prikaz prve stranice dokumenta Follicular fluid vascular endothelial growth factor is associated with type of infertility and interferon alpha correlates with endometrial thickness in natural cycle in vitro fertilization
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Follicular fluid vascular endothelial growth factor is associated with type of infertility and interferon alpha correlates with endometrial thickness in natural cycle in vitro fertilization
Reproductive Biology, 18 (2018), 3; 289-294. https://doi.org/10.1016/j.repbio.2018.06.001
Hafner, Daria; Vujišić Živković, Sanja; Bauman, Renato; Kujundžić Tiljak, Mirjana; Papić, Neven; Židovec Lepej, Snježana

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Hafner, D., Vujišić Živković, S., Bauman, R., Kujundžić Tiljak, M., Papić, N. i Židovec Lepej, S. (2018). Follicular fluid vascular endothelial growth factor is associated with type of infertility and interferon alpha correlates with endometrial thickness in natural cycle in vitro fertilization. Reproductive Biology, 18. (3), 289-294. doi: 10.1016/j.repbio.2018.06.001

Hafner, Daria, et al. "Follicular fluid vascular endothelial growth factor is associated with type of infertility and interferon alpha correlates with endometrial thickness in natural cycle in vitro fertilization." Reproductive Biology, vol. 18, br. 3, 2018, str. 289-294. https://doi.org/10.1016/j.repbio.2018.06.001

Hafner, Daria, Sanja Vujišić Živković, Renato Bauman, Mirjana Kujundžić Tiljak, Neven Papić i Snježana Židovec Lepej. "Follicular fluid vascular endothelial growth factor is associated with type of infertility and interferon alpha correlates with endometrial thickness in natural cycle in vitro fertilization." Reproductive Biology 18, br. 3 (2018): 289-294. https://doi.org/10.1016/j.repbio.2018.06.001

Hafner, D., et al. (2018) 'Follicular fluid vascular endothelial growth factor is associated with type of infertility and interferon alpha correlates with endometrial thickness in natural cycle in vitro fertilization', Reproductive Biology, 18(3), str. 289-294. doi: 10.1016/j.repbio.2018.06.001

Hafner D, Vujišić Živković S, Bauman R, Kujundžić Tiljak M, Papić N, Židovec Lepej S. Follicular fluid vascular endothelial growth factor is associated with type of infertility and interferon alpha correlates with endometrial thickness in natural cycle in vitro fertilization. Reproductive Biology [Internet]. 2018. [pristupljeno 11.01.2025.];18(3):289-294. doi: 10.1016/j.repbio.2018.06.001

D. Hafner, S. Vujišić Živković, R. Bauman, M. Kujundžić Tiljak, N. Papić i S. Židovec Lepej, "Follicular fluid vascular endothelial growth factor is associated with type of infertility and interferon alpha correlates with endometrial thickness in natural cycle in vitro fertilization", Reproductive Biology, vol. 18, br. 3, str. 289-294, 2018. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:935747. [Citirano: 11.01.2025.]

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Podaci o radu
Naslov (engleski)Follicular fluid vascular endothelial growth factor is associated with type of infertility and interferon alpha correlates with endometrial thickness in natural cycle in vitro fertilization
AutorDaria Hafner
AutorSanja Vujišić Živković
AutorRenato Bauman
AutorMirjana Kujundžić Tiljak
AutorNeven Papić
AutorSnježana Židovec Lepej
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Sažetak (engleski)
The aim of this study was to analyse the presence of vascular endothelial growth factor (VEGF) and interferon alpha (IFN-α) in the follicular fluid (FF) and their possible influence, as pro-angiogenic or anti-angiogenic factors, on in vitro fertilization outcome. The concentrations of VEGF and IFN-α were correlated with oocyte and embryo quality, concentrations of hormones in the serum, perifollicular blood flow and endometrial thickness. VEGF was detected in all FF samples (median 706.6 pg/ml, range 182.9-6638 pg/ml). IFN-α was detected in 60% of the samples (median 6.5 pg/ml, range 0-79.4 pg/ml), while in 40% of the samples its levels were below the test detection limit. VEGF and IFN-α concentrations did not correlate with the cause of infertility, concentrations of FSH, LH, E2 and prolactin, oocyte or embryo quality. Significantly higher concentrations of VEGF have been found in women with primary compared with secondary infertility (p = 0.011, Mann Whitney test). The concentrations of VEGF and IFN-α did not correlate with the resistance index (RI) on days of hCG administration, follicular aspiration and embryo transfer. However, the concentrations of IFN-α correlated with endometrial thickness on the day of embryo transfer (Spearman correlation coefficient ρ = 0.4107; P < 0.05) but not on days of hCG administration and follicular aspiration. The mechanism of VEGF association with the previous ability of having a child needs to be clarified in future studies. The results of this study indicate a possible role of IFN-α in pathways of endometrial remodelling.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeZavršna verzija rukopisa prihvaćena za objavljivanje (postprint)
Naslov časopisaReproductive Biology
Brojčani podacivol. 18, br. 3, str. 289-294
p-ISSN1642-431X
DOIhttps://doi.org/10.1016/j.repbio.2018.06.001
URN:NBNurn:nbn:hr:105:935747
Datum objave publikacije2018
URL dokumentahttps://doi.org/10.1016/j.repbio.2018.06.001
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
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Datum i vrijeme pohrane2024-03-28 10:20:04