prikaz prve stranice dokumenta The role of endothelin-1 and nitric oxide in the pathogenesis of hypertension in diabetic patients
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The role of endothelin-1 and nitric oxide in the pathogenesis of hypertension in diabetic patients
Collegium Antropologicum, 32 (2008), 1; 93-98. urn:nbn:hr:105:678879
Tomić, Monika; Galešić, Krešimir; Morović-Vergles, Jadranka; Romić, Željko; Mikulić, Ivanka

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Tomić, M., Galešić, K., Morović Vergles, J., Romić, Ž. i Mikulić, I. (2008). The role of endothelin-1 and nitric oxide in the pathogenesis of hypertension in diabetic patients. Collegium Antropologicum, 32. (1), 93-98. Preuzeto s https://urn.nsk.hr/urn:nbn:hr:105:678879

Tomić, Monika, et al. "The role of endothelin-1 and nitric oxide in the pathogenesis of hypertension in diabetic patients." Collegium Antropologicum, vol. 32, br. 1, 2008, str. 93-98. https://urn.nsk.hr/urn:nbn:hr:105:678879

Tomić, Monika, Krešimir Galešić, Jadranka Morović Vergles, Željko Romić i Ivanka Mikulić. "The role of endothelin-1 and nitric oxide in the pathogenesis of hypertension in diabetic patients." Collegium Antropologicum 32, br. 1 (2008): 93-98. https://urn.nsk.hr/urn:nbn:hr:105:678879

Tomić, M., et al. (2008) 'The role of endothelin-1 and nitric oxide in the pathogenesis of hypertension in diabetic patients', Collegium Antropologicum, 32(1), str. 93-98. Preuzeto s: https://urn.nsk.hr/urn:nbn:hr:105:678879 (Datum pristupa: 03.05.2024.)

Tomić M, Galešić K, Morović Vergles J, Romić Ž, Mikulić I. The role of endothelin-1 and nitric oxide in the pathogenesis of hypertension in diabetic patients. Collegium Antropologicum [Internet]. 03.2008. [pristupljeno 03.05.2024.];32(1):93-98. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:678879

M. Tomić, K. Galešić, J. Morović Vergles, Ž. Romić i I. Mikulić, "The role of endothelin-1 and nitric oxide in the pathogenesis of hypertension in diabetic patients", Collegium Antropologicum, vol. 32, br. 1, str. 93-98, Ožujak 2008. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:678879. [Citirano: 03.05.2024.]

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Podaci o radu
Naslov (engleski)The role of endothelin-1 and nitric oxide in the pathogenesis of hypertension in diabetic patients
AutorMonika Tomić
AutorKrešimir Galešić
AutorJadranka Morović-Vergles
AutorŽeljko Romić
AutorIvanka Mikulić
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Sažetak (engleski)
The pathogenesis of renal hypertension has not yet been fully clarified. As the potential role of endothelin-1 (ET-1) and nitric oxide (NO) has been postulated, their concentrations were determined in plasma and urine of diabetic patients. The study included 30 diabetic patients (both IDDM and NIDDM) with initial or advanced diabetic nephropathy (decreased endogenous creatinine clearance, proteinuria) and 20 healthy control subjects. The correlation with blood pressure and other renal function parameters was monitored and compared with the control group. Also, the effect of ACE inhibitors (ACEI) on ET-1 and NO patterns was monitored in correlation with arterial hypertension. In diabetic patients that did not receive ACEI therapy, the increase in plasma ET-1 was associated with both systolic and diastolic blood pressure elevation, whereas in those administered ACEI the increase in plasma ET-1 was associated with a systolic blood pressure decline. In addition, the increase in plasma NO was accompanied by a statistically significant decline of both systolic and diastolic blood pressure in diabetic patients receiving ACEI.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaCollegium Antropologicum
Brojčani podacivol. 32, br. 1, str. 93-98
p-ISSN0350-6134
URN:NBNurn:nbn:hr:105:678879
Datum objave publikacije2008-03
URL dokumentahttps://hrcak.srce.hr/22819
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2024-03-28 10:46:35