prikaz prve stranice dokumenta Low Level of First Morning Urine Cardiac Troponin I: A Specific Hallmark of Aortic Stenosis Severity
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Low Level of First Morning Urine Cardiac Troponin I: A Specific Hallmark of Aortic Stenosis Severity
Journal of Clinical Medicine, 13 (2024), 9; 2472. https://doi.org/10.3390/jcm13092472
Svaguša, Tomo; Žarak, Marko; Šušnjar, Dubravka; Gjorgjievska, Savica; Varvodić, Josip; Slišković, Nikola; Šestan, Gloria; Kušurin, Marko; Prkačin, Ingrid; Rudež, Igor

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Svaguša, T., Žarak, M., Šušnjar, D., Gjorgjievska, S., Varvodić, J., Slišković, N. ... Rudež, I. (2024). Low Level of First Morning Urine Cardiac Troponin I: A Specific Hallmark of Aortic Stenosis Severity. Journal of Clinical Medicine, 13. (9). doi: 10.3390/jcm13092472

Svaguša, Tomo, et al. "Low Level of First Morning Urine Cardiac Troponin I: A Specific Hallmark of Aortic Stenosis Severity." Journal of Clinical Medicine, vol. 13, br. 9, 2024. https://doi.org/10.3390/jcm13092472

Svaguša, Tomo, Marko Žarak, Dubravka Šušnjar, Savica Gjorgjievska, Josip Varvodić, Nikola Slišković, Gloria Šestan, Marko Kušurin, Ingrid Prkačin i Igor Rudež. "Low Level of First Morning Urine Cardiac Troponin I: A Specific Hallmark of Aortic Stenosis Severity." Journal of Clinical Medicine 13, br. 9 (2024). https://doi.org/10.3390/jcm13092472

Svaguša, T., et al. (2024) 'Low Level of First Morning Urine Cardiac Troponin I: A Specific Hallmark of Aortic Stenosis Severity', Journal of Clinical Medicine, 13(9). doi: 10.3390/jcm13092472

Svaguša T, Žarak M, Šušnjar D, Gjorgjievska S, Varvodić J, Slišković N, i sur.. Low Level of First Morning Urine Cardiac Troponin I: A Specific Hallmark of Aortic Stenosis Severity. Journal of Clinical Medicine [Internet]. 24.04.2024. [pristupljeno 13.03.2025.];13(9). doi: 10.3390/jcm13092472

T. Svaguša, et al., "Low Level of First Morning Urine Cardiac Troponin I: A Specific Hallmark of Aortic Stenosis Severity", Journal of Clinical Medicine, vol. 13, br. 9, Travanj 2024. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:135475. [Citirano: 13.03.2025.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:105:135475
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Naslov (engleski)Low Level of First Morning Urine Cardiac Troponin I: A Specific Hallmark of Aortic Stenosis Severity
AutorTomo Svaguša
AutorMarko Žarak
AutorDubravka Šušnjar
AutorSavica Gjorgjievska
AutorJosip Varvodić
AutorNikola Slišković
AutorGloria Šestan
AutorMarko Kušurin
AutorIngrid Prkačin
AutorIgor Rudež
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA KIRURGIJU)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Kirurgija
Sažetak (engleski)
Background: It has recently been shown that cardiac-specific troponin I concentrations in first morning urine samples can be measured with commercially available tests. Due to their accumulation in the first morning urine, scientific papers indicate a potential predictive value for cardiovascular diseases. Therefore, the aim of this study was to compare the concentration of cardiac troponin I in the first morning urine in patients with severe aortic stenosis and the healthy population. Patients and Methods: Blood and first morning urine samples were collected from 34 healthy individuals (17 female) at University Hospital Merkur and 25 patients with severe aortic stenosis (14 female) before surgical treatment at University Hospital Dubrava. Cardiac troponin I and T values were determined using high-sensitivity assays using commercially available Abbott and Roche tests. Results: Patients with severe aortic stenosis had significantly lower troponin I concentrations in the first morning urine samples (0.3 ng/L (0.1–0.6)) as compared to the healthy population (15.2 ng/L (8.4–19.9)) (p < 0.001). There was no statistically significant difference in troponin T concentrations between healthy individuals and patients with severe aortic stenosis. In parallel, both I and T plasma troponin concentrations were significantly higher in patients with severe aortic stenosis. Conclusions: In patients with severe aortic stenosis, cardiac troponin I values in the first morning urine are significantly lower than in healthy subjects.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaJournal of Clinical Medicine
Brojčani podacivol. 13, br. 9, 2472
e-ISSN2077-0383
DOIhttps://doi.org/10.3390/jcm13092472
URN:NBNurn:nbn:hr:105:135475
Datum objave publikacije2024-04-24
URL dokumentahttps://www.mdpi.com/2077-0383/13/9/2472
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2025-02-20 08:15:40