prikaz prve stranice dokumenta Development of the fetal neural retina in vitro and in ectopic transplants in vivo
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Development of the fetal neural retina in vitro and in ectopic transplants in vivo
Collegium Antropologicum, 32 (2008), 1; 201-207. urn:nbn:hr:105:145971
Katušić, Ana; Jurić-Lekić, Gordana; Jovanov-Milošević, Nataša; Vlahović, Maja; Ježek, Davor; Šerman, Ljiljana; Sinčić, Nino; Veljanovska, Biljana; Bulić-Jakuš, Floriana

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Katušić, A., Jurić Lekić, G., Jovanov Milošević, N., Vlahović, M., Ježek, D., Šerman, Lj. ... Bulić Jakuš, F. (2008). Development of the fetal neural retina in vitro and in ectopic transplants in vivo. Collegium Antropologicum, 32. (1), 201-207. Preuzeto s https://urn.nsk.hr/urn:nbn:hr:105:145971

Katušić, Ana, et al. "Development of the fetal neural retina in vitro and in ectopic transplants in vivo." Collegium Antropologicum, vol. 32, br. 1, 2008, str. 201-207. https://urn.nsk.hr/urn:nbn:hr:105:145971

Katušić, Ana, Gordana Jurić Lekić, Nataša Jovanov Milošević, Maja Vlahović, Davor Ježek, Ljiljana Šerman, Nino Sinčić, Biljana Veljanovska i Floriana Bulić Jakuš. "Development of the fetal neural retina in vitro and in ectopic transplants in vivo." Collegium Antropologicum 32, br. 1 (2008): 201-207. https://urn.nsk.hr/urn:nbn:hr:105:145971

Katušić, A., et al. (2008) 'Development of the fetal neural retina in vitro and in ectopic transplants in vivo', Collegium Antropologicum, 32(1), str. 201-207. Preuzeto s: https://urn.nsk.hr/urn:nbn:hr:105:145971 (Datum pristupa: 20.04.2024.)

Katušić A, Jurić Lekić G, Jovanov Milošević N, Vlahović M, Ježek D, Šerman Lj, i sur.. Development of the fetal neural retina in vitro and in ectopic transplants in vivo. Collegium Antropologicum [Internet]. 03.2008. [pristupljeno 20.04.2024.];32(1):201-207. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:145971

A. Katušić, et al., "Development of the fetal neural retina in vitro and in ectopic transplants in vivo", Collegium Antropologicum, vol. 32, br. 1, str. 201-207, Ožujak 2008. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:145971. [Citirano: 20.04.2024.]

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Naslov (engleski)Development of the fetal neural retina in vitro and in ectopic transplants in vivo
AutorAna Katušić
AutorGordana Jurić-Lekić
AutorNataša Jovanov-Milošević
AutorMaja Vlahović
AutorDavor Ježek
AutorLjiljana Šerman
AutorNino Sinčić
AutorBiljana Veljanovska
AutorFloriana Bulić-Jakuš
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Temeljne medicinske znanosti
Sažetak (engleski)
Investigation of the developmental potential of immature tissues is important for novel approaches to human regenerative medicine. Development of the fetal neural retina has therefore been investigated in two experimental systems. Retinas were microsurgically isolated from 20-days-old rat fetuses and cultivated in vitro for 12 days or transplanted in vivo under the kidney capsule of adult males for as long as 6 months. Shedding of the photoreceptor outer segment which is a process occurring at the terminal stage of photoreceptor differentiation was observed in culture by transmission electron microscopy (TEM). In transplants, no photoreceptors were found although markers of terminal neural and glial differentiation (e,g. synaptophysin, chromogranin and glial fibrilary acidic protein--GFAP) along with the molecules involved in the process of differentiation (guidance molecule semaphorin IIIA and chondroitin sulfate proteoglycan) were expressed. Semaphorin was differentially expressed being absent from older transplants. Proliferating cell nuclear antigen and nestin (marker of undifferentiated neural cells) were still weakly expressed even in six-months-old transplants. We could conclude that in both our experimental systems fetal neural retina proceeded to differentiate further on. However, even in long-term ectopic transplants a small population of cells still retained the potential for proliferation and has not yet reached the stage of terminal differentiation.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaCollegium Antropologicum
Brojčani podacivol. 32, br. 1, str. 201-207
p-ISSN0350-6134
URN:NBNurn:nbn:hr:105:145971
Datum objave publikacije2008-03
URL dokumentahttps://hrcak.srce.hr/23728
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2024-03-28 10:44:49