prikaz prve stranice dokumenta Autonomic dysfunction in people with neuromyelitis optica spectrum disorders
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Autonomic dysfunction in people with neuromyelitis optica spectrum disorders
Multiple Sclerosis Journal, 26 (2020), 6; 688-695. https://doi.org/10.1177/1352458519837703
Crnošija, Luka; Krbot Skorić, Magdalena; Andabaka, Marko; Junaković, Anamari; Martinović, Vanja; Ivanović, Jovana; Mesaroš, Šarlota; Pekmezović, Tatjana; Drulović, Jelena; Habek, Mario

Citirajte ovaj rad

Crnošija, L., Krbot Skorić, M., Andabaka, M., Junaković, A., Martinović, V., Ivanović, J. ... Habek, M. (2020). Autonomic dysfunction in people with neuromyelitis optica spectrum disorders. Multiple Sclerosis Journal, 26. (6), 688-695. doi: 10.1177/1352458519837703

Crnošija, Luka, et al. "Autonomic dysfunction in people with neuromyelitis optica spectrum disorders." Multiple Sclerosis Journal, vol. 26, br. 6, 2020, str. 688-695. https://doi.org/10.1177/1352458519837703

Crnošija, Luka, Magdalena Krbot Skorić, Marko Andabaka, Anamari Junaković, Vanja Martinović, Jovana Ivanović, Šarlota Mesaroš, Tatjana Pekmezović, Jelena Drulović i Mario Habek. "Autonomic dysfunction in people with neuromyelitis optica spectrum disorders." Multiple Sclerosis Journal 26, br. 6 (2020): 688-695. https://doi.org/10.1177/1352458519837703

Crnošija, L., et al. (2020) 'Autonomic dysfunction in people with neuromyelitis optica spectrum disorders', Multiple Sclerosis Journal, 26(6), str. 688-695. doi: 10.1177/1352458519837703

Crnošija L, Krbot Skorić M, Andabaka M, Junaković A, Martinović V, Ivanović J, i sur.. Autonomic dysfunction in people with neuromyelitis optica spectrum disorders. Multiple Sclerosis Journal [Internet]. 05.2020. [pristupljeno 13.11.2024.];26(6):688-695. doi: 10.1177/1352458519837703

L. Crnošija, et al., "Autonomic dysfunction in people with neuromyelitis optica spectrum disorders", Multiple Sclerosis Journal, vol. 26, br. 6, str. 688-695, Svibanj 2020. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:997279. [Citirano: 13.11.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:105:997279
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Podaci o radu
Naslov (engleski)Autonomic dysfunction in people with neuromyelitis optica spectrum disorders
AutorLuka Crnošija
AutorMagdalena Krbot Skorić
AutorMarko Andabaka
AutorAnamari Junaković
AutorVanja Martinović
AutorJovana Ivanović
AutorŠarlota Mesaroš
AutorTatjana Pekmezović
AutorJelena Drulović
AutorMario Habek
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA NEUROLOGIJU)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Neurologija
Sažetak (engleski)
Aims: To determine the difference in autonomic symptom burden measured with the Composite Autonomic System Score-31 (COMPASS-31) and presence of objective dysautonomia in people with neuromyelitis optica spectrum disorders (pwNMOSD) compared to people with multiple sclerosis (pwMS). ----- Design/methods: Twenty pwNMOSD and 20 pwMS, matched for age, sex, and disease duration, were enrolled. All patients completed the COMPASS-31. The quantification of cardiovascular autonomic dysfunction (CAD) was made using the two indices of the Composite Autonomic Scoring Scale (CASS): adrenergic index (AI) and cardiovagal index (CI). ----- Results: In all pwNMOSD, COMPASS-31 was >0. Sympathetic dysfunction was present in 8 (40%), parasympathetic dysfunction in 10 (50%), and orthostatic hypotension in 6 (30%) pwNMOSD. This group of patients had higher frequency and level on the pupillomotor domain of the COMPASS-31 compared to pwMS (p = 0.048 and p = 0.006, respectively). A binary logistic regression model showed that drop in diastolic blood pressure (dBP) during tilt-table test and normal function of autonomic nervous system, defined as AI = 0 and CI = 0, were independent predictors of pwNMOSD (p = 0.042 and p = 0.029, respectively). If CAD was present, it was significantly worse in pwNMOSD compared to pwMS (p = 0.003). ----- Conclusion: Significant proportion of pwNMOSD experience dysautonomia, which seems to be different from dysautonomia observed in pwMS.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeZavršna verzija rukopisa prihvaćena za objavljivanje (postprint)
Naslov časopisaMultiple Sclerosis Journal
Brojčani podacivol. 26, br. 6, str. 688-695
p-ISSN1352-4585
e-ISSN1477-0970
DOIhttps://doi.org/10.1177/1352458519837703
URN:NBNurn:nbn:hr:105:997279
Datum objave publikacije2020-05
URL dokumentahttp://journals.sagepub.com/doi/10.1177/1352458519837703
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Datum isteka embarga: 2021-05-31
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2021-01-18 12:29:47