prikaz prve stranice dokumenta Krüppel-like transcription factor 8 (Klf8) is expressed and active in the neurons of the mouse brain
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Krüppel-like transcription factor 8 (Klf8) is expressed and active in the neurons of the mouse brain
Gene, 570 (2015), 1; 132-140. https://doi.org/10.1016/j.gene.2015.06.016
Dobrivojević, Marina; Habek, Nikola; Kapuralin, Katarina; Ćurlin, Marija; Gajović, Srećko

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Dobrivojević, M., Habek, N., Kapuralin, K., Ćurlin, M. i Gajović, S. (2015). Krüppel-like transcription factor 8 (Klf8) is expressed and active in the neurons of the mouse brain. Gene, 570. (1), 132-140. doi: 10.1016/j.gene.2015.06.016

Dobrivojević, Marina, et al. "Krüppel-like transcription factor 8 (Klf8) is expressed and active in the neurons of the mouse brain." Gene, vol. 570, br. 1, 2015, str. 132-140. https://doi.org/10.1016/j.gene.2015.06.016

Dobrivojević, Marina, Nikola Habek, Katarina Kapuralin, Marija Ćurlin i Srećko Gajović. "Krüppel-like transcription factor 8 (Klf8) is expressed and active in the neurons of the mouse brain." Gene 570, br. 1 (2015): 132-140. https://doi.org/10.1016/j.gene.2015.06.016

Dobrivojević, M., et al. (2015) 'Krüppel-like transcription factor 8 (Klf8) is expressed and active in the neurons of the mouse brain', Gene, 570(1), str. 132-140. doi: 10.1016/j.gene.2015.06.016

Dobrivojević M, Habek N, Kapuralin K, Ćurlin M, Gajović S. Krüppel-like transcription factor 8 (Klf8) is expressed and active in the neurons of the mouse brain. Gene [Internet]. 01.10.2015. [pristupljeno 27.10.2024.];570(1):132-140. doi: 10.1016/j.gene.2015.06.016

M. Dobrivojević, N. Habek, K. Kapuralin, M. Ćurlin i S. Gajović, "Krüppel-like transcription factor 8 (Klf8) is expressed and active in the neurons of the mouse brain", Gene, vol. 570, br. 1, str. 132-140, Listopad 2015. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:139926. [Citirano: 27.10.2024.]

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Podaci o radu
Naslov (engleski)Krüppel-like transcription factor 8 (Klf8) is expressed and active in the neurons of the mouse brain
AutorMarina Dobrivojević
AutorNikola Habek
AutorKatarina Kapuralin
AutorMarija Ćurlin
AutorSrećko Gajović
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Temeljne medicinske znanosti
Sažetak (engleski)
Krüppel-like transcription factor 8 (KLF8) is a transcription factor suggested to be involved in various cellular events, including malignant cell transformation, still its expression in the adult rodent brain remained unknown. To analyze Klf8 in the mouse brain and to identify cell types expressing it, a specific transgenic Klf8(Gt1Gaj) mouse was used. The resulting Klf8 gene-driven β-galactosidase activity was visualized by X-gal histochemical staining of the brain sections. The obtained results were complemented by in situ RNA hybridization and immunohistochemistry. Klf8 was highly expressed throughout the adult mouse brain gray matter including the cerebral cortex, hippocampus, olfactory bulb, hypothalamus, pallidum, and striatum, but not in the cerebellum. Immunofluorescent double-labeling revealed that KLF8-immunoreactive cells were neurons, and the staining was located in their nucleus. This was the first study showing that Klf8 was highly expressed in various regions of the mouse brain and in particular in the neurons, where it was localized in the cell nuclei.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaGene
Brojčani podacivol. 570, br. 1, str. 132-140
p-ISSN0378-1119
DOIhttps://doi.org/10.1016/j.gene.2015.06.016
URN:NBNurn:nbn:hr:105:139926
Datum objave publikacije2015-10-01
URL dokumentahttps://doi.org/10.1016/j.gene.2015.06.016
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
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Datum i vrijeme pohrane2024-03-28 08:11:11