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Is it enough just to demonstrate that the advanced therapy medicinal products do work or we would prefer to keep walking on the Moon?

Regenerative Therapy, 24 (2023); 74-77. https://doi.org/10.1016/j.reth.2023.06.003

Mitrečić, Dinko

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APA 6th Edition

Mitrečić, D. (2023). Is it enough just to demonstrate that the advanced therapy medicinal products do work or we would prefer to keep walking on the Moon?. Regenerative Therapy, 24., 74-77. doi: 10.1016/j.reth.2023.06.003

MLA 8th Edition

Mitrečić, Dinko. "Is it enough just to demonstrate that the advanced therapy medicinal products do work or we would prefer to keep walking on the Moon?." Regenerative Therapy, vol. 24, 2023, str. 74-77. https://doi.org/10.1016/j.reth.2023.06.003

Chicago 17th Edition

Mitrečić, Dinko. "Is it enough just to demonstrate that the advanced therapy medicinal products do work or we would prefer to keep walking on the Moon?." Regenerative Therapy 24 (2023): 74-77. https://doi.org/10.1016/j.reth.2023.06.003

Harvard

Mitrečić, D. (2023) 'Is it enough just to demonstrate that the advanced therapy medicinal products do work or we would prefer to keep walking on the Moon?', Regenerative Therapy, 24, str. 74-77. doi: 10.1016/j.reth.2023.06.003

Vancouver

Mitrečić D. Is it enough just to demonstrate that the advanced therapy medicinal products do work or we would prefer to keep walking on the Moon?. Regenerative Therapy [Internet]. 12.2023. [pristupljeno 16.06.2024.];24:74-77. doi: 10.1016/j.reth.2023.06.003

IEEE

D. Mitrečić, "Is it enough just to demonstrate that the advanced therapy medicinal products do work or we would prefer to keep walking on the Moon?", Regenerative Therapy, vol. 24, str. 74-77, Prosinac 2023. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:025088. [Citirano: 16.06.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:105:025088

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Podaci o radu

Naslov (engleski)	Is it enough just to demonstrate that the advanced therapy medicinal products do work or we would prefer to keep walking on the Moon?
Autor	Dinko Mitrečić
Autorova ustanova	Sveučilište u Zagrebu Medicinski fakultet (HRVATSKI INSTITUT ZA ISTRAŽIVANJE MOZGA)
Autorova ustanova	Sveučilište u Zagrebu Medicinski fakultet (KATEDRA ZA HISTOLOGIJU I EMBRIOLOGIJU)
Znanstveno / umjetničko područje, polje i grana	BIOMEDICINA I ZDRAVSTVO Temeljne medicinske znanosti Citologija, histologija i embriologija
Sažetak (engleski)	After several decades of continuous yet bumpy progress the advanced therapy medicinal products reached the stage when the first drugs with well documented efficacy started to be registered. However, in the disturbing chain of events, many of them were discontinued because of the lack of return on investment. By comparing this phenomenon to the fact that humans did not return to the Moon for already 50 years, primarily because of the lack of dedicated funds, this commentary proposes strategies how to avoid menace of the dead end threating to suffocate progress of the advanced medical therapies. While treatments for rare diseases can be defended by mixture of altruistic, inspiring and rational reasons, mostly covered by the fact that regardless of the price of the newly developed therapy, the total burden remains low, common diseases should be addressed in a different way. This needs to include precise modelling of the benefits which advanced therapy medicinal products bring for every condition, taking in account reduction of the costs of long, often life-long support of patients affected by such diseases. Without intention to steal romantic view on the scientific progress, powerful yet very expensive tools of advanced therapy medicinal products require urgent top-down decisions which include selection of priorities based on the financial modelling. Instead of spontaneous exploration in all directions, this commentary proposes an arranged marriage between scientific community and big investors sustained by combination of governmental requirements in the form of real time data sharing, reimbursement warranties according to demonstrated efficacy and clear recognition of the primary targets with accompanying pre-defined financial frameworks.
Ključne riječi (engleski)
Jezik	engleski
Vrsta publikacije	Stručni rad - Stručni rad
Status objave	Objavljen
Vrsta recenzije	Recenziran
Verzija publikacije	Objavljena verzija rada (izdavačev PDF)
Naslov časopisa	Regenerative Therapy
Brojčani podaci	vol. 24, str. 74-77
p-ISSN	2352-3204
DOI	https://doi.org/10.1016/j.reth.2023.06.003
URN:NBN	urn:nbn:hr:105:025088
Datum objave publikacije	2023-12
URL dokumenta	https://linkinghub.elsevier.com/retrieve/pii/S2352320423000512
Vrsta resursa	Tekst
Prava pristupa	Otvoreni pristup
Uvjeti korištenja
Datum i vrijeme pohrane	2024-05-17 07:50:21