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Clinical practice recommendation on hematopoietic stem cell transplantation for acute myeloid leukemia patients with -internal tandem duplication: a position statement from the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation
Haematologica, 105 (2020), 6; 1507-1516. https://doi.org/10.3324/haematol.2019.243410
Bazarbachi, Ali; Bug, Gesine; Baron, Frederic; Brissot, Eolia; Ciceri, Fabio; Dalle, Iman Abou; Döhner, Hartmut; Esteve, Jordi; Floisand, Yngvar; Giebel, Sebastian; Gilleece, Maria; Gorin, Norbert-Claude; Jabbour, Elias; Aljurf, Mahmoud; Kantarjian, Hagop; Kharfan-Dabaja, Mohamed; Labopin, Myriam; Lanza, Francesco; Malard, Florent; Perić, Zinaida; Prebet, Thomas; Ravandi, Farhad; Ruggeri, Annalisa; Sanz, Jaime; Schmid, Christoph; Shouval, Roni; Spyridonidis, Alexandros; Versluis, Jurjen; Vey, Norbert; Savani, Bipin N; Nagler, Arnon; Mohty, Mohamad Više autora...

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Bazarbachi, A., Bug, G., Baron, F., Brissot, E., Ciceri, F., Dalle, I. A. ... Mohty, M. (2020). Clinical practice recommendation on hematopoietic stem cell transplantation for acute myeloid leukemia patients with -internal tandem duplication: a position statement from the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation. Haematologica, 105. (6), 1507-1516. doi: 10.3324/haematol.2019.243410

Bazarbachi, Ali, et al. "Clinical practice recommendation on hematopoietic stem cell transplantation for acute myeloid leukemia patients with -internal tandem duplication: a position statement from the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation." Haematologica, vol. 105, br. 6, 2020, str. 1507-1516. https://doi.org/10.3324/haematol.2019.243410

Bazarbachi, Ali, Gesine Bug, Frederic Baron, Eolia Brissot, Fabio Ciceri, Iman Abou Dalle, Hartmut Döhner, et al. "Clinical practice recommendation on hematopoietic stem cell transplantation for acute myeloid leukemia patients with -internal tandem duplication: a position statement from the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation." Haematologica 105, br. 6 (2020): 1507-1516. https://doi.org/10.3324/haematol.2019.243410

Bazarbachi, A., et al. (2020) 'Clinical practice recommendation on hematopoietic stem cell transplantation for acute myeloid leukemia patients with -internal tandem duplication: a position statement from the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation', Haematologica, 105(6), str. 1507-1516. doi: 10.3324/haematol.2019.243410

Bazarbachi A, Bug G, Baron F, Brissot E, Ciceri F, Dalle IA, i sur.. Clinical practice recommendation on hematopoietic stem cell transplantation for acute myeloid leukemia patients with -internal tandem duplication: a position statement from the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation. Haematologica [Internet]. 06.2020. [pristupljeno 05.05.2024.];105(6):1507-1516. doi: 10.3324/haematol.2019.243410

A. Bazarbachi, et al., "Clinical practice recommendation on hematopoietic stem cell transplantation for acute myeloid leukemia patients with -internal tandem duplication: a position statement from the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation", Haematologica, vol. 105, br. 6, str. 1507-1516, Lipanj 2020. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:868776. [Citirano: 05.05.2024.]

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Naslov (engleski)Clinical practice recommendation on hematopoietic stem cell transplantation for acute myeloid leukemia patients with -internal tandem duplication: a position statement from the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation
AutorAli Bazarbachi
AutorGesine Bug
AutorFrederic Baron
AutorEolia Brissot
AutorFabio Ciceri
AutorIman Abou Dalle
AutorHartmut Döhner
AutorJordi Esteve
AutorYngvar Floisand
AutorSebastian Giebel
AutorMaria Gilleece
AutorNorbert-Claude Gorin
AutorElias Jabbour
AutorMahmoud Aljurf
AutorHagop Kantarjian
AutorMohamed Kharfan-Dabaja
AutorMyriam Labopin
AutorFrancesco Lanza
AutorFlorent Malard
AutorZinaida Perić
AutorThomas Prebet
AutorFarhad Ravandi
AutorAnnalisa Ruggeri
AutorJaime Sanz
AutorChristoph Schmid
AutorRoni Shouval
AutorAlexandros Spyridonidis
AutorJurjen Versluis
AutorNorbert Vey
AutorBipin N Savani
AutorArnon Nagler
AutorMohamad Mohty
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA INTERNU MEDICINU)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Interna medicina
Sažetak (engleski)
The FMS-like tyrosine kinase 3 (FLT3) gene is mutated in 25-30% of patients with acute myeloid leukemia (AML). Because of the poor prognosis associated with FLT3-internal tandem duplication mutated AML, allogeneic hematopoietic stem-cell transplantation (SCT) was commonly performed in first complete remission. Remarkable progress has been made in frontline treatments with the incorporation of FLT3 inhibitors and the development of highly sensitive minimal/measurable residual disease assays. Similarly, recent progress in allogeneic hematopoietic SCT includes improvement of transplant techniques, the use of haploidentical donors in patients lacking an HLA matched donor, and the introduction of FLT3 inhibitors as post-transplant maintenance therapy. Nevertheless, current transplant strategies vary between centers and differ in terms of transplant indications based on the internal tandem duplication allelic ratio and concomitant nucleophos-min-1 mutation, as well as in terms of post-transplant maintenance/consolidation. This review generated by international leukemia or transplant experts, mostly from the European Society for Blood and Marrow Transplantation, attempts to develop a position statement on best approaches for allogeneic hematopoietic SCT for AML with FLT3-internal tandem duplication including indications for and modalities of such transplants and on the potential optimization of post-transplant maintenance with FLT inhibitors.
Jezikengleski
Vrsta publikacijeStručni rad - Stručni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaHaematologica
Brojčani podacivol. 105, br. 6, str. 1507-1516
p-ISSN0390-6078
e-ISSN1592-8721
DOIhttps://doi.org/10.3324/haematol.2019.243410
URN:NBNurn:nbn:hr:105:868776
Datum objave publikacije2020-06
URL dokumentahttp://www.haematologica.org/lookup/doi/10.3324/haematol.2019.243410
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2021-04-16 11:56:55