prikaz prve stranice dokumenta Complications of Autologous Stem Cell Transplantation in Multiple Myeloma: Results from the CALM Study
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Complications of Autologous Stem Cell Transplantation in Multiple Myeloma: Results from the CALM Study
Journal of Clinical Medicine, 11 (2022), 12; 3541. https://doi.org/10.3390/jcm11123541
Waszczuk-Gajda, Anna; Penack, Olaf; Sbianchi, Giulia; Koster, Linda; Blaise, Didier; Reményi, Péter; Russell, Nigel; Ljungman, Per; Trneny, Marek; Mayer, Jiri; Iacobelli, Simona; Kobbe, Guido; Scheid, Christof; Apperley, Jane; Touzeau, Cyrille; Lenhoff, Stig; Jantunen, Esa; Anagnostopoulos, Achilles; Paris, Laura; Browne, Paul; Thieblemont, Catherine; Schaap, Nicolaas; Sierra, Jorge; Yakoub-Agha, Ibrahim; Garderet, Laurent; Styczynski, Jan; Schoemans, Helene; Moiseev, Ivan; Duarte, Rafael F.; Perić, Zinaida; Montoto, Silvia; van Biezen, Anja; Mikulska, Malgorzata; Aljurf, Mahmoud; Ruutu, Tapani; Kröger, Nicolaus; Morris, Curly; Koenecke, Christian; Schoenland, Stefan; Basak, Grzegorz W. Više autora...

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Waszczuk Gajda, A., Penack, O., Sbianchi, G., Koster, L., Blaise, D., Reményi, P. ... Basak, G. W. (2022). Complications of Autologous Stem Cell Transplantation in Multiple Myeloma: Results from the CALM Study. Journal of Clinical Medicine, 11. (12). doi: 10.3390/jcm11123541

Waszczuk Gajda, Anna, et al. "Complications of Autologous Stem Cell Transplantation in Multiple Myeloma: Results from the CALM Study." Journal of Clinical Medicine, vol. 11, br. 12, 2022. https://doi.org/10.3390/jcm11123541

Waszczuk Gajda, Anna, Olaf Penack, Giulia Sbianchi, Linda Koster, Didier Blaise, Péter Reményi, Nigel Russell, et al. "Complications of Autologous Stem Cell Transplantation in Multiple Myeloma: Results from the CALM Study." Journal of Clinical Medicine 11, br. 12 (2022). https://doi.org/10.3390/jcm11123541

Waszczuk Gajda, A., et al. (2022) 'Complications of Autologous Stem Cell Transplantation in Multiple Myeloma: Results from the CALM Study', Journal of Clinical Medicine, 11(12). doi: 10.3390/jcm11123541

Waszczuk Gajda A, Penack O, Sbianchi G, Koster L, Blaise D, Reményi P, i sur.. Complications of Autologous Stem Cell Transplantation in Multiple Myeloma: Results from the CALM Study. Journal of Clinical Medicine [Internet]. 20.06.2022. [pristupljeno 05.10.2024.];11(12). doi: 10.3390/jcm11123541

A. Waszczuk Gajda, et al., "Complications of Autologous Stem Cell Transplantation in Multiple Myeloma: Results from the CALM Study", Journal of Clinical Medicine, vol. 11, br. 12, Lipanj 2022. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:473709. [Citirano: 05.10.2024.]

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Naslov (engleski)Complications of Autologous Stem Cell Transplantation in Multiple Myeloma: Results from the CALM Study
AutorAnna Waszczuk-Gajda
AutorOlaf Penack
AutorGiulia Sbianchi
AutorLinda Koster
AutorDidier Blaise
AutorPéter Reményi
AutorNigel Russell
AutorPer Ljungman
AutorMarek Trneny
AutorJiri Mayer
AutorSimona Iacobelli
AutorGuido Kobbe
AutorChristof Scheid
AutorJane Apperley
AutorCyrille Touzeau
AutorStig Lenhoff
AutorEsa Jantunen
AutorAchilles Anagnostopoulos
AutorLaura Paris
AutorPaul Browne
AutorCatherine Thieblemont
AutorNicolaas Schaap
AutorJorge Sierra
AutorIbrahim Yakoub-Agha
AutorLaurent Garderet
AutorJan Styczynski
AutorHelene Schoemans
AutorIvan Moiseev
AutorRafael F. Duarte
AutorZinaida Perić
AutorSilvia Montoto
AutorAnja van Biezen
AutorMalgorzata Mikulska
AutorMahmoud Aljurf
AutorTapani Ruutu
AutorNicolaus Kröger
AutorCurly Morris
AutorChristian Koenecke
AutorStefan Schoenland
AutorGrzegorz W. Basak
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA INTERNU MEDICINU)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Interna medicina
Sažetak (engleski)
Background: The main goal of this post hoc analysis of the Collaboration to Collect Autologous Transplant Outcomes in Lymphoma and Myeloma (CALM) study was to evaluate the rate of short- and long-term infectious and non-infectious complications occurring after ASCT in patients with multiple myeloma (MM). ----- Methods: The analysis included all patients with MM from the CALM study who underwent ≥1 ASCT. The primary endpoint of the analysis was to determine the rate of infectious and non-infectious complications after ASCT and to compare them in three time periods: 0-100 days, 101 days-1 year, and >1 year after the first transplant. ----- Results: The analysis included a total of 3552 patients followed up for a median of 56.7 months (range 0.4-108.1). Complication rates decreased with the time from ASCT with 24.85 cases per 100 patient-years from day 0 to 100 days after the transplant, and <2.31 cases per 100 patient-years from the 101st day. At 100 days after ASC T, 45.7% of patients had complications, with infectious events being twice as frequent as non-infectious complications. Bacterial infections (6.5 cases per 100 patient-years, 95% CI: 6.1-7.0) and gastrointestinal complications (4.7 cases per 100 patient-years, 95% CI: 4.3-5.1) were the most common early events. The pattern of complications changed with time from ASCT. The presence of complications after ASCT was not associated with overall survival. ----- Conclusions: Our data provide a solid basis for comparing ASCT-related complications to those caused by emerging treatments in multiple myeloma, such as CAR T-cell therapy and other immunotherapies.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaJournal of Clinical Medicine
Brojčani podacivol. 11, br. 12, 3541
e-ISSN2077-0383
DOIhttps://doi.org/10.3390/jcm11123541
URN:NBNurn:nbn:hr:105:473709
Datum objave publikacije2022-06-20
URL dokumentahttps://www.mdpi.com/2077-0383/11/12/3541
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2022-12-05 11:48:28