prikaz prve stranice dokumenta Nonalcoholic Fatty Liver Disease—A Novel Risk Factor for Recurrent Clostridioides difficile Infection
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Nonalcoholic Fatty Liver Disease—A Novel Risk Factor for Recurrent Clostridioides difficile Infection
Antibiotics, 10 (2021), 7; 780. https://doi.org/10.3390/antibiotics10070780
Šamadan, Lara; Jeličić, Mia; Vince, Adriana; Papić, Neven

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Šamadan, L., Jeličić, M., Vince, A. i Papić, N. (2021). Nonalcoholic Fatty Liver Disease—A Novel Risk Factor for Recurrent Clostridioides difficile Infection. Antibiotics, 10. (7). doi: 10.3390/antibiotics10070780

Šamadan, Lara, et al. "Nonalcoholic Fatty Liver Disease—A Novel Risk Factor for Recurrent Clostridioides difficile Infection." Antibiotics, vol. 10, br. 7, 2021. https://doi.org/10.3390/antibiotics10070780

Šamadan, Lara, Mia Jeličić, Adriana Vince i Neven Papić. "Nonalcoholic Fatty Liver Disease—A Novel Risk Factor for Recurrent Clostridioides difficile Infection." Antibiotics 10, br. 7 (2021). https://doi.org/10.3390/antibiotics10070780

Šamadan, L., et al. (2021) 'Nonalcoholic Fatty Liver Disease—A Novel Risk Factor for Recurrent Clostridioides difficile Infection', Antibiotics, 10(7). doi: 10.3390/antibiotics10070780

Šamadan L, Jeličić M, Vince A, Papić N. Nonalcoholic Fatty Liver Disease—A Novel Risk Factor for Recurrent Clostridioides difficile Infection. Antibiotics [Internet]. 27.06.2021. [pristupljeno 05.12.2024.];10(7). doi: 10.3390/antibiotics10070780

L. Šamadan, M. Jeličić, A. Vince i N. Papić, "Nonalcoholic Fatty Liver Disease—A Novel Risk Factor for Recurrent Clostridioides difficile Infection", Antibiotics, vol. 10, br. 7, Lipanj 2021. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:748382. [Citirano: 05.12.2024.]

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Naslov (engleski)Nonalcoholic Fatty Liver Disease—A Novel Risk Factor for Recurrent Clostridioides difficile Infection
AutorLara Šamadan
AutorMia Jeličić
AutorAdriana Vince
AutorNeven Papić
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA INFEKTOLOGIJU)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Infektologija
Sažetak (engleski)
Recurrent Clostridioides difficile infections (rCDI) have a substantial impact on healthcare systems, with limited and often expensive therapeutic options. Nonalcoholic fatty liver disease (NAFLD) affects about 25% of the adult population and is associated with metabolic syndrome, changes in gut microbiome and bile acids biosynthesis, all possibly related with rCDI. The aim of this study was to determine whether NAFLD is a risk factor associated with rCDI. A retrospective cohort study included patients ≥ 60 years hospitalized with CDI. The cohort was divided into two groups: those who were and were not readmitted with CDI within 3 months of discharge. Of the 329 patients included, 107 patients (32.5%) experienced rCDI. Patients with rCDI were older, had higher Charlson Age–Comorbidity Index (CACI) and were more frequently hospitalized within 3 months. Except for chronic kidney disease and NAFLD, which were more frequent in the rCDI group, there were no differences in other comorbidities, antibiotic classes used and duration of antimicrobial therapy. Multivariable Cox regression analysis showed that age >75 years, NAFLD, CACI >6, chronic kidney disease, statins and immobility were associated with rCDI. In conclusion, our study identified NAFLD as a possible new host-related risk factor associated with rCDI.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaAntibiotics
Brojčani podacivol. 10, br. 7, 780
e-ISSN2079-6382
DOIhttps://doi.org/10.3390/antibiotics10070780
URN:NBNurn:nbn:hr:105:748382
Datum objave publikacije2021-06-27
ProjektŠifra: UIP-2019-04-7194
Naziv (hrvatski): Uloga imunih semaforina u nealkoholnoj masnoj bolesti jetre i sepsi
Naziv (engleski): The role of immune semaphorins in NAFLD and sepsis
Kratica: SepsisFAT
Voditelj: Neven Papić
Pravna nadležnost: Hrvatska
Financijer: HRZZ
Linija financiranja: UIP
URL dokumentahttps://www.mdpi.com/2079-6382/10/7/780
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2022-06-15 12:11:46