prikaz prve stranice dokumenta Botulinum toxin type A in motor nervous system: unexplained observations and new challenges
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Botulinum toxin type A in motor nervous system: unexplained observations and new challenges
Journal of Neural Transmission, 123 (2016), 12; 1415-1421. https://doi.org/10.1007/s00702-016-1611-9
Matak, Ivica; Lacković, Zdravko; Relja, Maja

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Matak, I., Lacković, Z. i Relja, M. (2016). Botulinum toxin type A in motor nervous system: unexplained observations and new challenges. Journal of Neural Transmission, 123. (12), 1415-1421. doi: 10.1007/s00702-016-1611-9

Matak, Ivica, et al. "Botulinum toxin type A in motor nervous system: unexplained observations and new challenges." Journal of Neural Transmission, vol. 123, br. 12, 2016, str. 1415-1421. https://doi.org/10.1007/s00702-016-1611-9

Matak, Ivica, Zdravko Lacković i Maja Relja. "Botulinum toxin type A in motor nervous system: unexplained observations and new challenges." Journal of Neural Transmission 123, br. 12 (2016): 1415-1421. https://doi.org/10.1007/s00702-016-1611-9

Matak, I., Lacković, Z. i Relja, M. (2016) 'Botulinum toxin type A in motor nervous system: unexplained observations and new challenges', Journal of Neural Transmission, 123(12), str. 1415-1421. doi: 10.1007/s00702-016-1611-9

Matak I, Lacković Z, Relja M. Botulinum toxin type A in motor nervous system: unexplained observations and new challenges. Journal of Neural Transmission [Internet]. 12.2016. [pristupljeno 12.04.2024.];123(12):1415-1421. doi: 10.1007/s00702-016-1611-9

I. Matak, Z. Lacković i M. Relja, "Botulinum toxin type A in motor nervous system: unexplained observations and new challenges", Journal of Neural Transmission, vol. 123, br. 12, str. 1415-1421, Prosinac 2016. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:728800. [Citirano: 12.04.2024.]

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Podaci o radu
Naslov (engleski)Botulinum toxin type A in motor nervous system: unexplained observations and new challenges
AutorIvica Matak
AutorZdravko Lacković
AutorMaja Relja
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Temeljne medicinske znanosti
Sažetak (engleski)
In the motor system, botulinum toxin type A (BoNT/A) actions were classically attributed to its well-known peripheral anticholinergic actions in neuromuscular junctions. However, the enzymatic activity of BoNT/A, assessed by the detection of cleaved synaptosomal-associated protein 25 (SNAP-25), was recently detected in motor and sensory regions of the brainstem and spinal cord after toxin peripheral injection in rodents. In sensory regions, the function of BoNT/A activity is associated with its antinociceptive effects, while in motor regions we only know that BoNT/A activity is present. Is it possible that BoNT/A presence in central motor nuclei is without any function? In this brief review, we analyze this question. Limited data available in the literature warrant further investigations of BoNT/A actions in motor nervous system.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Pregledni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeZavršna verzija rukopisa prihvaćena za objavljivanje (postprint)
Naslov časopisaJournal of Neural Transmission
Brojčani podacivol. 123, br. 12, str. 1415-1421
p-ISSN0300-9564
DOIhttps://doi.org/10.1007/s00702-016-1611-9
URN:NBNurn:nbn:hr:105:728800
Datum objave publikacije2016-12
URL dokumentahttp://doi.org/10.1007/s00702-016-1611-9
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2024-03-28 08:58:44