prikaz prve stranice dokumenta Glioma Stem Cells—Features for New Therapy Design
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Glioma Stem Cells—Features for New Therapy Design
Cancers, 16 (2024), 8; 1557. https://doi.org/10.3390/cancers16081557
Pećina-Šlaus, Nives; Hrašćan, Reno

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Pećina Šlaus, N. i Hrašćan, R. (2024). Glioma Stem Cells—Features for New Therapy Design. Cancers, 16. (8). doi: 10.3390/cancers16081557

Pećina Šlaus, Nives i Reno Hrašćan. "Glioma Stem Cells—Features for New Therapy Design." Cancers, vol. 16, br. 8, 2024. https://doi.org/10.3390/cancers16081557

Pećina Šlaus, Nives i Reno Hrašćan. "Glioma Stem Cells—Features for New Therapy Design." Cancers 16, br. 8 (2024). https://doi.org/10.3390/cancers16081557

Pećina Šlaus, N. i Hrašćan, R. (2024) 'Glioma Stem Cells—Features for New Therapy Design', Cancers, 16(8). doi: 10.3390/cancers16081557

Pećina Šlaus N, Hrašćan R. Glioma Stem Cells—Features for New Therapy Design. Cancers [Internet]. 19.04.2024. [pristupljeno 14.03.2025.];16(8). doi: 10.3390/cancers16081557

N. Pećina Šlaus i R. Hrašćan, "Glioma Stem Cells—Features for New Therapy Design", Cancers, vol. 16, br. 8, Travanj 2024. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:689381. [Citirano: 14.03.2025.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:105:689381
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Podaci o radu
Naslov (engleski)Glioma Stem Cells—Features for New Therapy Design
AutorNives Pećina-Šlaus
AutorReno Hrašćan
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(HRVATSKI INSTITUT ZA ISTRAŽIVANJE MOZGA)
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA MEDICINSKU BIOLOGIJU)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Temeljne medicinske znanosti
Neuroznanost
Sažetak (engleski)
On a molecular level, glioma is very diverse and presents a whole spectrum of specific genetic and epigenetic alterations. The tumors are unfortunately resistant to available therapies and the survival rate is low. The explanation of significant intra- and inter-tumor heterogeneity and the infiltrative capability of gliomas, as well as its resistance to therapy, recurrence and aggressive behavior, lies in a small subset of tumor-initiating cells that behave like stem cells and are known as glioma cancer stem cells (GCSCs). They are responsible for tumor plasticity and are influenced by genetic drivers. Additionally, GCSCs also display greater migratory abilities. A great effort is under way in order to find ways to eliminate or neutralize GCSCs. Many different treatment strategies are currently being explored, including modulation of the tumor microenvironment, posttranscriptional regulation, epigenetic modulation and immunotherapy.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Pregledni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaCancers
Brojčani podacivol. 16, br. 8, 1557
e-ISSN2072-6694
DOIhttps://doi.org/10.3390/cancers16081557
URN:NBNurn:nbn:hr:105:689381
Datum objave publikacije2024-04-19
URL dokumentahttps://www.mdpi.com/2072-6694/16/8/1557
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2025-03-03 10:04:55