prikaz prve stranice dokumenta Current knowledge on the genetic background of developmental dysplasia of the hip and the histomorphological status of the cartilage
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Current knowledge on the genetic background of developmental dysplasia of the hip and the histomorphological status of the cartilage
Croatian Medical Journal, 61 (2020), 3; 260-270. https://doi.org/10.3325/cmj.2020.61.260
Bohaček, Ivan; Plečko, Mihovil; Duvančić, Tea; Smoljanović, Tomislav; Vukasović Barišić, Andreja; Delimar, Domagoj

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Bohaček, I., Plečko, M., Duvančić, T., Smoljanović, T., Vukasović Barišić, A. i Delimar, D. (2020). Current knowledge on the genetic background of developmental dysplasia of the hip and the histomorphological status of the cartilage. Croatian Medical Journal, 61. (3), 260-270. doi: 10.3325/cmj.2020.61.260

Bohaček, Ivan, et al. "Current knowledge on the genetic background of developmental dysplasia of the hip and the histomorphological status of the cartilage." Croatian Medical Journal, vol. 61, br. 3, 2020, str. 260-270. https://doi.org/10.3325/cmj.2020.61.260

Bohaček, Ivan, Mihovil Plečko, Tea Duvančić, Tomislav Smoljanović, Andreja Vukasović Barišić i Domagoj Delimar. "Current knowledge on the genetic background of developmental dysplasia of the hip and the histomorphological status of the cartilage." Croatian Medical Journal 61, br. 3 (2020): 260-270. https://doi.org/10.3325/cmj.2020.61.260

Bohaček, I., et al. (2020) 'Current knowledge on the genetic background of developmental dysplasia of the hip and the histomorphological status of the cartilage', Croatian Medical Journal, 61(3), str. 260-270. doi: 10.3325/cmj.2020.61.260

Bohaček I, Plečko M, Duvančić T, Smoljanović T, Vukasović Barišić A, Delimar D. Current knowledge on the genetic background of developmental dysplasia of the hip and the histomorphological status of the cartilage. Croatian Medical Journal [Internet]. 05.07.2020. [pristupljeno 15.04.2024.];61(3):260-270. doi: 10.3325/cmj.2020.61.260

I. Bohaček, M. Plečko, T. Duvančić, T. Smoljanović, A. Vukasović Barišić i D. Delimar, "Current knowledge on the genetic background of developmental dysplasia of the hip and the histomorphological status of the cartilage", Croatian Medical Journal, vol. 61, br. 3, str. 260-270, Srpanj 2020. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:221472. [Citirano: 15.04.2024.]

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Naslov (engleski)Current knowledge on the genetic background of developmental dysplasia of the hip and the histomorphological status of the cartilage
AutorIvan Bohaček
AutorMihovil Plečko
AutorTea Duvančić
AutorTomislav Smoljanović
AutorAndreja Vukasović Barišić
AutorDomagoj Delimar
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA ORTOPEDIJU)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Ortopedija
Sažetak (engleski)
Developmental dysplasia of the hip (DDH) represents a morphological abnormality characterized by the incongruity of femoral head and acetabulum. It ranges from mild dysplastic changes to complete dislocation. DDH has been associated with several hereditary and environmental risk factors, which could explain the incidence variability among different countries. Numerous genes may be involved in the disease etiology and progression. However, there are controversies in the literature regarding some of these genes. DDH-induced secondary osteoarthritis (OA) is characterized by changes in the macromolecule content of the cartilage and the expression of cartilage degradation markers. In addition, it exhibits a pattern of specific histological changes, with several reported differences between primary and DDH-induced secondary OA. The articular cartilage of patients with DDH shows specific radiological characteristics, including changes visible already in infancy, but also at pre-arthritic stages, early stages of OA, and in fully developed DDH-induced secondary OA. Although DDH has been extensively researched in different disease stages, the etiology of the disorder still remains uncertain. This review focuses on the current knowledge on the histomorphological status of the cartilage and the genetic background of DDH.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Pregledni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaCroatian Medical Journal
Brojčani podacivol. 61, br. 3, str. 260-270
p-ISSN0353-9504
e-ISSN1332-8166
DOIhttps://doi.org/10.3325/cmj.2020.61.260
URN:NBNurn:nbn:hr:105:221472
Datum objave publikacije2020-07-05
URL dokumentahttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7358691/
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje-Nekomercijalno-Bez prerada 4.0 međunarodna (CC BY-NC-ND 4.0)
Datum i vrijeme pohrane2020-10-26 13:14:54