prikaz prve stranice dokumenta Bloodstream Infections by AmpC-Producing Enterobacterales: Risk Factors and Therapeutic Outcome
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Bloodstream Infections by AmpC-Producing Enterobacterales: Risk Factors and Therapeutic Outcome
Pathogens, 12 (2023), 9; 1125. https://doi.org/10.3390/pathogens12091125
Pospišil, Mladen; Car, Haris; Elveđi-Gašparović, Vesna; Beader, Nataša; Herljević, Zoran; Bedenić, Branka

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Pospišil, M., Car, H., Elveđi Gašparović, V., Beader, N., Herljević, Z. i Bedenić, B. (2023). Bloodstream Infections by AmpC-Producing Enterobacterales: Risk Factors and Therapeutic Outcome. Pathogens, 12. (9). doi: 10.3390/pathogens12091125

Pospišil, Mladen, et al. "Bloodstream Infections by AmpC-Producing Enterobacterales: Risk Factors and Therapeutic Outcome." Pathogens, vol. 12, br. 9, 2023. https://doi.org/10.3390/pathogens12091125

Pospišil, Mladen, Haris Car, Vesna Elveđi Gašparović, Nataša Beader, Zoran Herljević i Branka Bedenić. "Bloodstream Infections by AmpC-Producing Enterobacterales: Risk Factors and Therapeutic Outcome." Pathogens 12, br. 9 (2023). https://doi.org/10.3390/pathogens12091125

Pospišil, M., et al. (2023) 'Bloodstream Infections by AmpC-Producing Enterobacterales: Risk Factors and Therapeutic Outcome', Pathogens, 12(9). doi: 10.3390/pathogens12091125

Pospišil M, Car H, Elveđi Gašparović V, Beader N, Herljević Z, Bedenić B. Bloodstream Infections by AmpC-Producing Enterobacterales: Risk Factors and Therapeutic Outcome. Pathogens [Internet]. 03.09.2023. [pristupljeno 16.06.2024.];12(9). doi: 10.3390/pathogens12091125

M. Pospišil, H. Car, V. Elveđi Gašparović, N. Beader, Z. Herljević i B. Bedenić, "Bloodstream Infections by AmpC-Producing Enterobacterales: Risk Factors and Therapeutic Outcome", Pathogens, vol. 12, br. 9, Rujan 2023. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:515558. [Citirano: 16.06.2024.]

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Naslov (engleski)Bloodstream Infections by AmpC-Producing Enterobacterales: Risk Factors and Therapeutic Outcome
AutorMladen Pospišil
AutorHaris Car
AutorVesna Elveđi-Gašparović
AutorNataša Beader
AutorZoran Herljević
AutorBranka Bedenić
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA MEDICINSKU MIKROBIOLOGIJU I PARAZITOLOGIJU)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Ginekologija i opstetricija
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Medicinska mikrobiologija
Sažetak (engleski)
Bloodstream infections associated with AmpC-producing Enterobacterales are severe medical conditions which, without prompt and effective treatment, may have dire ramifications. This study aimed to assess whether certain comorbidities and previous surgical procedures coincide with resistance determinants of AmpC-producing Enterobacterales associated with bloodstream infections. Antibiotic resistance patterns and therapy outcome were also determined. The patients’ data obtained revealed that the prevalence of recent surgical procedures, solid organ tumors, metabolic diseases, kidney and liver failure, and hematological malignancies do not differ between resistant and susceptible isolates of AmpC-producing Enterobacterales. Furthermore, no difference was reported in mortality rates. Regarding antibiotic resistance, 34.52% of isolates were confirmed to be resistant (AmpC hyperproduction, ESBL, or carbapenemase). More than one in five AmpC hyperproducers were reported amid Providencia spp., K. aerogenes, E. cloacae, and C. freundii. strains. Carbapenemases were mostly noted in Providencia spp. followed by M. morganii and K. aerogenes strains. Serratia marcescens had the highest proportion of ESBLsof ESBLs. Resistance to expanded-spectrum cephalosporins of Providencia spp. and K. aerogenes strains exceeded 50%, and resistance to meropenem over 10% was observed only in C. freundii strains. Enterobacterales’ ever-growing resistance to antibiotics is becoming quite a challenge for clinicians and new treatment options are required.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaPathogens
Brojčani podacivol. 12, br. 9, 1125
e-ISSN2076-0817
DOIhttps://doi.org/10.3390/pathogens12091125
URN:NBNurn:nbn:hr:105:515558
Datum objave publikacije2023-09-03
URL dokumentahttps://www.mdpi.com/2076-0817/12/9/1125
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2024-05-20 08:30:17