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Early Assessment of Neoadjuvant Chemotherapy Response Using Multiparametric Magnetic Resonance Imaging in Luminal B-like Subtype of Breast Cancer Patients: A Single-Center Prospective Study
Diagnostics, 13 (2023), 4; 694. https://doi.org/10.3390/diagnostics13040694
Kovačević, Lucija; Petrovečki, Marko; Korša, Lea; Marušić, Zlatko; Dumić-Čule, Ivo; Prutki, Maja

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Kovačević, L., Petrovečki, M., Korša, L., Marušić, Z., Dumić Čule, I. i Prutki, M. (2023). Early Assessment of Neoadjuvant Chemotherapy Response Using Multiparametric Magnetic Resonance Imaging in Luminal B-like Subtype of Breast Cancer Patients: A Single-Center Prospective Study. Diagnostics, 13. (4). doi: 10.3390/diagnostics13040694

Kovačević, Lucija, et al. "Early Assessment of Neoadjuvant Chemotherapy Response Using Multiparametric Magnetic Resonance Imaging in Luminal B-like Subtype of Breast Cancer Patients: A Single-Center Prospective Study." Diagnostics, vol. 13, br. 4, 2023. https://doi.org/10.3390/diagnostics13040694

Kovačević, Lucija, Marko Petrovečki, Lea Korša, Zlatko Marušić, Ivo Dumić Čule i Maja Prutki. "Early Assessment of Neoadjuvant Chemotherapy Response Using Multiparametric Magnetic Resonance Imaging in Luminal B-like Subtype of Breast Cancer Patients: A Single-Center Prospective Study." Diagnostics 13, br. 4 (2023). https://doi.org/10.3390/diagnostics13040694

Kovačević, L., et al. (2023) 'Early Assessment of Neoadjuvant Chemotherapy Response Using Multiparametric Magnetic Resonance Imaging in Luminal B-like Subtype of Breast Cancer Patients: A Single-Center Prospective Study', Diagnostics, 13(4). doi: 10.3390/diagnostics13040694

Kovačević L, Petrovečki M, Korša L, Marušić Z, Dumić Čule I, Prutki M. Early Assessment of Neoadjuvant Chemotherapy Response Using Multiparametric Magnetic Resonance Imaging in Luminal B-like Subtype of Breast Cancer Patients: A Single-Center Prospective Study. Diagnostics [Internet]. 12.02.2023. [pristupljeno 01.12.2024.];13(4). doi: 10.3390/diagnostics13040694

L. Kovačević, M. Petrovečki, L. Korša, Z. Marušić, I. Dumić Čule i M. Prutki, "Early Assessment of Neoadjuvant Chemotherapy Response Using Multiparametric Magnetic Resonance Imaging in Luminal B-like Subtype of Breast Cancer Patients: A Single-Center Prospective Study", Diagnostics, vol. 13, br. 4, Veljača 2023. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:816422. [Citirano: 01.12.2024.]

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Naslov (engleski)Early Assessment of Neoadjuvant Chemotherapy Response Using Multiparametric Magnetic Resonance Imaging in Luminal B-like Subtype of Breast Cancer Patients: A Single-Center Prospective Study
AutorLucija Kovačević
AutorMarko Petrovečki
AutorLea Korša
AutorZlatko Marušić
AutorIvo Dumić-Čule
AutorMaja Prutki
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA RADIOLOGIJU)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Radiologija
Sažetak (engleski)
This study aimed to evaluate the performance of multiparametric breast magnetic resonance imaging (mpMRI) for predicting response to neoadjuvant chemotherapy (NAC) in patients with luminal B subtype breast cancer. The prospective study included thirty-five patients treated with NAC for both early and locally advanced breast cancer of the luminal B subtype at the University Hospital Centre Zagreb between January 2015 and December 2018. All patients underwent breast mpMRI before and after two cycles of NAC. Evaluation of mpMRI examinations included analysis of both morphological (shape, margins, and pattern of enhancement) and kinetic characteristics (initial signal increase and post-initial behavior of the time-signal intensity curve), which were additionally interpreted with a Göttingen score (GS). Histopathological analysis of surgical specimens included grading the tumor response based on the residual cancer burden (RCB) grading system and revealed 29 NAC responders (RCB-0 (pCR), I, II) and 6 NAC non-responders (RCB-III). Changes in GS were compared with RCB classes. A lack of GS decrease after the second cycle of NAC is associated with RCB class and non-responders to NAC.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaDiagnostics
Brojčani podacivol. 13, br. 4, 694
e-ISSN2075-4418
DOIhttps://doi.org/10.3390/diagnostics13040694
URN:NBNurn:nbn:hr:105:816422
Datum objave publikacije2023-02-12
URL dokumentahttps://www.mdpi.com/2075-4418/13/4/694
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2024-01-15 08:27:45