prikaz prve stranice dokumenta Serum concentrations of free fatty acids are associated with 3-month mortality in acute heart failure patients
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Serum concentrations of free fatty acids are associated with 3-month mortality in acute heart failure patients
Clinical Chemistry and Laboratory Medicine, 57 (2019), 11; 1799-1804. https://doi.org/10.1515/cclm-2019-0037
Degoricija, Vesna; Trbušić, Matias; Potočnjak, Ines; Radulović, Bojana; Pregartner, Gudrun; Berghold, Andrea; Scharnagl, Hubert; Stojaković, Tatjana; Tiran, Beate; Frank, Saša

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Degoricija, V., Trbušić, M., Potočnjak, I., Radulović, B., Pregartner, G., Berghold, A. ... Frank, S. (2019). Serum concentrations of free fatty acids are associated with 3-month mortality in acute heart failure patients. Clinical Chemistry and Laboratory Medicine, 57. (11), 1799-1804. doi: 10.1515/cclm-2019-0037

Degoricija, Vesna, et al. "Serum concentrations of free fatty acids are associated with 3-month mortality in acute heart failure patients." Clinical Chemistry and Laboratory Medicine, vol. 57, br. 11, 2019, str. 1799-1804. https://doi.org/10.1515/cclm-2019-0037

Degoricija, Vesna, Matias Trbušić, Ines Potočnjak, Bojana Radulović, Gudrun Pregartner, Andrea Berghold, Hubert Scharnagl, Tatjana Stojaković, Beate Tiran i Saša Frank. "Serum concentrations of free fatty acids are associated with 3-month mortality in acute heart failure patients." Clinical Chemistry and Laboratory Medicine 57, br. 11 (2019): 1799-1804. https://doi.org/10.1515/cclm-2019-0037

Degoricija, V., et al. (2019) 'Serum concentrations of free fatty acids are associated with 3-month mortality in acute heart failure patients', Clinical Chemistry and Laboratory Medicine, 57(11), str. 1799-1804. doi: 10.1515/cclm-2019-0037

Degoricija V, Trbušić M, Potočnjak I, Radulović B, Pregartner G, Berghold A, i sur.. Serum concentrations of free fatty acids are associated with 3-month mortality in acute heart failure patients. Clinical Chemistry and Laboratory Medicine [Internet]. 29.10.2019. [pristupljeno 14.04.2024.];57(11):1799-1804. doi: 10.1515/cclm-2019-0037

V. Degoricija, et al., "Serum concentrations of free fatty acids are associated with 3-month mortality in acute heart failure patients", Clinical Chemistry and Laboratory Medicine, vol. 57, br. 11, str. 1799-1804, Listopad 2019. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:046298. [Citirano: 14.04.2024.]

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Naslov (engleski)Serum concentrations of free fatty acids are associated with 3-month mortality in acute heart failure patients
AutorVesna Degoricija
AutorMatias Trbušić
AutorInes Potočnjak
AutorBojana Radulović
AutorGudrun Pregartner
AutorAndrea Berghold
AutorHubert Scharnagl
AutorTatjana Stojaković
AutorBeate Tiran
AutorSaša Frank
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Sažetak (engleski)
Background: Plasma free fatty acids (FFA) are higher in heart failure (HF) patients compared to healthy controls. Considering that the extent of FFA elevation in HF might mirror the severity of HF, we hypothesized that the serum levels of FFA may be a useful prognostic indicator for 3-month mortality in acute heart failure (AHF). ----- Methods: We analyzed the serum samples of AHF patients obtained at admission to the emergency department. Serum levels of FFA were analyzed using an enzymatic reagent on an automatic analyzer. ----- Results: Out of 152 included AHF patients that were originally included, serum samples of 132 patients were available for the quantification of FFA. Of these, 35 (26.5%) died within 3 months of onset of AHF. These patients had significantly higher serum levels of FFA compared to AHF patients who were alive 3 months after onset of AHF. Univariable logistic regression analyses showed a significant positive association of FFA levels with 3-month mortality (odds ratio [OR] 2.76 [95% confidence interval 1.32-6.27], p = 0.010). Importantly, this association remained significant after adjusting for age and sex, as well as for further clinical and laboratory parameters that showed a significant association with 3-month mortality in the univariate analyses. ----- Conclusions: We conclude that the admission serum levels of FFA are associated with 3-month mortality in AHF patients. Therefore, measurements of circulating FFA levels may help identifying high-risk AHF patients.
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaClinical Chemistry and Laboratory Medicine
Brojčani podacivol. 57, br. 11, str. 1799-1804
p-ISSN1434-6621
DOIhttps://doi.org/10.1515/cclm-2019-0037
URN:NBNurn:nbn:hr:105:046298
Datum objave publikacije2019-10-29
URL dokumentahttp://doi.org/10.1515/cclm-2019-0037
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
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Datum i vrijeme pohrane2024-03-28 10:32:07