: 10.1186/s12887-016-0658-y

R. Grizelj, et al., "Survival prediction of high-risk outborn neonates with congenital diaphragmatic hernia from capillary blood gases", BMC Pediatrics, vol. 16, str. 114, Srpanj 2016. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:709768. [Citirano: 14.04.2024.]

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Naslov (engleski)Survival prediction of high-risk outborn neonates with congenital diaphragmatic hernia from capillary blood gases
AutorRuža Grizelj
AutorKatarina Bojanić
AutorEna Pritišanac
AutorTomislav Luetić
AutorJurica Vuković
AutorToby N. Weingarten
AutorDarrell R. Schroeder
AutorJuraj Sprung
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Sažetak (engleski)
BACKGROUND: The extent of lung hypoplasia in neonates with congenital diaphragmatic hernia (CDH) can be assessed from gas exchange. We examined the role of preductal capillary blood gases in prognosticating outcome in patients with CDH. ----- METHODS: We retrospectively reviewed demographic data, disease characteristics, and preductal capillary blood gases on admission and within 24 h following admission for 44 high-risk outborn neonates. All neonates were intubated after delivery due to acute respiratory distress, and were emergently transferred via ground ambulance to our unit between 1/2000 and 12/2014. The main outcome measure was survival to hospital discharge and explanatory variables of interest were preductal capillary blood gases obtained on admission and during the first 24 h following admission. ----- RESULTS: Higher ratio of preductal partial pressure of oxygen to fraction of inspired oxygen (PcO2/FIO2) on admission predicted survival (AUC = 0.69, P = 0.04). However, some neonates substantially improve PcO2/FIO2 following initiation of treatment. Among neonates who survived at least 24 h, the highest preductal PcO2/FIO2 achieved in the initial 24 h was the strongest predictor of survival (AUC = 0.87, P = 0.002). Nonsurvivors had a mean admission preductal PcCO2 higher than survivors (91 ± 31 vs. 70 ± 25 mmHg, P = 0.02), and their PcCO2 remained high during the first 24 h of treatment. ----- CONCLUSION: The inability to achieve adequate gas exchange within 24 h of initiation of intensive care treatment is an ominous sign in high-risk outborn neonates with CDH. We suggest that improvement of oxygenation during the first 24 h, along with other relevant clinical signs, should be used when making decisions regarding treatment options in these critically ill neonates.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaBMC Pediatrics
Brojčani podacivol. 16, str. 114
p-ISSN1471-2431
DOIhttps://doi.org/10.1186/s12887-016-0658-y
URN:NBNurn:nbn:hr:105:709768
Datum objave publikacije2016-07-29
URL dokumentahttps://doi.org/10.1186/s12887-016-0658-y
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2024-03-28 08:57:08