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Near-Infrared Spectroscopy-Guided, Individualized Arterial Blood Pressure Management for Carotid Endarterectomy under General Anesthesia: A Randomized, Controlled Trial
Journal of Clinical Medicine, 12 (2023), 15; 4885. https://doi.org/10.3390/jcm12154885
Tomić Mahečić, Tina; Malojčić, Branko; Tonković, Dinko; Mažar, Mirabel; Baronica, Robert; Juren Meaški, Snježana; Crkvenac Gregorek, Andrea; Meier, Jens; Dünser, Martin W.

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Tomić Mahečić, T., Malojčić, B., Tonković, D., Mažar, M., Baronica, R., Juren Meaški, S. ... Dünser, M. W. (2023). Near-Infrared Spectroscopy-Guided, Individualized Arterial Blood Pressure Management for Carotid Endarterectomy under General Anesthesia: A Randomized, Controlled Trial. Journal of Clinical Medicine, 12. (15). doi: 10.3390/jcm12154885

Tomić Mahečić, Tina, et al. "Near-Infrared Spectroscopy-Guided, Individualized Arterial Blood Pressure Management for Carotid Endarterectomy under General Anesthesia: A Randomized, Controlled Trial." Journal of Clinical Medicine, vol. 12, br. 15, 2023. https://doi.org/10.3390/jcm12154885

Tomić Mahečić, Tina, Branko Malojčić, Dinko Tonković, Mirabel Mažar, Robert Baronica, Snježana Juren Meaški, Andrea Crkvenac Gregorek, Jens Meier i Martin W. Dünser. "Near-Infrared Spectroscopy-Guided, Individualized Arterial Blood Pressure Management for Carotid Endarterectomy under General Anesthesia: A Randomized, Controlled Trial." Journal of Clinical Medicine 12, br. 15 (2023). https://doi.org/10.3390/jcm12154885

Tomić Mahečić, T., et al. (2023) 'Near-Infrared Spectroscopy-Guided, Individualized Arterial Blood Pressure Management for Carotid Endarterectomy under General Anesthesia: A Randomized, Controlled Trial', Journal of Clinical Medicine, 12(15). doi: 10.3390/jcm12154885

Tomić Mahečić T, Malojčić B, Tonković D, Mažar M, Baronica R, Juren Meaški S, i sur.. Near-Infrared Spectroscopy-Guided, Individualized Arterial Blood Pressure Management for Carotid Endarterectomy under General Anesthesia: A Randomized, Controlled Trial. Journal of Clinical Medicine [Internet]. 25.07.2023. [pristupljeno 30.09.2024.];12(15). doi: 10.3390/jcm12154885

T. Tomić Mahečić, et al., "Near-Infrared Spectroscopy-Guided, Individualized Arterial Blood Pressure Management for Carotid Endarterectomy under General Anesthesia: A Randomized, Controlled Trial", Journal of Clinical Medicine, vol. 12, br. 15, Srpanj 2023. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:998267. [Citirano: 30.09.2024.]

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Naslov (engleski)Near-Infrared Spectroscopy-Guided, Individualized Arterial Blood Pressure Management for Carotid Endarterectomy under General Anesthesia: A Randomized, Controlled Trial
AutorTina Tomić Mahečić
AutorBranko Malojčić
AutorDinko Tonković
AutorMirabel Mažar
AutorRobert Baronica
AutorSnježana Juren Meaški
AutorAndrea Crkvenac Gregorek
AutorJens Meier
AutorMartin W. Dünser
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA NEUROLOGIJU)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Neurologija
Sažetak (engleski)
Background: Differences in blood pressure can influence the risk of brain ischemia, perioperative complications, and postoperative neurocognitive function in patients undergoing carotid endarterectomy (CEA). Methods: In this single-center trial, patients scheduled for CEA under general anesthesia were randomized into an intervention group receiving near-infrared spectroscopy (NIRS)-guided blood pressure management during carotid cross-clamping and a control group receiving standard care. The primary endpoint was postoperative neurocognitive function assessed before surgery, on postoperative days 1 and 7, and eight weeks after surgery. Perioperative complications and cerebral autoregulatory capacity were secondary endpoints. Results: Systolic blood pressure (p < 0.001) and norepinephrine doses (89 (54–122) vs. 147 (116–242) µg; p < 0.001) during carotid cross-clamping were lower in the intervention group. No group differences in postoperative neurocognitive function were observed. The rate of perioperative complications was lower in the intervention group than in the control group (3.3 vs. 26.7%, p = 0.03). The breath-holding index did not differ between groups. Conclusions: Postoperative neurocognitive function was comparable between CEA patients undergoing general anesthesia in whom arterial blood pressure during carotid cross-clamping was guided using NIRS and subjects receiving standard care. NIRS-guided, individualized arterial blood pressure management resulted in less vasopressor exposition and a lower rate of perioperative complications.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaJournal of Clinical Medicine
Brojčani podacivol. 12, br. 15, 4885
e-ISSN2077-0383
DOIhttps://doi.org/10.3390/jcm12154885
URN:NBNurn:nbn:hr:105:998267
Datum objave publikacije2023-07-25
URL dokumentahttps://www.mdpi.com/2077-0383/12/15/4885
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2024-09-02 08:29:07