prikaz prve stranice dokumenta Conventional disease-modifying agents in rheumatoid arthritis – a review of their current use and role in treatment algorithms
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Conventional disease-modifying agents in rheumatoid arthritis – a review of their current use and role in treatment algorithms
Reumatologia/Rheumatology, 58 (2020), 6; 390-400. https://doi.org/10.5114/reum.2020.101400
Padjen, Ivan; Reihl Crnogaj, Mirna; Anić, Branimir

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Padjen, I., Reihl Crnogaj, M. i Anić, B. (2020). Conventional disease-modifying agents in rheumatoid arthritis – a review of their current use and role in treatment algorithms. Reumatologia/Rheumatology, 58. (6), 390-400. doi: 10.5114/reum.2020.101400

Padjen, Ivan, et al. "Conventional disease-modifying agents in rheumatoid arthritis – a review of their current use and role in treatment algorithms." Reumatologia/Rheumatology, vol. 58, br. 6, 2020, str. 390-400. https://doi.org/10.5114/reum.2020.101400

Padjen, Ivan, Mirna Reihl Crnogaj i Branimir Anić. "Conventional disease-modifying agents in rheumatoid arthritis – a review of their current use and role in treatment algorithms." Reumatologia/Rheumatology 58, br. 6 (2020): 390-400. https://doi.org/10.5114/reum.2020.101400

Padjen, I., Reihl Crnogaj, M. i Anić, B. (2020) 'Conventional disease-modifying agents in rheumatoid arthritis – a review of their current use and role in treatment algorithms', Reumatologia/Rheumatology, 58(6), str. 390-400. doi: 10.5114/reum.2020.101400

Padjen I, Reihl Crnogaj M, Anić B. Conventional disease-modifying agents in rheumatoid arthritis – a review of their current use and role in treatment algorithms. Reumatologia/Rheumatology [Internet]. 2020. [pristupljeno 11.04.2024.];58(6):390-400. doi: 10.5114/reum.2020.101400

I. Padjen, M. Reihl Crnogaj i B. Anić, "Conventional disease-modifying agents in rheumatoid arthritis – a review of their current use and role in treatment algorithms", Reumatologia/Rheumatology, vol. 58, br. 6, str. 390-400, 2020. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:515748. [Citirano: 11.04.2024.]

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Naslov (engleski)Conventional disease-modifying agents in rheumatoid arthritis – a review of their current use and role in treatment algorithms
AutorIvan Padjen
AutorMirna Reihl Crnogaj
AutorBranimir Anić
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA INTERNU MEDICINU)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Interna medicina
Sažetak (engleski)
Despite the development of targeted therapies, conventional synthetic disease-modifying antirheumatic drugs (csDMARDs) remain the cornerstone of treatment of rheumatoid arthritis (RA). A literature search was conducted on treatment recommendations and relevant papers regarding new insights on therapeutics in rheumatoid arthritis. Methotrexate is considered the "anchor drug" due to its high efficacy as monotherapy and in combination with other conventional and targeted agents. Leflunomide and sulfasalazine are sound alternatives, whereas (hydroxy)chloroquine is primarily used in combination with other csDMARDs. Their use is encouraged in all treatment phases - in combination with targeted agents, and with other csDMARDs. Combining different csDMARDs is especially attractive in lower income settings given the evidence proving (almost) equal efficacy and safety of the csDMARD combination approach compared to the combination of targeted agents with a csDMARD. The aim of this review is to provide a clinically oriented insight into the pharmacology of each csDMARD and their place in treatment algorithms.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Pregledni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaReumatologia/Rheumatology
Brojčani podacivol. 58, br. 6, str. 390-400
p-ISSN0034-6233
e-ISSN2084-9834
DOIhttps://doi.org/10.5114/reum.2020.101400
URN:NBNurn:nbn:hr:105:515748
Datum objave publikacije2020
URL dokumentahttps://www.termedia.pl/doi/10.5114/reum.2020.101400
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje-Nekomercijalno-Dijeli pod istim uvjetima 4.0 međunarodna (CC BY-NC-SA 4.0)
Datum i vrijeme pohrane2021-07-06 11:42:46