prikaz prve stranice dokumenta Genomic damage in children accidentally exposed to ionizing radiation: a review of the literature
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Genomic damage in children accidentally exposed to ionizing radiation: a review of the literature
Mutation Research. Reviews in Mutation Research, 658 (2008), 1-2; 111-123. https://doi.org/10.1016/j.mrrev.2007.11.003
Fučić, Aleksandra; Brunborg, Gunnar; Lasan, Ružica; Ježek, Davor; Knudsen, Lisbeth E.; Merlo, Domenico Franco

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Fučić, A., Brunborg, G., Lasan, R., Ježek, D., Knudsen, L. E. i Merlo, D. F. (2008). Genomic damage in children accidentally exposed to ionizing radiation: a review of the literature. Mutation Research. Reviews in Mutation Research, 658. (1-2), 111-123. doi: 10.1016/j.mrrev.2007.11.003

Fučić, Aleksandra, et al. "Genomic damage in children accidentally exposed to ionizing radiation: a review of the literature." Mutation Research. Reviews in Mutation Research, vol. 658, br. 1-2, 2008, str. 111-123. https://doi.org/10.1016/j.mrrev.2007.11.003

Fučić, Aleksandra, Gunnar Brunborg, Ružica Lasan, Davor Ježek, Lisbeth E. Knudsen i Domenico Franco Merlo. "Genomic damage in children accidentally exposed to ionizing radiation: a review of the literature." Mutation Research. Reviews in Mutation Research 658, br. 1-2 (2008): 111-123. https://doi.org/10.1016/j.mrrev.2007.11.003

Fučić, A., et al. (2008) 'Genomic damage in children accidentally exposed to ionizing radiation: a review of the literature', Mutation Research. Reviews in Mutation Research, 658(1-2), str. 111-123. doi: 10.1016/j.mrrev.2007.11.003

Fučić A, Brunborg G, Lasan R, Ježek D, Knudsen LE, Merlo DF. Genomic damage in children accidentally exposed to ionizing radiation: a review of the literature. Mutation Research. Reviews in Mutation Research [Internet]. 2008. [pristupljeno 11.04.2024.];658(1-2):111-123. doi: 10.1016/j.mrrev.2007.11.003

A. Fučić, G. Brunborg, R. Lasan, D. Ježek, L. E. Knudsen i D. F. Merlo, "Genomic damage in children accidentally exposed to ionizing radiation: a review of the literature", Mutation Research. Reviews in Mutation Research, vol. 658, br. 1-2, str. 111-123, 2008. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:341131. [Citirano: 11.04.2024.]

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Naslov (engleski)Genomic damage in children accidentally exposed to ionizing radiation: a review of the literature
AutorAleksandra Fučić
AutorGunnar Brunborg
AutorRužica Lasan
AutorDavor Ježek
AutorLisbeth E. Knudsen
AutorDomenico Franco Merlo
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Temeljne medicinske znanosti
Sažetak (engleski)
During the last decade, our knowledge of the mechanisms by which children respond to exposures to physical and chemical agents present in the environment, has significantly increased. Results of recent projects and programmes focused on children's health underline a specific vulnerability of children to environmental genotoxicants. Environmental research on children predominantly investigates the health effects of air pollution while effects from radiation exposure deserve more attention. The main sources of knowledge on genome damage of children exposed to radiation are studies performed after the Chernobyl nuclear plant accident in 1986. The present review presents and discusses data collected from papers analyzing genome damage in children environmentally exposed to ionizing radiation. Overall, the evidence from the studies conducted following the Chernobyl accident, nuclear tests, environmental radiation pollution and indoor accidental contamination reveals consistently increased chromosome aberration and micronuclei frequency in exposed than in referent children. Future research in this area should be focused on studies providing information on: (a) effects on children caused by low doses of radiation; (b) effects on children from combined exposure to low doses of radiation and chemical agents from food, water and air; and (c) specific effects from exposure during early childhood (radioisotopes from water, radon in homes). Special consideration should also be given to a possible impact of a radiochemical environment to the development of an adaptive response for genomic damage. Interactive databases should be developed to provide integration of cytogenetic data, childhood cancer registry data and information on environmental contamination. The overall aim is to introduce timely and efficient preventive measures, by means of a better knowledge of the early and delayed health effects in children resulting from radiation exposure.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Pregledni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeZavršna verzija rukopisa prihvaćena za objavljivanje (postprint)
Naslov časopisaMutation Research. Reviews in Mutation Research
Brojčani podacivol. 658, br. 1-2, str. 111-123
p-ISSN1383-5742
DOIhttps://doi.org/10.1016/j.mrrev.2007.11.003
URN:NBNurn:nbn:hr:105:341131
Datum objave publikacije2008
URL dokumentahttps://doi.org/10.1016/j.mrrev.2007.11.003
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2024-03-28 10:40:19