prikaz prve stranice dokumenta Comparison of analgesic effects of single versus repeated injection of botulinum toxin in orofacial formalin test in rats
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Comparison of analgesic effects of single versus repeated injection of botulinum toxin in orofacial formalin test in rats
Journal of Neural Transmission, 120 (2013), 1; 141-144. https://doi.org/10.1007/s00702-012-0846-3
Matak, Ivica; Stracenski, Ivana; Lacković, Zdravko

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Matak, I., Stracenski, I. i Lacković, Z. (2013). Comparison of analgesic effects of single versus repeated injection of botulinum toxin in orofacial formalin test in rats. Journal of Neural Transmission, 120. (1), 141-144. doi: 10.1007/s00702-012-0846-3

Matak, Ivica, et al. "Comparison of analgesic effects of single versus repeated injection of botulinum toxin in orofacial formalin test in rats." Journal of Neural Transmission, vol. 120, br. 1, 2013, str. 141-144. https://doi.org/10.1007/s00702-012-0846-3

Matak, Ivica, Ivana Stracenski i Zdravko Lacković. "Comparison of analgesic effects of single versus repeated injection of botulinum toxin in orofacial formalin test in rats." Journal of Neural Transmission 120, br. 1 (2013): 141-144. https://doi.org/10.1007/s00702-012-0846-3

Matak, I., Stracenski, I. i Lacković, Z. (2013) 'Comparison of analgesic effects of single versus repeated injection of botulinum toxin in orofacial formalin test in rats', Journal of Neural Transmission, 120(1), str. 141-144. doi: 10.1007/s00702-012-0846-3

Matak I, Stracenski I, Lacković Z. Comparison of analgesic effects of single versus repeated injection of botulinum toxin in orofacial formalin test in rats. Journal of Neural Transmission [Internet]. 01.2013. [pristupljeno 19.12.2024.];120(1):141-144. doi: 10.1007/s00702-012-0846-3

I. Matak, I. Stracenski i Z. Lacković, "Comparison of analgesic effects of single versus repeated injection of botulinum toxin in orofacial formalin test in rats", Journal of Neural Transmission, vol. 120, br. 1, str. 141-144, Siječanj 2013. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:186109. [Citirano: 19.12.2024.]

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Podaci o radu
Naslov (engleski)Comparison of analgesic effects of single versus repeated injection of botulinum toxin in orofacial formalin test in rats
AutorIvica Matak
AutorIvana Stracenski
AutorZdravko Lacković
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Temeljne medicinske znanosti
Sažetak (engleski)
Long-term effectiveness and repeated administration of botulinum toxin A are the basis for its use in both neuromuscular disorders and certain painful conditions. Botulinum toxin A has been recently approved for migraine treatment, and its off-label use extends to other craniofacial pain disorders. However, recently it was reported that, after repeated injection, botulinum toxin loses its antinociceptive efficacy in rats. In present study with a similar design, we compared the effects of single and repeated injections of botulinum toxin in formalin-induced orofacial pain. No statistically significant differences were found between single or repeatedly treated animal groups. Our results are in line with the clinical experience and suggest that botulinum toxin can be re-administered in orofacial pain treatment.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Prethodno/kratko priopćenje
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeZavršna verzija rukopisa prihvaćena za objavljivanje (postprint)
Naslov časopisaJournal of Neural Transmission
Brojčani podacivol. 120, br. 1, str. 141-144
p-ISSN0300-9564
DOIhttps://doi.org/10.1007/s00702-012-0846-3
URN:NBNurn:nbn:hr:105:186109
Datum objave publikacije2013-01
URL dokumentahttps://doi.org/10.1007/s00702-012-0846-3
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
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Datum i vrijeme pohrane2024-03-27 19:35:53