prikaz prve stranice dokumenta Diabetic ketosis during hyperglycemic crisis is associated with decreased all-cause mortality in patients with type 2 diabetes mellitus
  Preuzmi
PDF 439.57 KB
Znanstveni rad - Izvorni znanstveni rad
Diabetic ketosis during hyperglycemic crisis is associated with decreased all-cause mortality in patients with type 2 diabetes mellitus
Endocrine, 55 (2017), 1; 139-143. https://doi.org/10.1007/s12020-016-1082-7
Kruljac, Ivan; Ćaćić, Miroslav; Ćaćić, Petra; Ostojić, Vedran; Štefanović, Mario; Šikić, Aljoša; Vrkljan, Milan

Citirajte ovaj rad

Kruljac, I., Ćaćić, M., Ćaćić, P., Ostojić, V., Štefanović, M., Šikić, A. i Vrkljan, M. (2017). Diabetic ketosis during hyperglycemic crisis is associated with decreased all-cause mortality in patients with type 2 diabetes mellitus. Endocrine, 55. (1), 139-143. doi: 10.1007/s12020-016-1082-7

Kruljac, Ivan, et al. "Diabetic ketosis during hyperglycemic crisis is associated with decreased all-cause mortality in patients with type 2 diabetes mellitus." Endocrine, vol. 55, br. 1, 2017, str. 139-143. https://doi.org/10.1007/s12020-016-1082-7

Kruljac, Ivan, Miroslav Ćaćić, Petra Ćaćić, Vedran Ostojić, Mario Štefanović, Aljoša Šikić i Milan Vrkljan. "Diabetic ketosis during hyperglycemic crisis is associated with decreased all-cause mortality in patients with type 2 diabetes mellitus." Endocrine 55, br. 1 (2017): 139-143. https://doi.org/10.1007/s12020-016-1082-7

Kruljac, I., et al. (2017) 'Diabetic ketosis during hyperglycemic crisis is associated with decreased all-cause mortality in patients with type 2 diabetes mellitus', Endocrine, 55(1), str. 139-143. doi: 10.1007/s12020-016-1082-7

Kruljac I, Ćaćić M, Ćaćić P, Ostojić V, Štefanović M, Šikić A, i sur.. Diabetic ketosis during hyperglycemic crisis is associated with decreased all-cause mortality in patients with type 2 diabetes mellitus. Endocrine [Internet]. 01.2017. [pristupljeno 04.05.2024.];55(1):139-143. doi: 10.1007/s12020-016-1082-7

I. Kruljac, et al., "Diabetic ketosis during hyperglycemic crisis is associated with decreased all-cause mortality in patients with type 2 diabetes mellitus", Endocrine, vol. 55, br. 1, str. 139-143, Siječanj 2017. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:743131. [Citirano: 04.05.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:105:743131
Prijavite se u repozitorij kako biste mogli spremiti objekt u svoju listu.
Podaci o radu
Naslov (engleski)Diabetic ketosis during hyperglycemic crisis is associated with decreased all-cause mortality in patients with type 2 diabetes mellitus
AutorIvan Kruljac
AutorMiroslav Ćaćić
AutorPetra Ćaćić
AutorVedran Ostojić
AutorMario Štefanović
AutorAljoša Šikić
AutorMilan Vrkljan
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Sažetak (engleski)
Patients with type 2 diabetes mellitus have impaired ketogenesis due to high serum insulin and low growth hormone levels. Evidence exists that ketone bodies might improve kidney and cardiac function. In theory, improved ketogenesis in diabetics may have positive effects. We aimed to assess the impact of diabetic ketosis on all-cause mortality in patients with type 2 diabetes mellitus presenting with hyperglycemic crisis. We analyzed 486 patients with diabetic ketosis and 486 age and sex-matched patients with non-ketotic hyperglycemia presenting to the emergency department. Cox proportional hazard models were used to analyze the link between patient characteristics and mortality. During an observation time of 33.4 months, death of any cause occurred in 40.9 % of the non-ketotic hyperglycemia group and 30.2 % of the DK group (hazard ratio in the diabetic ketosis group, 0.63; 95 % confidence interval 0.48-0.82; P = 0.0005). Patients with diabetic ketosis had a lower incidence of symptomatic heart failure and had improved renal function. They used less furosemide and antihypertensive drugs, more metformin and lower insulin doses, all of which was independently associated with decreased mortality. Plasma glucose and glycated hemoglobin levels were similar in both groups. Patients with hyperglycemic crisis and diabetic ketosis have decreased all-cause mortality when compared to those with non-ketotic hyperglycemia. diabetic ketosis might be a compensatory mechanism rather than a complication in patients with hyperglycemic crises, but further prospective studies are warranted.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeZavršna verzija rukopisa prihvaćena za objavljivanje (postprint)
Naslov časopisaEndocrine
Brojčani podacivol. 55, br. 1, str. 139-143
p-ISSN1355-008X
DOIhttps://doi.org/10.1007/s12020-016-1082-7
URN:NBNurn:nbn:hr:105:743131
Datum objave publikacije2017-01
URL dokumentahttps://doi.org/10.1007/s12020-016-1082-7
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2024-03-28 08:57:36