prikaz prve stranice dokumenta Substituting dietary polyunsaturated fat with monounsaturated fat increases insulin sensitivity in cultured rat hepatocytes
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Substituting dietary polyunsaturated fat with monounsaturated fat increases insulin sensitivity in cultured rat hepatocytes
Collegium Antropologicum, 32 (2008), 1; 119-123. urn:nbn:hr:105:597296
Roša, Jagoda; Baraba, Anja; Bučević, Petra; Đorđijevski, Darija; Antolković, Ivan; Roša, Josip

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Roša, J., Baraba, A., Bučević, P., Đorđijevski, D., Antolković, I. i Roša, J. (2008). Substituting dietary polyunsaturated fat with monounsaturated fat increases insulin sensitivity in cultured rat hepatocytes. Collegium Antropologicum, 32. (1), 119-123. Preuzeto s https://urn.nsk.hr/urn:nbn:hr:105:597296

Roša, Jagoda, et al. "Substituting dietary polyunsaturated fat with monounsaturated fat increases insulin sensitivity in cultured rat hepatocytes." Collegium Antropologicum, vol. 32, br. 1, 2008, str. 119-123. https://urn.nsk.hr/urn:nbn:hr:105:597296

Roša, Jagoda, Anja Baraba, Petra Bučević, Darija Đorđijevski, Ivan Antolković i Josip Roša. "Substituting dietary polyunsaturated fat with monounsaturated fat increases insulin sensitivity in cultured rat hepatocytes." Collegium Antropologicum 32, br. 1 (2008): 119-123. https://urn.nsk.hr/urn:nbn:hr:105:597296

Roša, J., et al. (2008) 'Substituting dietary polyunsaturated fat with monounsaturated fat increases insulin sensitivity in cultured rat hepatocytes', Collegium Antropologicum, 32(1), str. 119-123. Preuzeto s: https://urn.nsk.hr/urn:nbn:hr:105:597296 (Datum pristupa: 18.07.2024.)

Roša J, Baraba A, Bučević P, Đorđijevski D, Antolković I, Roša J. Substituting dietary polyunsaturated fat with monounsaturated fat increases insulin sensitivity in cultured rat hepatocytes. Collegium Antropologicum [Internet]. 03.2008. [pristupljeno 18.07.2024.];32(1):119-123. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:597296

J. Roša, A. Baraba, P. Bučević, D. Đorđijevski, I. Antolković i J. Roša, "Substituting dietary polyunsaturated fat with monounsaturated fat increases insulin sensitivity in cultured rat hepatocytes", Collegium Antropologicum, vol. 32, br. 1, str. 119-123, Ožujak 2008. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:597296. [Citirano: 18.07.2024.]

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Naslov (engleski)Substituting dietary polyunsaturated fat with monounsaturated fat increases insulin sensitivity in cultured rat hepatocytes
AutorJagoda Roša
AutorAnja Baraba
AutorPetra Bučević
AutorDarija Đorđijevski
AutorIvan Antolković
AutorJosip Roša
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Sažetak (engleski)
Increased dietary fat intake generally, and saturated fat specifically, will lead to impairment of insulin action and to development of metabolic syndrome. The aim of this study was to find out changing of hepatic glucose output in dependence of high monounsaturated and high polyunsaturated fat diet and possible direct action of insulin in hepatocytes. Hepatocytes were isolated by a collagenase perfusion technique and cultured for 24 h in M 199 serum-free medium. The glucose production in hepatocytes isolated from rats on high polyunsaturated fat diet, as well as those isolated from rats on high monounsaturated fat diet was significantly higher than in standard controls. Insulin significantly decreased glucose production but only in hepatocytes obtained from rats on high monounsaturated fat diet. On the other side energy expenditure was significantly higher in rats on high monounsaturated fat diet and significantly lower in rats on high polyunsaturated fat diet comparable with animals on standard diet. Monounsaturated fat in Mediterranean diet could have beneficial effect on the development of the metabolic syndrome by increasing insulin sensitivity and energy expenditure.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaCollegium Antropologicum
Brojčani podacivol. 32, br. 1, str. 119-123
p-ISSN0350-6134
URN:NBNurn:nbn:hr:105:597296
Datum objave publikacije2008-03
URL dokumentahttps://hrcak.srce.hr/22824
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2024-03-28 10:45:55