Radiološka dijagnostika i praćenje terapijskih postupaka kod aneurizme aorte

master's thesis

• Title (english): Radiological diagnosis and monitoring of therapeutic procedures in aortic aneurysms
• Author: Karlo Grulović
• Mentor: Gordana Ivanac (mentor)
• Committee member: Boris Brkljačić (predsjednik povjerenstva)
• Committee member: Milan Radoš (član povjerenstva)
• Committee member: Gordana Ivanac (član povjerenstva)
• Granter: University of Zagreb; School of Medicine; (Department of Radiology); Zagreb
• Defense date and country: 2020-07-17, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences; Radiology

Abstract

Aortalna aneurizma je proširenje lumena aorte. U općoj populaciji najviše zahvaća muškarce starije životne dobi. Godine i genetika pomiješani sa lošim životnim navikama osobe najpouzdaniji su pokazatelj za razvitak ove bolesti. Aneurizma se može nalaziti na uzlaznom dijelu, luku te silaznom dijelu aorte. Od metoda suvremene medicine koje su najkorisnije u otkrivanju, procjeni i praćenju ovog poremećaja koriste se rendgen, metoda koja koristi ionizirajući dio elektromagnetskog spektra kako bi nam dala uvid u stanje unutar organizma koje je golom oku nedostupno. Ultrazvuk koristi vrlo visoke, ljudskom uhu nečujne frekvencije zvučnih valova kako bi na brz i siguran način mogao obaviti pregled aneurizme, dobiti bolji uvid u njezine granice te okolinu. Jedina zamjerka toj metodi je izrazita subjektivnost koja joj u ovom trenutku onemogućava da postane zlatni standard pri analizi pacijenata sa ovim poremećajem. Kompjuterizirana tomografija metoda je koja se bazira na tehnologiji rendgena koju kombinira sa snagom računala da bi proizvela trodimenzionalnu reprezentaciju ljudskog tijela. Magnetska rezonanca je metoda koja ne koristi ionizirajuće zračenje već nam omogućava bolji pregled mekih tkiva jer snima signal vodikovih atoma koji su vezani na vodu ili su dio masnog tkiva. Angiografija je metoda koja se sastoji od unosa radioaktivnih boja u organizam i praćenja istih raznim metodama za snimanje, od rendgena do magneta. Aneurizma se može liječiti lijekovima koji reguliraju krvni tlak i kolesterol. Operativno se liječenju pristupa otvorenom operacijom ili endovaskularno. Nakon operativnog zahvata pacijenti se prate snimanjem kompjuterske tomografije i ultrazvuka.

Abstract (english)

Aortic aneurysm is an enlargement of the aortic lumen. In the general population, it mostly affects older men. The most reliable indicators for the development of this disease are age and genetics mixed together with inadequate life habits. The aneurysm can be located on the ascending part, the arch and the descending part of the aorta. The methods of modern medicine that are most useful in detecting, assessing and monitoring this disorder are X-rays, a method that uses the ionizing portion of the electromagnetic spectrum to give us a window into a condition within the body that the naked eye cannot see. Ultrasound uses very high frequencies of sound waves that are inaudible to the human ear in order to be able to quickly and safely examine the aneurysm, get a better insight into its boundaries and the immediate environment. This method’s problem is the pronounced subjectivity, which at the moment is preventing it from becoming the gold standard in the analysis of patients with this disorder. Computed tomography is a method that relies heavily on X-ray technology, which it combines with the power of a computer processing to produce a three-dimensional representation of the human body. Magnetic resonance imaging is a method that does not use ionizing radiation but allows us a better view of soft tissues because it records the signal of hydrogen atoms that are attached to water or are part of adipose tissue. Angiography is a method that introduces radioactive dyes into the body which can be monitored with various imaging methods, from X-rays to magnets. An aneurysm can be treated with drugs that regulate blood pressure and cholesterol. Surgical treatment is approached by open or endovascular surgery. After the operation, the patients are followed-up by computed tomography and ultrasound.

• Keywords: aneurizma; metode suvremene medicine; liječenje; praćenje
• Keywords (english): aneurysm; methods of modern medicine; treatment; follow up
• Language: croatian
• URN:NBN: urn:nbn:hr:105:063166
• Study programme: Title: Medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2021-04-14 07:57:19