prikaz prve stranice dokumenta Metabolic syndrome modulates association between endothelial lipase and lipid/lipoprotein plasma levels in acute heart failure patients
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Metabolic syndrome modulates association between endothelial lipase and lipid/lipoprotein plasma levels in acute heart failure patients
Scientific Reports, 7 (2017), 1; 1165. https://doi.org/10.1038/s41598-017-01367-2
Potočnjak, Ines; Trbušić, Matias; Dokoza Terešak, Sanda; Radulović, Bojana; Pregartner, Gudrun; Berghold, Andrea; Tiran, Beate; Marsche, Gunther; Degoricija, Vesna; Frank, Saša

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Potočnjak, I., Trbušić, M., Dokoza Terešak, S., Radulović, B., Pregartner, G., Berghold, A. ... Frank, S. (2017). Metabolic syndrome modulates association between endothelial lipase and lipid/lipoprotein plasma levels in acute heart failure patients. Scientific Reports, 7. (1), 1165. doi: 10.1038/s41598-017-01367-2

Potočnjak, Ines, et al. "Metabolic syndrome modulates association between endothelial lipase and lipid/lipoprotein plasma levels in acute heart failure patients." Scientific Reports, vol. 7, br. 1, 2017, str. 1165. https://doi.org/10.1038/s41598-017-01367-2

Potočnjak, Ines, Matias Trbušić, Sanda Dokoza Terešak, Bojana Radulović, Gudrun Pregartner, Andrea Berghold, Beate Tiran, Gunther Marsche, Vesna Degoricija i Saša Frank. "Metabolic syndrome modulates association between endothelial lipase and lipid/lipoprotein plasma levels in acute heart failure patients." Scientific Reports 7, br. 1 (2017): 1165. https://doi.org/10.1038/s41598-017-01367-2

Potočnjak, I., et al. (2017) 'Metabolic syndrome modulates association between endothelial lipase and lipid/lipoprotein plasma levels in acute heart failure patients', Scientific Reports, 7(1), str. 1165. doi: 10.1038/s41598-017-01367-2

Potočnjak I, Trbušić M, Dokoza Terešak S, Radulović B, Pregartner G, Berghold A, i sur.. Metabolic syndrome modulates association between endothelial lipase and lipid/lipoprotein plasma levels in acute heart failure patients. Scientific Reports [Internet]. 26.04.2017. [pristupljeno 01.02.2025.];7(1):1165. doi: 10.1038/s41598-017-01367-2

I. Potočnjak, et al., "Metabolic syndrome modulates association between endothelial lipase and lipid/lipoprotein plasma levels in acute heart failure patients", Scientific Reports, vol. 7, br. 1, str. 1165, Travanj 2017. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:690776. [Citirano: 01.02.2025.]

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Naslov (engleski)Metabolic syndrome modulates association between endothelial lipase and lipid/lipoprotein plasma levels in acute heart failure patients
AutorInes Potočnjak
AutorMatias Trbušić
AutorSanda Dokoza Terešak
AutorBojana Radulović
AutorGudrun Pregartner
AutorAndrea Berghold
AutorBeate Tiran
AutorGunther Marsche
AutorVesna Degoricija
AutorSaša Frank
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Sažetak (engleski)
We hypothesised that the established association of endothelial lipase (EL) plasma levels with atherogenic lipid profile is altered in acute heart failure (AHF) and additionally affected by overlapping metabolic syndrome (MetS). We examined the association of EL plasma levels and lipid/lipoprotein plasma levels in AHF patients without and with overlapping MetS. The study was performed as a single-centre, observational study on 152 AHF patients, out of which 85 had overlapping MetS. In the no-MetS group, EL plasma levels were significantly positively correlated with plasma levels of atherogenic lipids/lipoproteins, including total cholesterol, low-density lipoprotein (LDL)-cholesterol, total LDL particles and triglycerides, but also with plasma levels of antiatherogenic high-density lipoprotein (HDL)-cholesterol, total HDL particles and small HDL particles. In the MetS group, EL plasma levels were positively correlated with triglyceride and small LDL-particle levels, and significantly negatively correlated with plasma levels of large HDL particles as well as with LDL- and HDL-particle size, respectively. EL- and lipid/lipoprotein- plasma levels were different in the no-MetS patients, compared to MetS patients. The association of EL with atherogenic lipid profile is altered in AHF and additionally modified by MetS, which strongly modulates EL- and lipid/lipoprotein-plasma levels in AHF.
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaScientific Reports
Brojčani podacivol. 7, br. 1, str. 1165
p-ISSN2045-2322
DOIhttps://doi.org/10.1038/s41598-017-01367-2
URN:NBNurn:nbn:hr:105:690776
Datum objave publikacije2017-04-26
URL dokumentahttps://doi.org/10.1038/s41598-017-01367-2
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2024-03-28 09:10:36