prikaz prve stranice dokumenta Establishing the diagnosis of multiple sclerosis in Croatian patients with clinically isolated syndrome: 2010 versus 2017 McDonald criteria
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Establishing the diagnosis of multiple sclerosis in Croatian patients with clinically isolated syndrome: 2010 versus 2017 McDonald criteria
Multiple Sclerosis and Related Disorders, 25 (2018); 99-103. https://doi.org/10.1016/j.msard.2018.07.035
Habek, Mario; Pavičić, Tin; Ruška, Berislav; Pavlović, Ivan; Gabelić, Tereza; Barun, Barbara; Adamec, Ivan; Crnošija, Luka; Krbot Skorić, Magdalena

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Habek, M., Pavičić, T., Ruška, B., Pavlović, I., Gabelić, T., Barun, B. ... Krbot Skorić, M. (2018). Establishing the diagnosis of multiple sclerosis in Croatian patients with clinically isolated syndrome: 2010 versus 2017 McDonald criteria. Multiple Sclerosis and Related Disorders, 25., 99-103. doi: 10.1016/j.msard.2018.07.035

Habek, Mario, et al. "Establishing the diagnosis of multiple sclerosis in Croatian patients with clinically isolated syndrome: 2010 versus 2017 McDonald criteria." Multiple Sclerosis and Related Disorders, vol. 25, 2018, str. 99-103. https://doi.org/10.1016/j.msard.2018.07.035

Habek, Mario, Tin Pavičić, Berislav Ruška, Ivan Pavlović, Tereza Gabelić, Barbara Barun, Ivan Adamec, Luka Crnošija i Magdalena Krbot Skorić. "Establishing the diagnosis of multiple sclerosis in Croatian patients with clinically isolated syndrome: 2010 versus 2017 McDonald criteria." Multiple Sclerosis and Related Disorders 25 (2018): 99-103. https://doi.org/10.1016/j.msard.2018.07.035

Habek, M., et al. (2018) 'Establishing the diagnosis of multiple sclerosis in Croatian patients with clinically isolated syndrome: 2010 versus 2017 McDonald criteria', Multiple Sclerosis and Related Disorders, 25, str. 99-103. doi: 10.1016/j.msard.2018.07.035

Habek M, Pavičić T, Ruška B, Pavlović I, Gabelić T, Barun B, i sur.. Establishing the diagnosis of multiple sclerosis in Croatian patients with clinically isolated syndrome: 2010 versus 2017 McDonald criteria. Multiple Sclerosis and Related Disorders [Internet]. 10.2018. [pristupljeno 18.10.2024.];25:99-103. doi: 10.1016/j.msard.2018.07.035

M. Habek, et al., "Establishing the diagnosis of multiple sclerosis in Croatian patients with clinically isolated syndrome: 2010 versus 2017 McDonald criteria", Multiple Sclerosis and Related Disorders, vol. 25, str. 99-103, Listopad 2018. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:262218. [Citirano: 18.10.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:105:262218
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Naslov (engleski)Establishing the diagnosis of multiple sclerosis in Croatian patients with clinically isolated syndrome: 2010 versus 2017 McDonald criteria
AutorMario Habek
AutorTin Pavičić
AutorBerislav Ruška
AutorIvan Pavlović
AutorTereza Gabelić
AutorBarbara Barun
AutorIvan Adamec
AutorLuka Crnošija
AutorMagdalena Krbot Skorić
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Sažetak (engleski)
AIM: To compare the sensitivity, specificity and accuracy of the 2010 and 2017 revisions of the McDonald criteria in a Croatian cohort of patients with a clinically isolated syndrome (CIS). ----- METHODS: Prospectively collected data from 113 patients were retrospectively analyzed. Sensitivity, specificity and accuracy for both criteria were calculated regarding conversion to clinically definite multiple sclerosis (Poser CDMS) or multiple sclerosis (MS) (defined as fulfilment of clinical or MRI evidence for dissemination in space and the development of a second relapse and/or ≥1 new T2 lesions on the follow-up MRIs) during a two-year follow-up. Survival analysis was performed to estimate the cumulative risk of patients developing Poser CDMS. Binary logistic regression model was used to determine which variables are statistically significant predictors for the conversion to MS. ----- RESULTS: The 2017 revision had higher sensitivity (85 vs. 30% and 85 vs. 41%) and lower specificity (33 vs. 63% and 63 vs. 85%) compared to the 2010 revisions, for conversion to Poser CDMS and MS, respectively. Patients who did not meet the 2017 McDonald criteria had a higher chance of conversion-free survival for Poser CDMS than those who met the 2017 McDonald criteria (p = 0.037). Results of the multivariate regression analysis revealed that patients who at baseline fulfilled 2017 revisions of the McDonald criteria have the increased likelihood of conversion to MS (Exp(B) 9.68, 95%CI 3.62-25.90, p < 0.00001). ----- CONCLUSION: This study provides new information about the application of the 2017 revisions of the McDonald criteria in a Croatian cohort of patients with typical CIS.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeZavršna verzija rukopisa prihvaćena za objavljivanje (postprint)
Naslov časopisaMultiple Sclerosis and Related Disorders
Brojčani podacivol. 25, str. 99-103
p-ISSN2211-0348
DOIhttps://doi.org/10.1016/j.msard.2018.07.035
URN:NBNurn:nbn:hr:105:262218
Datum objave publikacije2018-10
URL dokumentahttp://doi.org/10.1016/j.msard.2018.07.035
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
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Datum i vrijeme pohrane2024-03-28 10:26:43