prikaz prve stranice dokumenta Biology of bone morphogenetic protein in bone repair and regeneration: A role for autologous blood coagulum as carrier
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Biology of bone morphogenetic protein in bone repair and regeneration: A role for autologous blood coagulum as carrier
Bone, 141 (2020); 115602. https://doi.org/10.1016/j.bone.2020.115602
Kuber Sampath, T.; Vukičević, Slobodan

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Kuber Sampath, T. i Vukičević, S. (2020). Biology of bone morphogenetic protein in bone repair and regeneration: A role for autologous blood coagulum as carrier. Bone, 141.. doi: 10.1016/j.bone.2020.115602

Kuber Sampath, T. i Slobodan Vukičević. "Biology of bone morphogenetic protein in bone repair and regeneration: A role for autologous blood coagulum as carrier." Bone, vol. 141, 2020. https://doi.org/10.1016/j.bone.2020.115602

Kuber Sampath, T. i Slobodan Vukičević. "Biology of bone morphogenetic protein in bone repair and regeneration: A role for autologous blood coagulum as carrier." Bone 141 (2020). https://doi.org/10.1016/j.bone.2020.115602

Kuber Sampath, T. i Vukičević, S. (2020) 'Biology of bone morphogenetic protein in bone repair and regeneration: A role for autologous blood coagulum as carrier', Bone, 141. doi: 10.1016/j.bone.2020.115602

Kuber Sampath T, Vukičević S. Biology of bone morphogenetic protein in bone repair and regeneration: A role for autologous blood coagulum as carrier. Bone [Internet]. 12.2020. [pristupljeno 19.12.2024.];141. doi: 10.1016/j.bone.2020.115602

T. Kuber Sampath i S. Vukičević, "Biology of bone morphogenetic protein in bone repair and regeneration: A role for autologous blood coagulum as carrier", Bone, vol. 141, Prosinac 2020. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:132506. [Citirano: 19.12.2024.]

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Podaci o radu
Naslov (engleski)Biology of bone morphogenetic protein in bone repair and regeneration: A role for autologous blood coagulum as carrier
AutorT. Kuber Sampath
AutorSlobodan Vukičević
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA ANATOMIJU)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Temeljne medicinske znanosti
Anatomija
Sažetak (engleski)
BMPs were purified from demineralized bone matrix based on their ability to induce new bone in vivo and they represent a large member of the TGF-β superfamily of proteins. BMPs serve as morphogenic signals for mesenchymal stem cell migration, proliferation and subsequently differentiation into cartilage and bone during embryonic development. A BMP when implanted with a collagenous carrier in a rat subcutaneous site is capable of inducing new bone by mimicking the cellular events of embryonic bone formation. Based on this biological principle, BMP2 and BMP7 containing collagenous matrix as carrier have been developed as bone graft substitutes for spine fusion and long bone fractures. Here, we describe a novel autologous bone graft substitute that contains BMP6 delivered within an autologous blood coagulum as carrier and summarize the biology of osteogenic BMPs in the context of bone repair and regeneration specifically the critical role that carrier plays to support osteogenesis.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Pregledni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaBone
Brojčani podacivol. 141, 115602
p-ISSN8756-3282
e-ISSN1873-2763
DOIhttps://doi.org/10.1016/j.bone.2020.115602
URN:NBNurn:nbn:hr:105:132506
Datum objave publikacije2020-12
URL dokumentahttps://linkinghub.elsevier.com/retrieve/pii/S8756328220303823
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2021-05-03 11:31:15