prikaz prve stranice dokumenta A rapid biochemical and radiological response to the concomitant therapy with temozolomide and radiotherapy in an aggressive ACTH pituitary adenoma
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A rapid biochemical and radiological response to the concomitant therapy with temozolomide and radiotherapy in an aggressive ACTH pituitary adenoma
Case Reports in Endocrinology, 2017 (2017); 2419590. https://doi.org/10.1155/2017/2419590
Mišir Krpan, Ana; Dušek, Tina; Rakušić, Zoran; Solak, Mirsala; Kraljevic, Ivana; Bišof, Vesna; Ozretić, David; Kaštelan, Darko

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Mišir Krpan, A., Dušek, T., Rakušić, Z., Solak, M., Kraljevic, I., Bišof, V. ... Kaštelan, D. (2017). A rapid biochemical and radiological response to the concomitant therapy with temozolomide and radiotherapy in an aggressive ACTH pituitary adenoma. Case Reports in Endocrinology, 2017., 2419590. doi: 10.1155/2017/2419590

Mišir Krpan, Ana, et al. "A rapid biochemical and radiological response to the concomitant therapy with temozolomide and radiotherapy in an aggressive ACTH pituitary adenoma." Case Reports in Endocrinology, vol. 2017, 2017, str. 2419590. https://doi.org/10.1155/2017/2419590

Mišir Krpan, Ana, Tina Dušek, Zoran Rakušić, Mirsala Solak, Ivana Kraljevic, Vesna Bišof, David Ozretić i Darko Kaštelan. "A rapid biochemical and radiological response to the concomitant therapy with temozolomide and radiotherapy in an aggressive ACTH pituitary adenoma." Case Reports in Endocrinology 2017 (2017): 2419590. https://doi.org/10.1155/2017/2419590

Mišir Krpan, A., et al. (2017) 'A rapid biochemical and radiological response to the concomitant therapy with temozolomide and radiotherapy in an aggressive ACTH pituitary adenoma', Case Reports in Endocrinology, 2017, str. 2419590. doi: 10.1155/2017/2419590

Mišir Krpan A, Dušek T, Rakušić Z, Solak M, Kraljevic I, Bišof V, i sur.. A rapid biochemical and radiological response to the concomitant therapy with temozolomide and radiotherapy in an aggressive ACTH pituitary adenoma. Case Reports in Endocrinology [Internet]. 2017. [pristupljeno 10.04.2024.];2017:2419590. doi: 10.1155/2017/2419590

A. Mišir Krpan, et al., "A rapid biochemical and radiological response to the concomitant therapy with temozolomide and radiotherapy in an aggressive ACTH pituitary adenoma", Case Reports in Endocrinology, vol. 2017, str. 2419590, 2017. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:681041. [Citirano: 10.04.2024.]

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Naslov (engleski)A rapid biochemical and radiological response to the concomitant therapy with temozolomide and radiotherapy in an aggressive ACTH pituitary adenoma
AutorAna Mišir Krpan
AutorTina Dušek
AutorZoran Rakušić
AutorMirsala Solak
AutorIvana Kraljevic
AutorVesna Bišof
AutorDavid Ozretić
AutorDarko Kaštelan
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Sažetak (engleski)
Background and Importance: In the last eight years temozolomide (TMZ) has been used as the last-line treatment modality for aggressive pituitary tumors to be applied after the failure of surgery, medical therapy, and radiotherapy. The objective was to achieve a rapid control of tumor growth and hormone normalization with concurrent chemoradiotherapy in a patient with very aggressive ACTH pituitary adenoma. ----- Clinical Presentation: We describe a patient with an aggressive ACTH-producing adenoma treated with concurrent temozolomide and radiotherapy. The patient suffered from an aggressive ACTH adenoma resistant to surgical and medical treatment. After two months of concurrent temozolomide and radiotherapy, cortisol normalization and significant tumor shrinkage were observed. After 22 months of follow-up, there is still no evidence of tumor recurrence. ----- Conclusion: Concurrent treatment with temozolomide and irradiation appears to be highly effective in the achievement of the tumor volume control as well as in the control of ACTH secretion in aggressive ACTH adenoma.
Jezikengleski
Vrsta publikacijeZnanstveni rad - Prikaz slučaja
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaCase Reports in Endocrinology
Brojčani podacivol. 2017, str. 2419590
p-ISSN2090-6501
DOIhttps://doi.org/10.1155/2017/2419590
URN:NBNurn:nbn:hr:105:681041
Datum objave publikacije2017
URL dokumentahttps://doi.org/10.1155/2017/2419590
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
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Datum i vrijeme pohrane2024-04-09 05:47:23