Impact of preoperative antibiotic use in preventing complications of cochlear implantation surgery

Znanstveni rad - Izvorni znanstveni rad

• Autor: Andro Košec
• Autor: Josipa Živko
• Autor: Stela Marković
• Autor: Vladimir Bedeković
• Autor: Mihael Ries
• Autor: Jakov Ajduk
• Autorova ustanova: Sveučilište u Zagrebu; Medicinski fakultet; (KATEDRA ZA OTORINOLARINGOLOGIJU I KIRURGIJU GLAVE I VRATA)
• Znanstveno / umjetničko područje, polje i grana: BIOMEDICINA I ZDRAVSTVO; Kliničke medicinske znanosti; Otorinolaringologija

Sažetak (engleski)

Objective: To examine the impact of preoperative antibiotic prophylaxis on the occurrence of postoperative complications.
-----
Materials and methods: Data of 491 patients undergoing cochlear implantation were included in a non-randomized retrospective comparative cohort study. Demographic data, cochlear implant and surgical details, use of preoperative antibiotics and occurrence of postoperative complications were analyzed using a binary logistic regression model.
-----
Results: There were 317 patients (64.56%) who did not receive preoperative antibiotic prophylaxis and 174 (35.44%) patients who received preoperative antibiotic prophylaxis with ceftriaxone. The overall rate of complications requiring surgical treatment was 2.85%. Younger patient age was identified as a positive predictive factor for administering preoperative antibiotic prophylaxis (p<0.001, OR 1.05 CI 95% 1.0124-1.0826). No difference in complication rate was observed between the two groups. No correlation between sex, age, manufacturer, surgeon and postoperative complications were noted (p=0.45).
-----
Conclusion: There is insufficient evidence to inform decision making regarding preoperative intravenous ceftriaxone use for prevention of infection after cochlear implantation surgery, with data failing to show that administration of preoperative antibiotics leads to a decrease in complication rate. Considering a very low overall complication rate, with few complications related to infection, routine use of preoperative antibiotic prophylaxis should be analyzed further.

• Ključne riječi (engleski): Anti-Bacterial Agents / therapeutic use; Ceftriaxone / therapeutic use; Cochlear Implantation / adverse effects; Cohort Studies; Humans; Postoperative Complications / etiology; Postoperative Complications / prevention & control; Retrospective Studies; Surgical Wound Infection / prevention & control
• Jezik: engleski
• Vrsta publikacije: Znanstveni rad - Izvorni znanstveni rad
• Status objave: Objavljen
• Vrsta recenzije: Recenziran
• Verzija publikacije: Završna verzija rukopisa prihvaćena za objavljivanje (postprint)
• Naslov časopisa: Cochlear Implants International
• Brojčani podaci: vol. 23, br. 3, str. 134-138
• p-ISSN: 1467-0100
• e-ISSN: 1754-7628
• DOI: https://doi.org/10.1080/14670100.2021.2013586
• URN:NBN: urn:nbn:hr:105:375063
• Datum objave publikacije: 2022-05
• URL dokumenta: https://www.tandfonline.com/doi/full/10.1080/14670100.2021.2013586
• Vrsta resursa: Tekst
• Prava pristupa: Otvoreni pristup; Datum isteka embarga: 2023-06-01
• Datum i vrijeme pohrane: 2022-06-27 09:10:52